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1 episodesMitrix Bio Website: https://www.mitrix.bio/ Contact form on Website Show notes: Personal introduction: Bioreactor-grown mitochondria 8-9 years old field Grow young healthy mitochondrial and transplant them into the cells Had a few software companies on the 1990’s and fusion start-ups Stanford accelerator Lasers Molecular and biological imaging Mito-field is booming The mechanisms of the mitochondria than the biologics of them Gas turbines Little rotating turbines Combust fuel and oxygen That does anything to power the cell The main question: What is aging? Aging is healing, and the loss of the ability to heal The body and cells are not static There is enough rebuilding capacity when you are young As you age, the energy available to rebuild your cells slacks off They can’t replicate as fast Your body can’t afford to maintain large muscles so they shrink “We have made older animals younger…” They just need the higher levels of energy that is lost after youth The theory: texting and repairing mechanisms weaken and don’t have enough energy to do their jobs as effectively The brain and heart don’t decline as fast as the rest of the body The kidneys and skin and muscles decline the fastest Mitochondria are fundamental to all of your cells and organs and muscles 10% of you body weight and generate 90% of your energy in your body Merged a billion years ago with simple-celled organisms Mitochondrial dna You start with One nuclear dna and 500,000 mtDNA 26 major groups of mtDNA As you age the dna acquires copying errors like a computer disk that needs to be cleaned up Mitochondrial energy decline IS aging Hallmarks of aging : Both nuclear dna and mtDNA are decaying and declining You have to replace a car battery, and we should be able to do the same thing with ourselves: the body and car can just keep going…. The cells will scoop up the new mitochondria and use the new fresh free mitochondria 75 years old, you can feel 40-45 years old again Skin will get tighter and muscles will regrow Reversing aging and not just slowing it down Starting with the longevity market / field Most of it is fluff and noise and bubbles that pop We have a bubble because there’s a huge opportunity and a lot of people dive in A lot of billionaires investing Altos Laboratories from Jeff Bezos, Amazon Retro.bio by Sam Altman /Open Ai, ChatGPT New Limit from Brian Armstrong, coinbase Hevolution Project by Saudi Arabia One or two good approaches: Mitochondria transplants Epigentic reprogramming. Future biogenetic mitochondria producing machines in every house as a daily treatment/supplement Holy Fire book Correlation vs causation Secondary and tertiary effects Mitochondria is a primary cause of aging Telomere is secondary or just correlary effect “Allow aging to happen” as a compromise that’s a trade off Famine and intermittent fasting vs caloric restriction The body uses the muscles to funnel to the heart and brain Intermittent feasting Saunas are recommended There are a lot of excesses in the longevity field Lots of vitamins Lots of running More is not always better Minimum effective dose Maximum effective dose Homeostasis
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