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đ Episode Description:What if the secret to preventing cancer isn't more treatmentâbut less growth?In this episode, Vic explores two groundbreaking studies that link low IGF-1 levels to lower cancer and diabetes risk. The first follows a unique village in Ecuador where a rare genetic condition virtually eliminates cancer. The second reveals how low protein intake (especially animal protein) suppresses IGF-1 and reduces mortality in people under 65.We also break down Dr. Valter Longoâs science-backed protocols from The Longevity Diet, including:When to lower or increase protein intakeWhy fasting can helpâor hurtâdepending on how itâs doneWhat types of fish are safest and healthiestHow to protect muscle mass and extend healthspan after 50đ Recommended BookThe Longevity Diet by Dr. Valter Longo, PhDA must-read on how to eat and fast for long-term health, backed by 30 years of biochemistry and gerontology research. Dr. Longo introduces the Fasting Mimicking Diet (FMD), outlines IGF-1 suppression protocols, and shows how diet can prevent or delay age-related diseases like cancer and diabetes.đ Buy on Amazonđ Learn more from Valter Longođ§Ź Protein Intake Recommendations (Dr. Longo)đ¶ Under Age 65 (Cancer Prevention + Longevity)0.31â0.36 g/lb (0.68â0.8 g/kg body weight)150 lb adult â ~47â54g protein/dayđ” Age 65 and Older (Muscle Preservation)0.45â0.55 g/lb (1.0â1.2 g/kg body weight)150 lb adult â ~68â83g protein/dayđ Summary TableAge Group g/lb Body Weight g/kg Body Weight 150 lb ExampleUnder 65 0.31â0.36 0.68â0.8 ~47â54 g/day65 and older 0.45â0.55 1.0â1.2 ~68â83 g/dayđ„ Preferred Protein SourcesLentils, chickpeas, black beansWalnuts, flax, hemp, almondsQuinoa, buckwheatFermented dairy (aged cheese, yogurt â moderate)Low-mercury fish (2â3x/week)Eggs (moderate)Red meat (limit to 2â3x/week or less)đ Low-Mercury Fish Guideâ Best Choices (Low Mercury, High Omega-3)Wild-caught salmon (especially Alaskan)SardinesAnchoviesHerringAtlantic or Pacific mackerel (NOT king)Rainbow troutTilapia, catfish, pollock, whitefishâ ïž Limit These to Once Weekly:Tuna (especially albacore, yellowfin)Halibut, grouper, snapper, Chilean sea bassâ Avoid (High Mercury):King mackerelSharkSwordfishTilefish (Gulf of Mexico)Marlinđ Sources: FDA/EPA Fish Guidelines, Valter Longoâs The Longevity Diet, Environmental Defense Fund Seafood Guideđ Scientific Studies Cited1. Low Protein, IGF-1, and MortalityTitle: Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older populationAuthors: Morgan E. Levine et al.Journal: Cell Metabolism, 2014đ PubMed Link2. Ecuador Study on Growth Hormone Receptor DeficiencyTitle: Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansAuthors: Jamie Guevara-Aguirre et al.Journal: Science Translational Medicine, 2011đ PubMed Linkđ Final TakeawaysLower IGF-1 = lower cancer risk and slower agingUnder 65? Eat less protein, mostly from plantsOver 65? Eat more protein to maintain muscle and strengthDonât fast aggressively without guidance â use structured approaches like FMDEat more fish, vegetables, legumes â and protect muscle mass as you ageâDonât fast just to fast. Donât overeat protein just to bulk. Longevity is about balance.â â Vic
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