How to slow aging naturally
Interview with Associate Professor Jan Gruber from the National University of Singapore. We discuss practical steps which everyone should consider taking if they wish to stay healthier for longer.
Chapters:
0:00 introduction
1:31 Jan's background
6:50 How Jan's views on the aging process changed in the last 5 years
11:20 Impact of blood pressure on aging
13:48 Truths and myths about anti aging supplements
19:00 Key biomarkers of aging
22:00 Benefits of fasting for longevity
24:00 Biomarkers and biological age, biological clock
33:00 Practical recommendations to improve mitochondrial function
35:00 Ora Biomedical and 1M Molecule Challenge
The million molecule challenge: https://orabiomedical.com/sponsor-mmc/ - sponsor your own anti aging drug and get it named after you
Preprint of the paper in the Nature Aging about biological clock https://www.medrxiv.org/content/10.1101/2023.07.14.23292604v1
Associate Professor Jan Gruber is currently an Associate Professor at Yale-NUS. Before his appointment, he was a Senior Research Fellow in the Neurobiology and Ageing Programme at the Centre for Life Sciences (CeLS), National University of Singapore (NUS). From 1995 to 1998, Assoc Prof Gruber studied physics at the RWTH-Aachen University (Germany) before reading Part III of the Mathematical Tripos (MASt) at the University of Cambridge (UK). From 1999 to 2004, Assoc. Prof. Gruber was a graduate student in the Laboratory of Molecular Biophysics, Department of Biochemistry at Oxford University (UK). There, he worked on cell division cycle control, protein-protein interaction characterisation and rational drug design, first obtaining a MSc and later a PhD in molecular biophysics. During his PhD work, he also developed and implemented functionality for ccp4mg, a widely used molecular graphics package (freely available from: www.ccp4mg.ac.uk). ccp4mg enables macromolecular visualisation, scientific illustration and structure-based drug design.In addition to teaching and mentoring students in the laboratory, Assoc Prof Gruber has lectured at NUS since 2007 on free radical biology and medicine, evolutionary and molecular aspects of ageing and clinical biomarker analysis. He has also been involved in teaching students critical evaluation of primary literature. He regularly hosts attachment, visiting, outreach and international project students. In addition to teaching and training students of all levels and from diverse backgrounds, in ageing and general biochemical and laboratory techniques, Assoc Prof Gruber regularly supervises and co-supervises PhD, honours and interdisciplinary attachment students.
Dr. Chong He received her PhD in Biochemistry from Peking University. She then conducted the molecular biology of aging research at the Buck Institute in the US, where she successfully discovered ibuprofen, a common over-the-counter drug used to relieve pain and fever, extended the lifespan in lab animals. She is now working at a pharmaceutical company as a lead scientist on several biotherapeutic drug development projects.
Dr. Dmitri Konash is a Computer Science PhD and former Intel Corp executive. He is a founder of the blood pressure app BreathNow and @breathnow_app YouTube channel which helps users to lower anxiety and blood pressure with natural tools. Dmitri is an active master athlete and multiple Ironman race finisher.
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