Season 2 Episode 8 | The Science Of Neurodegeneration and the Aging Brain| Dr. Silvia Vicenzi, Postdoctoral Researcher at UCSD
Dr. Silvia Vicenzi, a postdoctoral fellow at UC San Diego, discussed her journey from Italy to the U.S., highlighting her diverse educational background in biotechnology, molecular medicine, and neuroscience. She shared her research on bone marrow aging and its implications for cancer, using unique mouse models. Dr. Vicenzi emphasized the importance of biomarkers in early disease detection and personalized treatment. She also discussed her passion for mentoring students and her efforts to create a supportive community for postdoctoral researchers. Dr. Vicenzi's work aims to bridge basic biology with clinical applications, focusing on healthy aging and disease prevention.
Introduction to the Science Of Podcast Series
* Introduction to the podcast, emphasizing curiosity and the exploration of various scientific topics.
* The podcast is hosted by students from the Jackie Robinson Family YMCA and the Elementary Institute of Science in partnership with UCSD Moores Cancer Center and UCSD campus.
* Funding for the program is provided by Cloudcast Media.
* Insight to the episode's focus on molecular mechanisms related to brain, cancer, and aging.
Meet the Co-Hosts and Guest
* Danielle-Elizabeth Mensah-Baah and her co-host, Dalia, a community health liaison at UCSD Moores Cancer Center.
* Michaela, a senior at Lincoln High School, introduces herself.
* The co-hosts express excitement about the episode and the guest, Dr. Silvia Vicenzi.
Dr. Silvia Vicenzi's Background
* Dr. Vicenzi shares her background, starting from her childhood in Italy, her curiosity, and her early interest in math, biology, and physics.
* She describes her educational journey, including her undergraduate degree in biotechnology, her internship in the UK, and her master's degree in Sweden.
* Dr. Vicenzi discusses her PhD in Australia, focusing on brain wiring and axon guidance, and her postdoctoral training at UC San Diego.
Impact of Studying in Different Countries
* Dr. Vicenzi explains that her global perspective and ability to adapt to different methods have enriched her approach to science.
* She emphasizes the importance of traveling and gaining diverse experiences to broaden one's knowledge and skills.
* Dr. Vicenzi shares how her experiences have helped her develop a unique approach to solving scientific challenges.
Fun Questions and Personal Insights
* Dr. Vicenzi shares that she would have coffee with Rita Levi Montalcini, a Nobel Prize winner from Italy, and discusses her admiration for Montalcini's resilience and contributions to science.
* She reveals her favorite midnight snack is pizza and her dream destination is the Galapagos Islands.
* Dr. Vicenzi shares that her biggest inspiration is her grandfather, who was a strong advocate for justice and values.
Dr. Vicenzi's Current Research and Mentoring Role
* Dr. Vicenzi describes her role as a postdoctoral fellow, leading projects on blood cancers and hematologic malignancies.
* She emphasizes her passion for mentoring students, helping them achieve their goals, and providing support through challenges.
* Dr. Vicenzi discusses her research on bone marrow aging and its implications for cancer treatment and healthy aging.
Biomarkers and Early Diagnosis
* Dr. Vicenzi explains that her lab is focused on discovering biomarkers for hematological disorders, such as multiple myeloma.
* She discusses the importance of detecting changes early to address them before the disease progresses.
* Dr. Vicenzi highlights the potential for personalized treatment approaches based on biomarkers.
Axon Guidance and Neurodevelopmental Disorders
* Dr. Vicenzi explains the process of axon guidance, where neurons sample their environment for cues to determine their connections.
* She discusses her PhD research on serotonin's role in axon guidance and its implications for neurodevelopmental disorders like autism and ADHD.
* Dr. Vicenzi shares her fascination with the complex process of neuronal circuit formation and its impact on behavior.
Dr. Vicenzi's Awards and Contributions
* Dr. Vicenzi mentions her postdoctoral fellowships, including one from the California Institute for Regenerative Medicine.
* She shares her pride in receiving the Japa award for advancing postdoctoral training at UC San Diego.
* Dr. Vicenzi discusses her involvement in creating a podcast to provide a platform for trainees to share their stories and experiences.
Audience Questions and Advice for Students
* Dr. Vicenzi advises students to follow their dreams, be determined, and find a supportive network.
* She emphasizes the importance of gratitude and learning from both good and challenging experiences.
* Dr. Vicenzi shares her belief that she wouldn't change anything in her journey, as it has shaped her into who she is today.
Future of Brain Research and Final Thoughts
* Dr. Vicenzi hopes that brain research will focus on empathy, community, and the strength that comes from belonging.
* She expresses her desire to continue making a positive impact on the scientific community and society.
* Dr. Vicenzi encourages young listeners to be authentic and show up as their best selves in the world.
"The Science Of" is a student-produced podcast. The team members are Kelsey Lewis, Evan Sosa, Max Arola, August Ou, Danielle-Elizabeth Mensah-Baah, Zahraa Munaim, Josue Castillo, Sasha Goldschmied, and Noor Munaim. The students who appeared on this episode and/or produced the episode are Danielle-Elizabeth Mensah-Baah, Zahraa Munaim, Max Arola, Sasha Goldschmied. The episode was engineered / mixed / mastered by Christelle Auzas from Cloudcast Media.
About Cloudcast Media
As the national leader in local podcasting, Cloudcast Media proudly produces "The Science Of" throught its SchoolCAST platform to help amplify, augment, and accelerate the mission and reach of community social impact organizations. For more information on Cloudcast Media, please visit their website at CloudCast Media [https://cloudcastmedia.us/].
About UCSD Moores Cancer Center
Established in 1978, Moores Cancer Center at UC San Diego Health is one of just 57 National Cancer Institute-Designated Comprehensive Cancer Centers in the United States, and the only one in the San Diego region. Such centers are prominent among the leading institutions in the nation dedicated to scientific innovation and clinical excellence. From research in molecular genetics to the most advanced treatments, Moores Cancer Center is at the forefront of the fight against cancer, developing promising new therapies and making them available to cancer patients throughout the region. Our cancer services were ranked #1 in San Diego, with 10 specialties ranking nationally by U.S. News & World Report in its 2023-2024 "Best Hospitals" survey. For more information, please visit https://moorescancercenter.ucsd.edu/ [https://moorescancercenter.ucsd.edu/].
About Jackie Robinson Family YMCA
The Jackie Robinson Family YMCA serves over 20,000 youth and families each year through a wide variety of educational, recreational and sports programs. In one of San Diego's most critical communities, we have a daily opportunity to make a significant impact on thousands of lives. YMCA programs teach kids character values and valuable skills that will help them grow into responsible, successful adults. For more information, please visit https://www.ymcasd.org/locations/jackie-robinson-family-ymca [https://www.ymcasd.org/locations/jackie-robinson-family-ymca].
About the Elementary Institute of Science
The Elementary Institute of Science (EIS) is a nonprofit organization committed to increasing lifelong opportunities for students of southeast San Diego through science, technology, engineering and math (STEM) education. Our after-school, weekend and school partnership programs broaden access to quality STEM experiences, foster critical thinking, expand technical skills and encourage students to pursue STEM careers. For more information, please visit https://eisca.org/ [https://eisca.org/].
The episode was recorded by the students and engineered / mixed / mastered by Christelle Auzas.