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Behind the Slides

Podcast by Scott M. Matson

English

Technology & science

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About Behind the Slides

Behind the Slides is a podcast about the thinking behind modern medicine—how evidence is generated, interpreted, and applied in the real world. Through conversations with leading clinicians, researchers, and thinkers, we go beyond the headlines and publications to explore the reasoning, tradeoffs, and career decisions that shape what we do and why we do it. If you’ve ever wondered what really drives clinical decisions—or how to build a meaningful career in medicine—this is the conversation behind it all.

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4 episodes

episode Adam Mastroianni: Episode 004 artwork

Adam Mastroianni: Episode 004

In this episode of Behind the Slides, Scott Matson sits down with Adam Mastroianni to explore the incentives, institutions, and hidden cultures that shape modern science. Using Adam’s widely discussed essays on scientific publishing, peer review, and the replication crisis as a starting point, the conversation expands into a broader discussion about how scientific systems reward productivity, novelty, and institutional survival—and whether those incentives are compatible with genuine discovery. Topics include: * Why scientific publishing may function more like a prestige economy than a truth-seeking system * The tension between transformational ideas and peer review * Whether NIH-style funding structures inherently favor incrementalism * Science as a “strong-link problem” and concerns about the future pipeline of creative scientists * The apprenticeship nature of scientific training and Adam’s “crock pot” analogy for how scientific culture is absorbed * Why labs may unintentionally reproduce both epistemic virtues and epistemic pathologies * The replication crisis, publication bias, and the incentives surrounding positive findings * Whether modern academia still attracts highly agentic, unconventional thinkers * What kinds of scientific environments actually produce original and rigorous scientists Rather than treating science as a purely rational machine, the discussion examines it as a deeply human system shaped by psychology, incentives, identity, prestige, and culture. Experimental History by Adam Mastroianni: https://www.experimental-history.com [https://www.experimental-history.com/]

14 May 2026 - 55 min
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