33: What Actually Moves Your Cholesterol (And Why It's Probably Not Saturated Fat) Part 2

33: What Actually Moves Your Cholesterol (And Why It's Probably Not Saturated Fat) Part 2

Last week I told you that the 6% saturated fat guideline is not what it appears to be. This week we get into the part that actually matters: what does the research say really moves your cholesterol numbers? This episode lives in the Fuel pillar of the Perimenopause Matrix. Fuel is about how your body uses energy, and for a lot of women in perimenopause, the lipid picture is one of the first places the Fuel pillar starts to signal. I put every major lever side by side with real numbers: saturated fat restriction, psyllium fiber, oat beta-glucan, and statins. I walk through the two key trials in detail, including one where the same dietary change caused a 54-point LDL drop in some people and a 30-point rise in others. I explain why LDL-C and ApoB do not always tell the same story, and why that gap matters for 20 to 30% of women. And I share my own experiment, including the part where doing everything right made my LDL go up by over 30 points. What you will learn: * The LDL-C versus ApoB distinction and why it changes how you read your lipid panel * How the RISSCI-1 and GET-READI trials actually performed, including the findings that rarely get mentioned * How fiber, exercise, and saturated fat restriction compare head to head * What the Fuel pillar framework tells us about lipid management in perimenopause * How to run a clean personal experiment to find out how your body actually responds This is Part 2 of a two-part series. Listen to Episode 32 first. 👉 ⁠Full Episode Show Notes⁠ [https://meganpfiffnernutrition.com/metabolic-health/33-what-actually-moves-your-cholesterol-and-why-its-not-what-youve-been-told-part-2/] About the Perimenopause Matrix:The Matrix is my framework for navigating perimenopause across 6 pillars: Fuel, Move, Recharge, Regulate, Connect, and Clean. But this episode isn't about optimizing all 6 - it's about choosing the ONE that matters most in YOUR current reality. 🧬 Ready to stop guessing? I help women interpret their labs so they can make nutrition decisions based on data, not diet trends. 👉 Book your personalized Lab Review here [https://meganpfiffnernutrition.com/product/lab-review/] 🎁 FREE RESOURCE: Download the free Perimenopause Decoder [https://meganpfiffnernutrition.com/?ff_landing=23] . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos. 📱 CONNECT WITH ME: Website [https://www.notion.so/www.meganpfiffnernutrition.com] ⁠ [https://www.notion.so/www.meganpfiffnernutrition.com]⁠Instagram⁠ [https://www.instagram.com/megan.pfiffner/] ⁠LinkedIn [https://www.linkedin.com/in/meganpfiffner/] ⁠ [https://www.linkedin.com/in/meganpfiffner/]Facebook [https://www.facebook.com/morningswithmegan%E2%81%A0] ⁠ [https://www.facebook.com/morningswithmegan%E2%81%A0]Youtube [https://www.youtube.com/@meganpfiffner] You're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again. Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday! Apple [https://www.notion.so/Podcast-Mornings-with-Megan-8aea54c48e20429088a1f0d72ab18617?pvs=21] Spotify [https://www.notion.so/Jenna-Owsianik-2f06cf200c2a8041b75ccf5e8dd9e6ba?pvs=21] Amazon [https://www.notion.so/2206cf200c2a8037ad4dc0313fcf0552?pvs=21] Youtube [https://www.youtube.com/@meganpfiffner]

32: I Tried to Eat 6% of My Diet From Saturated Fat for a Week and This Is What Happened Part 1

I failed before lunch on day one. And I did not eat a single thing on the American Heart Association's high-saturated-fat restricted list. This is Part 1 of a two-part series sitting in the Fuel pillar of the Perimenopause Matrix. Fuel is about how your body uses energy, and for a lot of women in perimenopause, the lipid picture is one of the first places the Fuel pillar starts to signal. In this episode I walk through why the 6% saturated fat target is harder to hit than anyone tells you, where that number actually came from, and why almost all of the research behind it was conducted in men. I break down the AHA's own math using their own recommended foods, look at the two key trials that came closest to the target, and share the data on who was actually in the foundational research behind these guidelines. 👉 Full Episode Show Notes [https://meganpfiffnernutrition.com/metabolic-health/32-i-tried-to-eat-6-of-my-diet-from-saturated-fat-for-a-week-and-this-is-what-happened-part-1/] What you will learn: * The difference between LDL-c and ApoB, in plain language, and why it matters for the 20% of women where they diverge * Why the 2013 AHA guidelines acknowledge in their own rationale that the studies behind the 6% target did not isolate saturated fat as a variable * How olive oil and walnuts can blow your daily budget before your first meal is finished * What the RISSCI-1 and GET-READI trials actually showed, including the findings that rarely get cited * Why the Women's Health Initiative, the largest dietary trial ever conducted in postmenopausal women, moved LDL by 3.55 points over 8 years with no significant cardiovascular effect This is Part 1 of a two-part series. Part 2 drops next week with the full data comparison and my personal experiment results. 🧬 Ready to stop guessing? I help women interpret their labs so they can make nutrition decisions based on data, not diet trends. 👉 Book your personalized Lab Review here [https://meganpfiffnernutrition.com/product/lab-review/] 🎁 FREE RESOURCE: Download the free Perimenopause Decoder [https://meganpfiffnernutrition.com/?ff_landing=23] . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos. 📱 CONNECT WITH ME: Website ⁠ [https://www.notion.so/www.meganpfiffnernutrition.com]⁠ [https://www.instagram.com/megan.pfiffner/] Instagram⁠ [https://www.instagram.com/megan.pfiffner/] ⁠LinkedIn [https://www.linkedin.com/in/meganpfiffner/] ⁠ [https://www.linkedin.com/in/meganpfiffner/]Facebook [https://www.facebook.com/morningswithmegan%E2%81%A0] ⁠ [https://www.facebook.com/morningswithmegan%E2%81%A0]Youtube [https://www.youtube.com/@meganpfiffner] You're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again. Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday! Apple [https://www.notion.so/Podcast-Mornings-with-Megan-8aea54c48e20429088a1f0d72ab18617?pvs=21] Spotify [https://www.notion.so/Jenna-Owsianik-2f06cf200c2a8041b75ccf5e8dd9e6ba?pvs=21] Amazon [https://www.notion.so/2206cf200c2a8037ad4dc0313fcf0552?pvs=21] Youtube [https://www.youtube.com/@meganpfiffner]

31: The Conversation Your Doctor Never Had with You | Dr. Sarah Berg, OB-GYN

This is the conversation most women never get in a doctor's office. I sat down with Dr. Sarah Berg, a board-certified OB-GYN and Certified Menopause Practitioner, to talk about what is actually happening in your body during the perimenopause transition, why your doctor may not have had the tools to help you even when they wanted to, and what changed when the FDA removed the black box warning from hormone therapy in November 2025. In this episode we cover: * The slope shoulder moment: what Dr. Berg saw happening to her patients, and why it stopped her in her tracks * Why estrogen is not just a reproductive hormone, and how it affects your brain, joints, and genitourinary system * Why most OB-GYNs received fewer than four lectures on menopause during training, and what that means for your care * The Women's Health Initiative study: what it actually showed, and why the headlines got it so wrong * The difference between vaginal estrogen and systemic hormone therapy, and why Dr. Berg says vaginal estrogen is for every woman * The estrogen patch shortage: why it is happening, and what it says about how little the medical system has invested in women's health * Three things every woman navigating perimenopause needs to know right now This episode connects to the Regulate and Connect pillars of the Perimenopause Matrix. Understanding the biology behind your symptoms is the foundation of breaking the shame spiral and getting the care you deserve. 👉 ⁠Full Episode Show Notes⁠ [https://meganpfiffnernutrition.com/hormone-health/31-the-conversation-your-doctor-never-had-with-you-dr-sarah-berg-ob-gyn/] Find Dr. Sarah Berg: Selfority [https://www.selfority.com/]@selfority [https://www.instagram.com/selfority/] Substack [https://sarahbergmd.substack.com/] About the Perimenopause Matrix:The Matrix is my framework for navigating perimenopause across 6 pillars: Fuel, Move, Recharge, Regulate, Connect, and Clean. But this episode isn't about optimizing all 6 - it's about choosing the ONE that matters most in YOUR current reality. 🧬 Ready to stop guessing? I help women interpret their labs so they can make nutrition decisions based on data, not diet trends. 👉 Book your personalized Lab Review here [https://meganpfiffnernutrition.com/product/lab-review/] 🎁 FREE RESOURCE: Download the free Perimenopause Decoder [https://meganpfiffnernutrition.com/?ff_landing=23] . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos. 📱 CONNECT WITH ME: Website⁠ [https://www.notion.so/www.meganpfiffnernutrition.com] ⁠Instagram [https://www.instagram.com/megan.pfiffner/] ⁠ [https://www.instagram.com/megan.pfiffner/]⁠LinkedIn [https://www.linkedin.com/in/meganpfiffner/] ⁠ [https://www.linkedin.com/in/meganpfiffner/]Facebook [https://www.facebook.com/morningswithmegan%E2%81%A0] ⁠ [https://www.facebook.com/morningswithmegan%E2%81%A0]Youtube [https://www.youtube.com/@meganpfiffner] You're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again. Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday! Apple [https://www.notion.so/Podcast-Mornings-with-Megan-8aea54c48e20429088a1f0d72ab18617?pvs=21] Spotify [https://www.notion.so/2f06cf200c2a8041b75ccf5e8dd9e6ba?pvs=21] Amazon [https://www.notion.so/2206cf200c2a8037ad4dc0313fcf0552?pvs=21] Youtube [https://www.youtube.com/@meganpfiffner]

30: IT Just Got a Whole Lot Better - Vaginal Estrogen, the FDA, and What Changes Now Part 3

Episode 30: IT Just Got a Whole Lot Better -- Vaginal Estrogen, the FDA, and What Changes Now This is the finale of my three-part series on sexual health in perimenopause, and the episode I have been most excited to record. We are going deep on vaginal estrogen: what it is, what it does, the history that kept millions of women away from it, what changed in November 2025, and what is coming next with the FDA push to make it available over the counter. What we cover: * The anatomy of the vulva and vagina, why both are estrogen-sensitive, and why knowing the correct vocabulary matters for your healthcare conversations * What vaginal discharge and cervical mucus are, why they are normal, and why your vagina does not need internal cleansing products * Why scented vaginal products are a problem, not a solution * What Genitourinary Syndrome of Menopause (GSM) is and why it is progressive if not addressed * Genitourinary Syndrome of Lactation and why postpartum people may also benefit from this conversation * Two client stories that illustrate very different entry points into the vaginal estrogen conversation * How vaginal estrogen works, what forms it comes in, and why it does not affect blood estrogen levels * Why local vaginal estrogen reduces UTI risk by more than 50 percent * The history of the FDA black box warning and why it was removed in November 2025 * Who can use vaginal estrogen, including breast cancer survivors, and how to have the conversation with your provider * My personal story with vaginal estrogen and how quietly GSM can develop without you noticing This episode lives in the Connect pillar of the Perimenopause Matrix. The FDA removed the black box warning from low-dose vaginal estrogen in November 2025. The research is clear. The tools exist. You deserve a provider who knows about them. Part 1: Let's Talk About IT, Baby [https://meganpfiffnernutrition.com/mental-emotional-health/28-lets-talk-about-it-baby-whats-actually-happening-in-your-body-part-1/] is out now.Part 2: Now Let's Do Something About IT [https://meganpfiffnernutrition.com/mental-emotional-health/29-now-lets-do-something-about-it-your-sexual-health-toolkit-for-perimenopause-part-2/] is out now. 👉 Full show notes and resources [https://meganpfiffnernutrition.com/mental-emotional-health/30-it-just-got-a-whole-lot-better-vaginal-estrogen-the-fda-and-what-changes-now-part-3/] About the Perimenopause Matrix:The Matrix is my framework for navigating perimenopause across 6 pillars: Fuel, Move, Recharge, Regulate, Connect, and Clean. But this episode isn't about optimizing all 6 - it's about choosing the ONE that matters most in YOUR current reality. 🧬 Ready to stop guessing? I help women interpret their labs so they can make nutrition decisions based on data, not diet trends. 👉 Book your personalized Lab Review here [https://meganpfiffnernutrition.com/product/lab-review/] 🎁 FREE RESOURCE: Download the free Perimenopause Decoder [https://meganpfiffnernutrition.com/?ff_landing=23] . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos. 📱 CONNECT WITH ME: Website⁠ [https://www.notion.so/www.meganpfiffnernutrition.com]⁠ [https://www.instagram.com/megan.pfiffner/] Instagram [https://www.instagram.com/megan.pfiffner/] ⁠ [https://www.instagram.com/megan.pfiffner/]⁠LinkedIn [https://www.linkedin.com/in/meganpfiffner/] ⁠ [https://www.linkedin.com/in/meganpfiffner/]Facebook [https://www.facebook.com/morningswithmegan%E2%81%A0] ⁠ [https://www.facebook.com/morningswithmegan%E2%81%A0]Youtube [https://www.youtube.com/@meganpfiffner] You're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again. Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday! Apple [https://www.notion.so/Podcast-Mornings-with-Megan-8aea54c48e20429088a1f0d72ab18617?pvs=21] Spotify [https://www.notion.so/2f06cf200c2a8041b75ccf5e8dd9e6ba?pvs=21] Amazon [https://www.notion.so/2206cf200c2a8037ad4dc0313fcf0552?pvs=21] Youtube [https://www.youtube.com/@meganpfiffner]

29: Now Let's Do Something About IT - Your Sexual Health Toolkit for Perimenopause Part 2

This is part two of my three-part series on sexual health in perimenopause, and this week we are getting practical. Part one was about understanding what is happening in your body. This episode is the toolkit. We cover everything from solo sex as a health practice to the lubrication conversation most women have never had clearly enough, and everything in between. What we cover: * Why solo sex is a body literacy tool and one of the most useful diagnostic practices in perimenopause * What chore play is and why the nervous system needs to feel safe and supported before it can access desire * The myth of spontaneous sex and why scheduling intimacy is more intimate than leaving it to chance * The 0-10 rating scale as a simple, pressure-free communication framework for desire * What osmolality is and why popular lubricants like KY Jelly and Astroglide may be making vaginal dryness worse * Which lubricants actually work with your tissue rather than against it * How toys can support exploration and partnered connection in midlife * A clear framework for knowing when to address changes yourself and when to involve your provider This episode lives in the Connect pillar of the Perimenopause Matrix. Your sex life does not have to wind down in perimenopause. Your body is changing. That is not the same thing as it being over. This episode gives you the tools to work with it. Part 1: Let's Talk About IT, Baby is out now [https://meganpfiffnernutrition.com/mental-emotional-health/28-lets-talk-about-it-baby-whats-actually-happening-in-your-body-part-1/].Part 3: IT Just Got a Whole Lot Better drops next week. 👉 Full show notes and resources [https://meganpfiffnernutrition.com/mental-emotional-health/29-now-lets-do-something-about-it-your-sexual-health-toolkit-for-perimenopause-part-2/] About the Perimenopause Matrix:The Matrix is my framework for navigating perimenopause across 6 pillars: Fuel, Move, Recharge, Regulate, Connect, and Clean. But this episode isn't about optimizing all 6 - it's about choosing the ONE that matters most in YOUR current reality. 🧬 Ready to stop guessing? I help women interpret their labs so they can make nutrition decisions based on data, not diet trends. 👉 Book your personalized Lab Review here [https://meganpfiffnernutrition.com/product/lab-review/] 🎁 FREE RESOURCE: Download the free Perimenopause Decoder [https://meganpfiffnernutrition.com/?ff_landing=23] . It helps you understand what's happening during perimenopause so you can make decisions from a place of clarity, not chaos. 📱 CONNECT WITH ME: Website⁠ [https://www.notion.so/www.meganpfiffnernutrition.com] ⁠Instagram⁠ [https://www.instagram.com/megan.pfiffner/]⁠ [https://www.linkedin.com/in/meganpfiffner/] LinkedIn⁠ [https://www.linkedin.com/in/meganpfiffner/] Facebook ⁠ [https://www.facebook.com/morningswithmegan%E2%81%A0] Youtube [https://www.youtube.com/@meganpfiffner] You're not crazy. You're not broken. You're not alone. And you absolutely deserve to feel like yourself again. Listen to Mornings with Megan Podcast 🎧 New episodes drop every Wednesday! Apple [https://www.notion.so/Podcast-Mornings-with-Megan-8aea54c48e20429088a1f0d72ab18617?pvs=21] Spotify [https://www.notion.so/Jenna-Owsianik-2f06cf200c2a8041b75ccf5e8dd9e6ba?pvs=21] Amazon [https://www.notion.so/2206cf200c2a8037ad4dc0313fcf0552?pvs=21] Youtube [https://www.youtube.com/@meganpfiffner]