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OpenAI Podcast

Podcast by OpenAI

English

Technology & science

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About OpenAI Podcast

Hosted by Andrew Mayne, The OpenAI Podcast features conversations with the people building with and working at OpenAI. Topics range from how new features are developed to what users are doing with the technology. It’s a practical look at how AI is made and where it’s going, told by the people closest to the work. Hosted on Acast. See acast.com/privacy for more information.

All episodes

20 episodes

episode Episode 19 - Inside image generation’s Renaissance moment artwork

Episode 19 - Inside image generation’s Renaissance moment

People are generating over 1.5 billion images a week in ChatGPT. In this episode, Product lead Adele Li and researcher Kenji Hata share some of the new use cases and trends since the launch of Images 2.0. Together with host Andrew Mayne, they trace the progress from the early DALL-E days and dive into the latest capabilities, including better text rendering, photorealism, multilingual support, world knowledge, aspect ratios, and character consistency. They also explore what comes next as image generation models evolve into more capable creative assistants. Chapters 00:36 How Adele and Kenji came to work on Images 02:27 Images 2.0 launch reception 05:25 Productivity use cases and and 360 images 09:34: Viral trends, authenticity, and imperfection 10:51 Training breakthroughs and photorealism 14:06 Evals, prompting, and creative control 22:16 Creative agents and what comes next 22:27 Images + Codex 28:08 Prompt tips ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

14 May 2026 - 29 min
episode Episode 18 - Why AI needs a new kind of supercomputer network artwork

Episode 18 - Why AI needs a new kind of supercomputer network

Training frontier models isn’t as simple as adding more GPUs—one small problem and the whole coordinated dance falls apart. OpenAI’s Mark Handley and Greg Steinbrecher discuss how a new supercomputer network design, used to train some of the company’s latest models, keeps the whole system moving in lockstep, even with record numbers of GPUs. They break down Multipath Reliable Connection, a new protocol OpenAI developed with AMD, Broadcom, Intel, Microsoft, and Nvidia, and why they’re making it available for the whole industry to use. Chapters 00:00 Intro 00:39 Greg and Mark's paths to OpenAI 04:34 Why training AI stresses networks differently 10:05 Bottlenecks, failures, and the cost of waiting 15:19 How Multipath Reliable Connection works 18:59 A protocol to route around failures 25:05 Why OpenAI is making MRC an open standard 35:09 Could AI compute move to space? ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

6 May 2026 - 37 min
episode Episode 17 - What happens now that AI is good at math? artwork

Episode 17 - What happens now that AI is good at math?

Math is one of the clearest ways to see how far AI has come in a short span. OpenAI researchers Sébastien Bubeck and Ernest Ryu join host Andrew Mayne to explain what changed and what it could mean for the future of research. They reflect on how Ernest used ChatGPT to help solve a 42-year-old open problem, the difference between deep literature search and original mathematical discovery, and what changes when AI can work over longer timelines.  Chapters 01:27 The surprising progress of AI’s math capabilities  03:01 Solving an open problem with ChatGPT 06:57 How models went from basic math to research level 11:32 Why math matters for AGI 14:26 AI and the Erdős problems 21:26 Building an automated researcher 28:19 The role of humans as models improve 33:52 Verifying proofs with AI 36:00 The risk of shallow understanding 41:19 Advice for learning math with ChatGPT ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

28 Apr 2026 - 43 min
episode Episode 16 - Building AI for Life Sciences artwork

Episode 16 - Building AI for Life Sciences

What does it take to build AI systems that can actually help scientists? Research lead Joy Jiao and product lead Yunyun Wang discuss how OpenAI is developing models for life sciences and what responsible deployment means in a field with real biosecurity stakes. They explore how AI is already improving research workflows and where it could lead in drug discovery and more autonomous labs — including why a future with less pipetting sounds pretty good to most scientists. Chapters 0:39 Introducing the Life Sciences model series 3:47 Joy’s path into life sciences 5:00 Autonomous lab with Ginkgo Bioworks 7:27 Yunyun’s path into life sciences 8:12 OpenAI’s life sciences work 9:48 Biorisk, access, and safeguards 15:43 What models can do in the lab 17:51 Building scientific infrastructure 20:14 Why compute matters for science 24:54 Where are we in 6-12 months? 29:51 Scientific adoption and skepticism 33:17 Advice for students and researchers 40:27 Where are we in 10 years? ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

16 Apr 2026 - 44 min
episode Episode 15 - Inside the Model Spec artwork

Episode 15 - Inside the Model Spec

The more AI can do, the more we need to ask what it should and shouldn’t do. In this episode, OpenAI researcher Jason Wolfe joins host Andrew Mayne to talk about the Model Spec, the public framework that defines intended model behavior. They discuss how the Model Spec works in practice, including how the chain of command handles  conflicts between instructions, and how OpenAI evolves it based on feedback, real-world use, and new model capabilities. Chapters 00:00 Introduction 01:10 What is the Model Spec? 03:55 How does the Model Spec work in practice? 06:26 Transparency: Where to read the Model Spec & give feedback 07:51 How did the Model Spec originate? 10:02 How does the spec translate into model behavior? 11:26 What is the hierarchy / chain of command? 13:35 Handling edge cases like Santa Claus 17:41 How does the Model Spec evolve over time? 19:59 What happens when models disagree with the spec? 22:05 How do smaller models follow the spec? 23:16 Is chain-of-thought useful for alignment? 24:16 Model Spec vs Anthropic’s Constitution 26:28 What surprised you most? 26:56 How do you define the scope of the spec? 27:44 What is the future of the Model Spec? 31:16 How should developers think about the spec? 34:44 Asimov’s laws vs Model Spec 37:16 Could AI write a Human Spec? ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

25 Mar 2026 - 37 min
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