History Taking
A doctor cultures a batch of bacteria and drinks it — not on a dare, but because no ethics committee or journal would let him prove his theory any other way. In the early 1980s, Australian physician Barry Marshall was convinced a curved microorganism called Helicobacter pylori caused peptic ulcers. The medical establishment disagreed: stomachs were too acidic for bacteria, and ulcers were a stress problem, not an infection. So Marshall infected himself, developed gastritis within days, and cured it with antibiotics. The discovery that earned him and pathologist Robin Warren a 2005 Nobel Prize didn't just change treatment — it exposed how deeply medicine can resist evidence when entire careers are built on the wrong answer.
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