Huberman Lab

Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi

My guest is Dr. Thaïs Aliabadi, MD, board-certified OB/GYN, surgeon and leading expert in women's health. We discuss polycystic ovary syndrome (PCOS) and endometriosis, two very common yet frequently undiagnosed causes of female infertility. Dr. Aliabadi explains the symptoms, underlying causes and evidence-based treatments for both conditions, including supplement and lifestyle interventions. We also discuss breast cancer risk and screening, pregnancy, perimenopause and menopause, and the hormone tests that women should request. This conversation offers empowering, potentially life-changing information for women of all ages to take control of their hormone, reproductive and overall health. Read the episode show notes at hubermanlab.com [https://www.hubermanlab.com/episode/female-hormone-health-pcos-endometriosis-fertility-breast-cancer-thais-aliabadi]. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman [https://drinkagz.com/huberman] Lingo: https://hellolingo.com/huberman [https://hellolingo.com/huberman] Our Place: https://fromourplace.com/huberman [https://fromourplace.com/huberman] Joovv: https://joovv.com/huberman [https://joovv.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] Function: https://functionhealth.com/huberman [https://functionhealth.com/huberman] Timestamps 00:00 Thaïs Aliabadi 02:56 Why Endometriosis & Polycystic Ovary Syndrome (PCOS) Go Undiagnosed 08:16 Infertility, Tool: Early Screening 10:54 Sponsors: Lingo & Our Place 14:07 Women's Health Education Gap 15:24 PCOS Overview: Symptoms, Diagnosis, AMH, Disordered Eating 21:28 Irregular Periods, Teenage PCOS Diagnosis 24:36 Diagnosis, Pelvic Ultrasound; PCOS Naming 27:49 Thinning Hair & Acne; 4 PCOS Phenotypes; Mood & Treatment 35:54 Underlying Pillars of PCOS; HPA Axis, Androgens, Menstruation & Ovulation 40:30 Insulin Resistance & PCOS, Visceral Fat & Inflammation 46:30 Sponsors: AGZ by AG1 & Joovv 49:10 PCOS, Chronic Inflammation, Genetics & Lifestyle; Mood 52:31 PCOS, Fertility, Freezing Eggs, Tool: Egg Count & AMH Range By Age 58:34 Women's Health Education, AI, Clinicians; Cataracts Analogy 1:01:20 Stress; PCOS Treatment, Birth Control, Insulin Resistance & Metformin 1:06:44 PCOS Risk Calculator, Supplements, Lifestyle Factors; GLP-1s 1:12:32 Berberine, Metformin; GLP-1s, Food Anxiety & Alcohol 1:19:13 PCOS Prescriptions & Fertility; PCOS Co-Occurrence with Endometriosis 1:21:56 Sponsor: LMNT 1:23:16 PCOS Treatment, Freezing Eggs, Egg Quality; Advocate For Your Health 1:32:02 PCOS Key Takeaways: Symptoms, Tests, Supplements & Lifestyle 1:36:03 Undiagnosed Endometriosis, Fertility 1:39:26 Endometriosis: Symptoms, Diagnosis, Painful Periods, Infertility 1:42:30 Male vs Female Health Issues, Undiagnosed Endometriosis 1:47:01 Inflammation, Ectopic Implants, Chronic Pelvic Pain; Adenomyosis 1:50:36 Egg Quality, Endometriosis, Tools: Egg Counts; Pelvic Ultrasound 1:54:29 Sponsor: Function 1:56:13 Pain & Health Testing, Tool: Endometriosis Symptoms, Screening & Tests 2:01:32 Treatment, Surgery, Different Types of Endometriosis 2:05:22 Endometriosis Causes, Inflammation; Incidence, PCOS 2:11:58 Obstetrics & Gynecology Separation, Surgery 2:16:00 Endometriosis Key Takeaways: Symptoms, Treatment & Diagnosis 2:17:04 Treatment, Estrogen & Progesterone, Birth Control, GnRH Antagonists 2:22:39 Endometriosis Stage & Pain, Endometriosis Types 2:23:49 Pregnancy; Postpartum Depression, Menopause; Frustration for Patients 2:29:55 Fibroids, Surgery, Uterine Septum, Tool: Pelvic Ultrasound 2:34:05 Tool: Assessing Your & Partner's Fertility; Autoimmune Conditions 2:37:51 Breast Cancer, Tool: Lifetime Risk Calculator & Breast Imaging; Mastectomy 2:49:47 Endometriosis Tests, Autoimmune Disease; Brain Fog & Menopause; Inositol 2:53:06 Undiagnosed Infertility; PMDD Treatment; Fasting & Low-Carbohydrate Diets 2:57:21 Hair Loss & Perimenopause; Egg Quality; Endometriosis & Menopause 3:00:40 Increase Progesterone; Diet, Hormone & Menopause; Prolong Fertility 3:04:54 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners

In this Huberman Lab Essentials [https://www.hubermanlab.com/essentials] episode, I discuss the science of social connection and how we form meaningful bonds with others. I explore the neural basis for "social homeostasis"—our drive for a certain amount of social interaction—which explains why we feel lonely, seek connection and how we navigate social hierarchies. I also explain how the brain and neurochemicals, such as oxytocin and dopamine, shape our relationships from infancy through adulthood and underlie traits like introversion and extroversion. The episode also offers practical insights into forming deeper connections and how shared experiences with others enhance social bonding. Read the episode show notes at hubermanlab.com [https://www.hubermanlab.com/episode/essentials-science-building-strong-social-bonds-family-friends-romantic-partners]. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman [https://drinkagz.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] David: https://davidprotein.com/huberman [https://davidprotein.com/huberman] Timestamps 0:00 Social Connection 1:10 Social Bonds, Social Isolation & Stress Hormones 3:09 Sponsor: LMNT 4:42 Brain & Social Homeostasis; Social Hierarchies & Flexibility 9:14 Dopamine & Pro-Social Behaviors; Chronic Social Isolation & Introversion 11:04 Introverts vs Extroverts, Dopamine & Social Homeostasis; Context 13:08 Loneliness, Dorsal Raphe Nucleus & Social Hunger 14:18 Key Takeaway: Introvert vs Extrovert & Dopamine 15:23 Social Bonds & Physiological Synchrony, Tool: Shared Experiences 18:19 Sponsor: AGZ by AG1 19:48 Right- vs Left-Brained Attachment, Parent & Child, Unconscious Mind 24:30 Friends & Romantic Partners, Emotional & Cognitive Empathy 27:52 Sponsor: David 29:09 Oxytocin & Social Connection 31:39 Tool: Emotional & Cognitive Empathy 32:54 Introverts, Extroverts & Social Interaction 33:48 Break-Ups; Key Takeaways Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

How to Speak Clearly & With Confidence | Matt Abrahams

My guest is Matt Abrahams, lecturer at Stanford Graduate School of Business and a world expert in communication and public speaking. He explains how to speak with clarity and confidence and how to be more authentic in your communication in all settings: public, work, relationships, etc. He shares how to eliminate filler words ("umm"-ing), how to overcome stage fright and how to structure messages in a way that makes audiences remember the information. He also shares how to recover gracefully if you "blank out" on stage and simple drills and frameworks that dramatically improve spontaneity, storytelling and overall communication effectiveness. People of all ages and communication styles will benefit from the practical, evidence-supported protocols Matt shares to help you communicate with greater confidence and impact. Read the episode show notes at hubermanlab.com. Pre-order Andrew's book Protocols: https://go.hubermanlab.com/protocols [https://go.hubermanlab.com/protocols] Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman [https://drinkagz.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] BetterHelp: https://betterhelp.com/huberman [https://betterhelp.com/huberman] Joovv: https://joovv.com/huberman [https://joovv.com/huberman] Mateina: https://drinkmateina.com/pages/store-locator [https://drinkmateina.com/pages/store-locator] Function: https://functionhealth.com/huberman [https://functionhealth.com/huberman] Timestamps (0:00) Matt Abrahams (3:21) Public Speaking Fear, Status; Speech Delivery (5:36) Speech, Connection, Credibility; Authenticity (9:05) Monitoring, Self-Judgement; Memorization, Tool: Object Relabeling Exercise (13:13) Sponsors: Eight Sleep & BetterHelp (15:40) Cadence & Speech Patterns; Lego Manuals, Storytelling & Emotion (19:18) Visual vs Audio Content, Length, Detail (23:19) Understanding Audience's Needs, Tool: Recon – Reflection – Research (24:25) Judgement in Communication, Heuristics (27:33) Questions, Responding to the Audience, Tool: Structuring Information (31:34) Feedback & Observation; Tools: Three-Pass Speech Review; Communication Reflection Journal (39:09) Movement, Stage Fright, Content Expertise (42:54) Sponsors: AGZ by AG1 & Joovv (45:34) Multi-Generation Communication Styles & Trust; Curiosity, Conversation Turns (50:32) Linear vs Non-Linear Speech, Tool: Tour Guide Expectations (53:21) Develop Communication Skills, Audience Size, Tools: Distancing; Practicing (1:01:43) Tool: Improv & Agility; Great Communication Examples; Divided Attention (1:09:36) One-on-One Communication vs Public Speaking (1:11:00) Sponsor: Mateína (1:12:00) Neurodiversity, Introverts, Communication Styles; Writing & Editing (1:16:30) Calculating Risk, Tool: Violating Expectations & Engaging Audience (1:21:20) Authenticity, Strengths, Growth & Improv (1:23:23) Damage Control, Tools: Avoid Blanking Out; Contingency Planning, Silence (1:30:32) Nerves, Tool: Breathwork; Spontaneous Communication; Beta-Blockers (1:34:29) Communication Hygiene, Caffeine, Tools: NSDR/Yoga Nidra; Vestibular System & Sleep (1:40:08) Conversation Before Speaking; Delivering Engaging Speeches (1:42:56) Sponsor: Function (1:44:43) Anticipation, Tool: Introduce Yourself; Connect to Environment, Phones (1:51:30) Customer Service & Kids Jobs; Tool: Role Model Communication; COVID Pandemic (1:56:04) Quiet But Not Shy, Extroverts; Social Media Presence (2:00:25) Martial Arts, Sport, Running, Presence & Connection (2:04:16) Apologizing; Communication Across Accents & Cultures (2:07:36) Interruptions, Tools: Paraphrasing; Speech Preparation (2:10:57) Public Speaking Fear, Tool: Envision Positive Outcome; Arguments & Mediation (2:13:19) Omit Filler Words, Tool: Landing Phrases; Time & Storytelling (2:16:52) Asking For a Raise; Poor Communicators & Curiosity; Memorization (2:19:49) Pre-Talk Anxiety Management; Acknowledgements (2:23:47) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman

In this Huberman Lab Essentials [https://www.hubermanlab.com/essentials] episode, my guest is Dr. Jack Feldman, PhD, a Distinguished Professor of Neurobiology at the University of California, Los Angeles, and a leading expert in the science of breathing. We explain the mechanics of breathing and the neural circuits that generate and regulate our breathing rhythm. We also discuss how breathing patterns profoundly influence mental states, including their role in reducing anxiety and enhancing emotional resilience. Dr. Feldman also shares practical tools, such as box breathing for daily performance and magnesium L-threonate supplementation to support cognitive health and longevity. Read the episode show notes at hubermanlab.com [https://www.hubermanlab.com/episode/essentials-breathing-mental-physical-health-performance-jack-feldman]. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman [https://drinkagz.com/huberman] Mateina: https://drinkmateina.com/huberman [https://drinkmateina.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] Timestamps 00:00:00 Jack Feldman 00:00:23 Breathing Mechanics, Diaphragm; Pre-Bötzinger Complex & Breath Initiation 00:03:25 Nose vs Mouth Breathing 00:04:23 Sponsor: Mateina 00:05:24 Active Expiration & Brain; Retrotrapezoid Nucleus 00:08:32 Diaphragm & Evolution; Lung Surface Area & Alveoli, Oxygen Exchange 00:12:56 Diaphragmatic vs Non-Diaphragmatic Breathing 00:14:23 Physiological Sighs: Frequency & Function; Polio & Ventilators 00:18:21 Sponsor: AGZ by AG1 00:19:52 Drug Overdose, Death & Gasps 00:21:38 Meditation, Slow Breathing & Fear Conditioning Study 00:25:28 Mechanistic Science in Breathwork Validation; Breath Practice & Reduced Fear 00:27:21 Breathing & Emotional/Cognitive State, Olfaction, Vagus Nerve 00:29:44 Carbon Dioxide, Hyperventilation & Anxiety 00:31:21 Sponsor: Eight Sleep 00:32:47 Breathing, Emotion & Autonomic Processes Coordination; Depression & Breath Practices 00:36:43 Tool: Breathwork Practices, Box Breathing, Tummo, Wim Hof 00:38:46 Magnesium L-Threonate & Cognitive Enhancement; Compound Refinement 00:44:28 Clinical Trial, Magnesium L-Threonate & Cognitive Improvements; Dose, Sleep 00:48:28 Acknowledgements Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

How Your Thoughts Are Built & How You Can Shape Them | Dr. Jennifer Groh

My guest is Dr. Jennifer Groh, PhD, professor of psychology and neuroscience at Duke University. She explains how our brain encodes sights and sounds and integrates them so we can navigate and understand the world around us. She explains what thoughts really are and how what you focus on determines your thoughts, not just in that moment but your future thoughts too. We discuss this in the context of how to improve your level of focus and happiness and how to complete tasks and task-switch more effectively. We also discuss how you can rewire the neural circuits that underlie your default patterns of thinking and attention. Sponsors AGZ by AG1: https://drinkagz.com/huberman [https://drinkagz.com/huberman] Lingo: https://hellolingo.com/huberman [https://hellolingo.com/huberman] Wealthfront*: https://wealthfront.com/huberman [https://wealthfront.com/huberman] Our Place: https://fromourplace.com/huberman [https://fromourplace.com/huberman] Helix Sleep: https://helixsleep.com/huberman [https://helixsleep.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] Timestamps 0:00 Jennifer Groh 3:41 Sounds & Vision, Sensory Integration; Dynamic Maps 7:42 Context & Mapping; Screens, Projection & Perception, Ventriloquists 13:52 Sound Localization 16:53 Sponsors: Lingo & Wealthfront 19:50 Hearing Loss & Sound Localization, Ear Folds 21:56 Unfamiliarity of Hearing Your Own Voice; Tool: Bone Conduction Headphones 26:16 Tool: Headphone Volume & Protecting Hearing 28:57 3D Sound, Sound Distance, Thunder, Earthquakes 37:24 Sound Integration; Sound Frequency & Distance, Warning Signals 44:36 Sponsors: AGZ by AG1 & Our Place 47:39 Music, Rhythm, Community & Emotion 57:00 Music, Military; Courtship; Evolution of Music & Language 1:02:37 Ears, Visual & Auditory Integration, Sound Localization 1:09:48 Evolution of Visual & Auditory Systems, Music; Brain Controlling Vision 1:15:17 Sponsor: Helix Sleep 1:16:45 Physical Space & Sounds; Cathedrals, Sound Delay 1:22:37 Music, Emotion & Community; Science & Admitting Weakness 1:27:01 Thinking & Sensory Simulations; Forming Thoughts 1:33:18 Attention, Attractor States, Flow States, Tool: Changing Environment 1:37:38 Sounds & Environment for Focus, Attention, Tool: Mental Interval Training 1:44:37 Sponsor: LMNT 1:45:58 Endurance & Interval Mental Work; Mental Rest, Music 1:50:37 Musician, Rehearsal & Performance; Pressure 1:54:16 Chickens; Hypnotizing Chickens, Visual Attention & Focus 2:03:47 Relaxation, Phones & Schools, Boredom, Social Media 2:12:48 Acknowledgements 2:13:58 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Protocols Book, Social Media, Neural Network Newsletter *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC.  Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]