Diabetes Nerd

He’s Off Mealtime Insulin: Here’s His Tzield Story

46 min · 2. juli 2026
episode He’s Off Mealtime Insulin: Here’s His Tzield Story cover

Beskrivelse

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] What if a newly diagnosed person with type 1 diabetes (T1D) could dramatically reduce their insulin needs, or even stop taking mealtime insulin altogether? In this episode of the Diabetes Nerd Podcast, we sit down with Jacob, who was diagnosed with T1D in February 2026 and enrolled in the Beta Preserve clinical trial just weeks later. The study is exploring whether two rounds of Tzield (teplizumab) can preserve insulin-producing beta cells more effectively than a single treatment. Just months after beginning treatment, Jacob has cut his basal insulin by more than half and no longer needs mealtime insulin. He shares what it was like to undergo 12 consecutive days of Tzield infusions, the side effects he experienced, and how his blood sugars and daily life have changed. We also discuss how Tzield works, why early screening for type 1 diabetes is becoming increasingly important, and what this research could mean for the future of T1D treatment. Most importantly, Jacob explains why he hopes his story inspires others to consider screening, clinical trials, and opportunities to preserve beta cell function after diagnosis. If you live with type 1 diabetes, care for someone who does, or want to stay informed about the latest diabetes research, this is an episode you won't want to miss. Would you consider participating in a clinical trial like this? Have questions about Tzield or T1D screening? Leave a comment. We'd love to hear your thoughts. Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com/ginger. [https://www.eversensecgm.com/ginger] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate] SUPPORT INDEPENDENT DIABETES EDUCATION 👉 If you found value in today's episode and want to support independent diabetes education, advocacy, and storytelling, you can leave a tip at buymeacoffee.com/diabetesnerd [https://www.buymeacoffee.com/diabetesnerd].  Every contribution helps keep the podcast going and allows us to continue bringing important conversations to the diabetes community.  Thank you for being here. 🧡 DISCLOSURE: Ginger is an affiliate of Glow Gummies and Good Journey Donuts. By using her links to purchase, she may receive a small commission at no extra cost to you. Enjoy!

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episode He’s Off Mealtime Insulin: Here’s His Tzield Story cover

He’s Off Mealtime Insulin: Here’s His Tzield Story

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] What if a newly diagnosed person with type 1 diabetes (T1D) could dramatically reduce their insulin needs, or even stop taking mealtime insulin altogether? In this episode of the Diabetes Nerd Podcast, we sit down with Jacob, who was diagnosed with T1D in February 2026 and enrolled in the Beta Preserve clinical trial just weeks later. The study is exploring whether two rounds of Tzield (teplizumab) can preserve insulin-producing beta cells more effectively than a single treatment. Just months after beginning treatment, Jacob has cut his basal insulin by more than half and no longer needs mealtime insulin. He shares what it was like to undergo 12 consecutive days of Tzield infusions, the side effects he experienced, and how his blood sugars and daily life have changed. We also discuss how Tzield works, why early screening for type 1 diabetes is becoming increasingly important, and what this research could mean for the future of T1D treatment. Most importantly, Jacob explains why he hopes his story inspires others to consider screening, clinical trials, and opportunities to preserve beta cell function after diagnosis. If you live with type 1 diabetes, care for someone who does, or want to stay informed about the latest diabetes research, this is an episode you won't want to miss. Would you consider participating in a clinical trial like this? Have questions about Tzield or T1D screening? Leave a comment. We'd love to hear your thoughts. Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com/ginger. [https://www.eversensecgm.com/ginger] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate] SUPPORT INDEPENDENT DIABETES EDUCATION 👉 If you found value in today's episode and want to support independent diabetes education, advocacy, and storytelling, you can leave a tip at buymeacoffee.com/diabetesnerd [https://www.buymeacoffee.com/diabetesnerd].  Every contribution helps keep the podcast going and allows us to continue bringing important conversations to the diabetes community.  Thank you for being here. 🧡 DISCLOSURE: Ginger is an affiliate of Glow Gummies and Good Journey Donuts. By using her links to purchase, she may receive a small commission at no extra cost to you. Enjoy!

2. juli 202646 min
episode The Real Story Behind Automated Insulin Pumps: Patients Built It First cover

The Real Story Behind Automated Insulin Pumps: Patients Built It First

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] What if diabetes technology could do most of the work for you? In this episode, Chris Wilson shares how the DIY diabetes community has spent years pushing insulin-delivery technology beyond its limits, helping to shape the future of automated diabetes management. From early CGM hacks to advanced algorithms that can learn insulin needs with minimal input, Chris explains how grassroots innovation continues to influence the tools people with type 1 diabetes use today. We discuss: • The origins of the "We Are Not Waiting" movement • How DIY systems evolved into today's advanced algorithms • The role of open-source communities in accelerating innovation • The risks and rewards of testing new technology • What the future could hold for pumps, CGMs, and automated insulin delivery Whether you're curious about DIY looping, diabetes technology, or where diabetes care is headed next, this conversation offers a fascinating look at the people driving progress. Guest Chris Wilson is a programmer, advocate, and longtime contributor to the DIY diabetes community who has helped develop and test some of the most innovative insulin delivery systems available today. Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com. [https://www.eversensecgm.com/] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate] SUPPORT INDEPENDENT DIABETES EDUCATION 👉 If you found value in today's episode and want to support independent diabetes education, advocacy, and storytelling, you can leave a tip at buymeacoffee.com/diabetesnerd [https://www.buymeacoffee.com/diabetesnerd].  Every contribution helps keep the podcast going and allows us to continue bringing important conversations to the diabetes community.  Thank you for being here. 🧡 DISCLOSURE: Ginger is an affiliate of Glow Gummies and Good Journey Donuts. By using her links to purchase, she may receive a small commission at no extra cost to you. Enjoy!

25. juni 20261 h 11 min
episode Eledon's Type 1 Diabetes Cure: What's Fact and What's Fiction? cover

Eledon's Type 1 Diabetes Cure: What's Fact and What's Fiction?

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] We can be excited and practical at the same time. It's important to look beyond the headlines at the specific challenges within any clinical trial aiming to cure type 1 diabetes.  Recently, I've been accused of "smearing" the Eledon study because I've explained that—even though the results are extraordinary—this therapy is still a long way from becoming a cure that's available to thousands, let alone millions, of people living with type 1 diabetes. So today, I sat down with someone who knows this therapy better than almost anyone: * Katie Beth Hand (Find her on Instagram: https://www.instagram.com/calamitykatiebeth/ [https://www.instagram.com/calamitykatiebeth/]) Katie Beth is one of the participants in the University of Chicago study using Eledon's anti-rejection drug, tegoprubart, alongside transplanted islet cells. She's currently living insulin-free because of that treatment. In this conversation, we talk about what life is actually like after transplant, what the therapy involves, the benefits, the limitations, the business behind a clinical trial, and why it's important to be both excited and realistic about where this research stands today. You don't have to choose between hope and honesty. We can have both. Watch the interview and decide for yourself.  Other interviews I've done with Eledon study participants:  * Katie Beth - 1 month post-transplant [https://youtu.be/ZflOjMW-4MI]  * Katie Beth - 3 months post-transplant [https://youtu.be/X-_ybqfeo_Q]  * Chris Pacheco - 4 months post-transplant [https://youtu.be/XmGF-FrHtbI]  * The Problem with Eledon's Cure for T1D [https://youtu.be/kvwqRyYRjEw] Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com. [https://www.eversensecgm.com/] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate] SUPPORT INDEPENDENT DIABETES EDUCATION 👉 If you found value in today's episode and want to support independent diabetes education, advocacy, and storytelling, you can leave a tip at buymeacoffee.com/diabetesnerd [https://www.buymeacoffee.com/diabetesnerd/].  Every contribution helps keep the podcast going and allows us to continue bringing important conversations to the diabetes community.  Thank you for being here. 🧡 DISCLOSURE: Ginger is an affiliate of Glow Gummies and Good Journey Donuts. By using her links to purchase, she may receive a small commission at no extra cost to you. Enjoy!

22. juni 20261 h 13 min
episode The Truth About Insulin Pump Transitions (Don't Make These Mistakes) cover

The Truth About Insulin Pump Transitions (Don't Make These Mistakes)

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] Most people with diabetes (PWD) struggle with insulin pump transitions, but expert Maressa Spohn reveals if you're doing it right, and how to avoid the common pitfalls that could cost you control and peace of mind. If you’re considering an insulin pump or have recently switched, this episode is your essential guide to mastering the move and thriving with technology. Diagnosed at age three, Marissa Spohn has lived with type 1 diabetes (T1D) for over 35 years. She knows what works and what doesn’t when it comes to pumps and automated insulin delivery (AID). She shares practical tips on transitioning from multiple daily injections (MDI) to a pump, including how to trust the system, fine-tune settings, and prevent those frustrating highs and lows that often trip people up months after starting. In this episode of the Diabetes Nerd Podcast, you'll discover: 1. Why many patients struggle with proactive pump management, and how to set yourself up for success from day one. 2. Common mistakes like overriding algorithms and how to develop confidence in your system. 3. How to handle prolonged highs, site issues, and sensor inaccuracies without panic. 4. The nuance of using adjunct tools like Afrezra and GLP-1s to improve control. 5. Key strategies for exercising, stress, and hormonal changes that influence insulin needs. We break down the misconceptions around pump automation, emphasizing that even the smartest algorithms require your active involvement. Marissa shares her insights on adjusting basal rates during menstruation! Thanks for tuning in! Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM sensor. See if it's right for you at eversensecgm.com [https://www.eversensecgm.com/]. Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com. [https://www.eversensecgm.com/] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate] SUPPORT INDEPENDENT DIABETES EDUCATION 👉 If you found value in today's episode and want to support independent diabetes education, advocacy, and storytelling, you can leave a tip at buymeacoffee.com/diabetesnerd [https://www.buymeacoffee.com/diabetesnerd/].  Every contribution helps keep the podcast going and allows us to continue bringing important conversations to the diabetes community.  Thank you for being here. 🧡 DISCLOSURE: Ginger is an affiliate of Glow Gummies and Good Journey Donuts. By using her links to purchase, she may receive a small commission at no extra cost to you. Enjoy!

18. juni 202657 min
episode Parenting a T1D Teen Without Becoming the ‘Blood Sugar Police’ cover

Parenting a T1D Teen Without Becoming the ‘Blood Sugar Police’

Send us Fan Mail [https://www.buzzsprout.com/2465728/fan_mail/new] Managing type 1 diabetes (T1D) during the teen years can feel like a constant balancing act. In this episode, Yale pediatric endocrinologist and person living with T1D, Dr. Laura Nally, shares practical strategies to help parents support their teens with more confidence and less conflict. Learn why blood sugar responses to exercise aren't one-size-fits-all, how nutrition and physical activity work together, and what parents can do to help teens build independence while staying safe. Dr. Nally discusses her research on exercise and diabetes, including how identifying individual patterns can lead to smarter management decisions. We also explore common challenges such as preventing lows during sports, using protein to support blood sugar stability, and avoiding the "blood sugar police" approach that can damage trust and communication. Plus, hear how diabetes technology can reduce mental burden while still encouraging teens to develop essential self-management skills. Whether you're a parent, healthcare professional, or someone supporting a teen with type 1 diabetes, this episode offers practical insights to help young people thrive—both physically and emotionally. Thanks for tuning in! Join the Diabetes Nerd Network. [https://www.diabetesnerdnetwork.com/] Thanks to Eversense for sponsoring the Diabetes Nerd Podcast. Eversense is home to the world's only 365-Day CGM. See if it's right for you at eversensecgm.com. [https://www.eversensecgm.com/] DISCLAIMER: This video is not medical advice. Ginger Vieira is not a doctor. Please consult your healthcare team before making any changes to your healthcare regimen. FIND MORE FROM GINGER VIEIRA * YOUTUBE [https://www.youtube.com/@diabetesnerd] * BOOKS [https://www.amazon.com/stores/author/B008ZPEGQ6/allbooks] * ARTICLES [https://www.gingervieira.com/diabetes]  * INSTAGRAM [https://www.instagram.com/GingerVieira.T1D]  * LINKEDIN [https://www.linkedin.com/in/GingerVieira]  GINGER's DIABETES BOOKS * 🔥 NEW RELEASE: Every Day with Diabetes [https://www.amazon.com/Every-Day-Diabetes-Tips-Real/dp/B0H2SCRNM4/] * Stop Overeating During Lows [https://a.co/d/g4iRcxJ] * Exercise with Diabetes [https://amzn.to/3RQd1NK] * Dealing with Diabetes Burnout [https://amzn.to/3th5QF7] * Pregnancy with Type 1 Diabetes [https://amzn.to/3GOC4dO] * Emotional Eating with Diabetes [https://amzn.to/48nkRE0] * When I Go Low [https://amzn.to/48kCxju] * Ain't Gonna Hide my T1D [https://amzn.to/3GOlASW] GINGER’S FAVE DIABETES-FRIENDLY PRODUCTS * Treat Lows Fast with Glow Gummies [https://glowgummies.com/?aff=9]  * Enjoy Donuts Guilt-free with Good Journey [https://goodjourneydonuts.com/?sca_ref=10738228.9NBRGXD6P8&utm_source=affiliate&utm_medium=social&utm_campaign=affiliate]

11. juni 202644 min