
Dementia Matters
Podcast af Wisconsin Alzheimer‘s Disease Research Center
Dementia Matters is a podcast about Alzheimer‘s disease and other causes of dementia. Creator and host Dr. Nathaniel Chin interviews leading scientist...
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202 episoder
Dementia diagnoses affect families in many different ways. One of the most challenging to navigate is that of younger-onset dementia (YOD), a form of dementia that affects someone below the age of 65. This diagnosis can be particularly jarring for young families, as resources, support and research for this form of dementia are limited. When Diana Cose’s husband Lorenzo received this diagnosis, she decided to change that by founding Lorenzo’s House, a nonprofit that supports families grappling with younger-onset dementia and works toward lessening the stigma surrounding it. Diana Cose joins the podcast with programs lead Patti LeFleur to share their experiences with younger-onset dementia and how Lorenzo’s House brings light in the darkness. Guests: Diana Cose, founding executive director, Lorenzo’s House, Patti LeFleur, youth and lighthouse outreach lead, Lorenzo’s House Show Notes Learn more about Lorenzo’s House and their free programs on their website [https://lorenzoshouse.org/]. Follow Lorenzo’s House on their Instagram [https://www.instagram.com/lorenzos_house/], Facebook [https://www.facebook.com/lorenzoshouseofficial/] and LinkedIn [https://www.linkedin.com/company/lorenzos-house/] for updates and more information. Learn about early-onset dementia, mentioned by Dr. Chin at 27:30, listen to our episode with Dr. Susanne Seeger, “Early-onset Alzheimer’s Disease: What to Know and What to Expect [https://www.adrc.wisc.edu/dementia-matters/early-onset-alzheimers-disease-what-know-and-what-expect]” on our website. Learn more about the documentary on autosomal dominant Alzheimer’s disease, mentioned by Dr. Chin at 28:05, on CBS News’ website [https://www.cbsnews.com/amp/news/60-minutes-alzheimers-disease-medellin-colombia-lesley-stahl/] and watch the documentary on Paramount+ [https://www.paramountplus.com/shows/video/6qXFC7Z577n3hmm1MTbKDMC75o3YK2G7/?ftag=CNM-00-10abb6c]. Connect with us Find transcripts and more at our website [https://www.adrc.wisc.edu/dementia-matters]. Email Dementia Matters [dementiamatters@medicine.wisc.edu]: dementiamatters@medicine.wisc.edu Follow us on Facebook [https://www.facebook.com/wisconsinadrc] and Twitter [https://twitter.com/WisconsinADRC]. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter [https://www.adrc.wisc.edu/newsletter]. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. All donations go toward outreach and production.

What exactly does a mild cognitive impairment (MCI) diagnosis mean, and what should you do after receiving one? Hearing this diagnosis from a doctor can bring up a lot of emotions and questions for individuals and family members. Jennifer McAlister joins Dementia Matters to offer advice for next steps after receiving an MCI diagnosis and share strategies and resources that have been successful for individuals she’s worked with over the course of her career. Guest: Jennifer McAlister, outreach and partnerships manager, Outreach, Recruitment & Engagement Core, Wisconsin Alzheimer’s Disease Research Center Show Notes Find Jen’s “Next Steps After Diagnosis” flowchart, mentioned at 41:22, on our website [https://www.adrc.wisc.edu/diagnosis-next-steps] and as a PDF [https://www.adrc.wisc.edu/sites/default/files/2025-01/MCIEarly%20Stage%20Flowchart-Jan282025.pdf]. View and download a PDF of the decision-making tool [https://www.adrc.wisc.edu/sites/default/files/2025-01/Decision%20Making%20Tool.pdf], mentioned at 28:57, online. Learn more about the Wisconsin ADRC’s Healthy Living with Mild Cognitive Impairment (MCI) series on our website [https://www.adrc.wisc.edu/mci]. Watch the Healthy Living with MCI series on YouTube [https://www.youtube.com/playlist?list=PLMkCvbIiRBFcabxhowsOHJK6LQuVf_UJo]. Learn more about MCI by listening to our past podcast episode, “Our Evolving Understanding of Mild Cognitive Impairment [https://www.adrc.wisc.edu/dementia-matters/our-evolving-understanding-mild-cognitive-impairment]” on our website, Spotify [https://open.spotify.com/episode/33PIG1UlvsmdIZIDqwDSUM?si=682f4630572946a7], Apple Podcasts [https://urldefense.com/v3/__https://podcasts.apple.com/us/podcast/our-evolving-understanding-of-mild-cognitive-impairment/id1292353638?i=1000600849775__;!!Mak6IKo!NImdpsygNZl1Yo7VQY7ispvBjujpHy6BH20q9oGoW24w5GoniHv3wGAmAmpX2Gha4pYw1kHVU8m10tOS-r9YKnNqrZ4$], and all podcast platforms. Connect with us Find transcripts and more at our website [https://www.adrc.wisc.edu/dementia-matters]. Email Dementia Matters [dementiamatters@medicine.wisc.edu]: dementiamatters@medicine.wisc.edu Follow us on Facebook [https://www.facebook.com/wisconsinadrc] and Twitter [https://twitter.com/WisconsinADRC]. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter [https://www.adrc.wisc.edu/newsletter]. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. All donations go toward outreach and production.

While there are many kinds of dementia, like Alzheimer’s disease and Lewy body dementia, there’s one that researchers have only recently identified. LATE, or Limbic-predominant Age-related TDP-43 Encephalopathy, is a newly-characterized type of dementia associated with abnormal clumps of a protein called TDP-43. So, what exactly do we know about LATE? Dr. David Wolk joins the podcast to share what key features of LATE are, how it compares to Alzheimer’s disease and impacts treatment, and what next steps are needed to better understand this neurodegenerative disease. Guest: David Wolk, MD, director, Penn Alzheimer’s Disease Research Center, co-director, Penn Memory Center, co-director, Penn Institute on Aging, chief, Division of Cognitive Neurology, professor of neurology, University of Pennsylvania Perelman School of Medicine Show Notes Learn more about LATE on the National Institute on Aging’s website [https://www.nia.nih.gov/health/alzheimers-and-dementia/what-limbic-predominant-age-related-tdp-43-encephalopathy-late] and on Penn Memory Center’s website [https://pennmemorycenter.org/education-and-support-resources/understanding-my-diagnosis/limbic-predominant-age-related-tdp-43-encephalopathy-late/]. Read Dr. Wolk's article, "Clinical criteria for limbic-predominant age-related TDP-43 encephalopathy [https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14202]," on the journal Alzheimer's & Dementia's website. Learn more about Dr. Wolk in his profile on the Penn Memory Center website [https://pennmemorycenter.org/who-we-are/staff/david-wolk-md/]. Connect with us Find transcripts and more at our website [https://www.adrc.wisc.edu/dementia-matters]. Email Dementia Matters [dementiamatters@medicine.wisc.edu]: dementiamatters@medicine.wisc.edu Follow us on Facebook [https://www.facebook.com/wisconsinadrc] and Twitter [https://twitter.com/WisconsinADRC]. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter [https://www.adrc.wisc.edu/newsletter]. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. All donations go toward outreach and production.

The holidays can be a stressful time for everyone, especially those with dementia and their care partners. In preparation for this season, Dr. Alexis Eastman joins Dementia Matters for our last episode of 2024. Drs. Chin and Eastman discuss strategies for managing the potential stress of holiday traveling and gatherings, important safety considerations and more. Guest: Alexis Eastman, MD, geriatrician, Senior Medical Director of Ambulatory Medical Specialties, UW Health, associate clinical professor, Division of Geriatrics and Gerontology, University of Wisconsin School of Medicine and Public Health Show Notes Listen to our past episode with Dr. Eastman, “Holiday Tips for Dementia Caregivers [https://www.adrc.wisc.edu/dementia-matters/holiday-tips-dementia-caregivers],” on our website. Find more resources and tips for the holidays in “Resources for navigating the holidays with Alzheimer’s [https://www.adrc.wisc.edu/news/resources-navigating-holidays-alzheimers]” on our website. Want to support Dementia Matters? Make an end-of-year gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. [https://urldefense.com/v3/__https://www.beingpatient.com/christmas-holidays-dementia-care-expert-guide/__;!!Mak6IKo!IAresesZgq8RP5WFei_6EqxQsKLO8WC4Z5hsP0wh4VCCPMlsTiulyE5wNB--pMGxdyjzXYQgVdoIOLD68LfAxQ$] Connect with us Find transcripts and more at our website [https://www.adrc.wisc.edu/dementia-matters]. Email Dementia Matters [dementiamatters@medicine.wisc.edu]: dementiamatters@medicine.wisc.edu Follow us on Facebook [https://www.facebook.com/wisconsinadrc] and Twitter [https://twitter.com/WisconsinADRC]. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter [https://www.adrc.wisc.edu/newsletter]. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. All donations go toward outreach and production.

With the recent surge in artificial intelligence and machine learning technology, one of the most exciting fields it could revolutionize is health care and, more specifically, the field of cognitive care and research. Dr. Marina Sirota and Alice Tang join the podcast to share their research on how AI could be used to predict one’s risk of developing Alzheimer’s disease based on their electronic health records. They also discuss what needs to be done to improve these algorithms and other ways this technology could be used in Alzheimer's disease research. Guests: Marina Sirota, PhD, associate professor, University of California San Francisco (UCSF), principal investigator, Sirota Lab, and Alice Tang, MD/PhD student, University of California San Francisco, postdoctoral fellow, Sirota Lab Show Notes Read Alice Tang and Dr. Sirota’s study, “Leveraging electronic health records and knowledge networks for Alzheimer’s disease prediction and sex-specific biological insights [https://www.nature.com/articles/s43587-024-00573-8],” online through the journal Nature.. Learn more about Sirota Lab on their website [https://sirotalab.ucsf.edu/]. Learn more about Dr. Sirota on her UCSF profile [https://profiles.ucsf.edu/marina.sirota]. Connect with us Find transcripts and more at our website [https://www.adrc.wisc.edu/dementia-matters]. Email Dementia Matters [dementiamatters@medicine.wisc.edu]: dementiamatters@medicine.wisc.edu Follow us on Facebook [https://www.facebook.com/wisconsinadrc] and Twitter [https://twitter.com/WisconsinADRC]. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter [https://www.adrc.wisc.edu/newsletter]. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s [https://supportuw.org/giveto/dementiamatters]. All donations go toward outreach and production.
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