Why Most Clinical Trials Fail | Dr. David & Jeremiah Bearss

Why Most Clinical Trials Fail | Dr. David & Jeremiah Bearss

Every year, promising therapies fail in clinical trials. But failure doesn't always mean the drug didn't work. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explain how clinical trials work, why so many therapies never make it to patients, and the complexity behind bringing a new medicine to market. They discuss the different reasons a clinical trial may fail, why meeting a clinical endpoint doesn't always lead to FDA approval, and how commercial viability plays a major role in determining whether a therapy ultimately reaches patients. The conversation also explores how artificial intelligence may transform drug development by identifying biological patterns and therapeutic targets that humans would struggle to find on their own. Topics covered include: • Why drugs fail clinical trials• The challenges of FDA approval and commercialization• How AI could improve the future of drug development 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

Anti-Aging vs Healthspan| Dr. Jeremiah & David Bearss

The anti-aging industry promises longer life, but is that really the goal? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss separate science from hype as they discuss what actually matters when it comes to aging. They explore why many age-related diseases are closely tied to the biology that helps us reproduce, why curing a single disease like cancer would add surprisingly little to the average human lifespan, and why the real goal should be extending healthspan rather than simply living longer. The conversation also looks at why so much healthcare spending occurs in the final years of life and what individuals can do today to stay healthier for longer. Topics covered include: • Why aging and cancer are biologically connected• The difference between lifespan and healthspan• Why staying healthy matters more than simply living longer 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

Gene Editing Could Change Medicine Forever| Dr. Jeremiah & David Bearss

Gene editing has long felt like science fiction. Today, it is becoming a clinical reality. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explore the rapid progress of gene editing and the opportunities and ethical questions that come with it. They discuss new evidence suggesting that a single treatment may be able to permanently edit genes in the liver to lower cholesterol, the ethical challenges surrounding gene editing in embryos, and why preventing disease before it begins may fundamentally change the future of medicine. The conversation examines not only what gene editing can do, but also how society should think about using it responsibly. Topics covered include: • How gene editing is moving from theory to reality• The ethical questions surrounding embryo gene editing• Preventing disease before it ever develops 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

Can AI Be Trusted to Discover New Medicine? | Dr. Jeremiah & David Bearss

Artificial intelligence is transforming medicine, but there is one major challenge that doesn't get enough attention. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss how AI models are trained, why scientific literature isn't always perfect, and what that means for the future of drug discovery. They explore how inaccurate or noisy data can influence AI systems, why reproducibility has become a major issue in scientific research, and the importance of building better datasets before relying on AI to develop the next generation of medicines. The conversation also highlights why improving the quality of science may be just as important as improving the quality of AI. Topics covered include: • Why AI is only as good as the data it learns from• The challenge of noise and reproducibility in science• Building better AI for the future of medicine 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

The Accidental Origins of Modern Medicine | Nathan Chow

Many of the medicines we rely on today came from unexpected places. In this episode of the Good Medicine Podcast, Dr. Jeremiah Bearss sits down with Nathan Chow to explore the origins of modern pharmacology and the surprising discoveries that shaped medicine as we know it. They discuss how the synthetic dye industry played a major role in the development of modern drug discovery, why curiosity has always been one of the most important drivers of scientific progress, and how today's AI tools are helping researchers identify patterns and opportunities that humans may miss. The conversation also explores the human side of medicine and why remembering where drugs come from helps keep the field grounded in the curiosity and creativity that built it. Topics covered include: • The connection between the dye industry and modern pharmacology• How curiosity drives scientific discovery• Why AI may transform the future of drug development 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]