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A potential new breakthrough could impact how people suffering from a condition called chronic ocular surface pain receive treatment. A newly published clinical trial in the journal Ophthalmology and Therapy has revealed that a novel, handheld cooling device could offer lasting relief without the use of medication. The multicenter, double-masked study evaluated a single, four-minute in-office treatment developed by EyeCool Therapeutics, and the results suggest a significant shift in how this chronic pain might be managed in the future. The trial followed patients for eight weeks and found that the localized cooling therapy produced durable, clinically meaningful reductions in eye pain. Remarkably, it also statistically improved corneal sensitivity, which is frequently degraded in those suffering from the condition. The treatment proved particularly effective for patients with "peripheral-dominant" pain—meaning the chronic discomfort is rooted directly in the nerves on the eye’s surface, rather than within the central nervous system. Importantly for safety, the device was well-tolerated, with no serious adverse events reported—the most common side effect being an entirely temporary redness of the eye. Lead author Dr. Anat Galor, from the Bascom Palmer Eye Institute, noted that this technology addresses a critical unmet need for a patient population that currently has very few effective medical options. While the device remains investigational, experts are hailing these findings as a pivotal milestone toward providing a precise, non-pharmacological lifeline for a deeply uncomfortable and frustrating condition.
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