The Longevity Medicine Paradox - Adam Carewe, MD (General Medicine)

The Future of AI in Healthcare with Hugh Barrigan, Chris Page, and Askash Saraiya

In this eye-opening episode, I sit down with Hugh Barragan, a technologist and CTO based out of Boston, Dr. Chris Page, an anesthesiologist and pain medicine physician, and Dr. Akash Soraya, an emergency medicine physician and angel investor, to tackle one of the most pressing questions in medicine today: has technology made healthcare better or worse? We dive deep into the promise and peril of AI, examining whether electronic medical records have been a net positive despite their frustrations, and what the future holds when AI can diagnose faster and more accurately than any physician. The conversation gets real as we discuss whether AI will replace doctors, who takes accountability when algorithms make mistakes, and whether patients will even care if they are talking to a human or a machine. Key Highlights 🏥 Technology's Mixed Impact: While EMRs have made information more accessible and eliminated handwriting issues, they have also created overwhelming data overload and shifted optimization toward billing rather than patient care. 💰 The Cost Paradox: Healthcare costs have skyrocketed since the introduction of EMRs, yet life expectancy has remained flat at roughly 80 years for 15 years - suggesting technology has not fundamentally improved population health outcomes. 🤖 AI Will Replace Physicians: Dr. Akash boldly predicts that AI will eventually outperform emergency physicians at diagnosis and hopes it happens soon, while acknowledging the massive workforce displacement this would cause across 15-20% of the U.S. economy. ⚖️ The Accountability Problem: Hugh emphasizes that computers cannot be held accountable for decisions, creating a fundamental challenge as AI becomes capable of autonomous clinical decision-making - someone must remain responsible when things go wrong. 🩺 Trust and Human Connection: Dr. Chris argues that patients will continue wanting human care for a long time, as the rapport and comfort provided by a real physician cannot easily be replicated - though AI may eventually convince people otherwise. 📊 The Revenue Cycle Machine: Only 20% of healthcare costs are actual human labor - the rest is driven by increasingly sophisticated billing optimization, which AI will likely accelerate rather than reduce, making healthcare even more expensive. 🛡️ Malpractice Insurance for AI: The panel predicts that by 2028-2029, insurance companies will begin underwriting malpractice coverage for fully autonomous AI clinicians, though the actuarial curves and liability frameworks remain completely undefined. 🥊 The Coming AI War: Hugh predicts a shadow AI war in healthcare where patient AIs fight billing AIs, insurer AIs battle provider AIs, and costs spiral as a

The Truth About Entrepreneurship Nobody Talks About - Preston Alexander

The Truth About Entrepreneurship Nobody Talks About In this episode, Dr. Rishad Usmani sits down with Preston Alexander, co-founder of Forward Slash Health, a consultancy helping clinicians reclaim autonomy in medicine. From building furniture and rock climbing in Colorado to launching a medical device startup during the pandemic, Preston’s unconventional path shows how curiosity, grit, and timing can shape a career in healthcare entrepreneurship. He opens up about his early days as a psychology and philosophy student, his accidental entrance into healthcare, and how witnessing the corporatization of medicine inspired his mission to empower doctors to lead the business side of care. Preston and Dr. Usmani discuss the broken incentives driving U.S. healthcare, why AI might make us forget how to think, and how to balance friction and optionality when building impactful products. With candor and humor, Preston explores the lessons behind his successes and failures — from cold-calling hospitals during COVID to building a startup that helps physicians regain ownership of their work and their purpose. Key Highlights: 💡 From Climbing Walls to Boardrooms: How Preston went from rock climbing and furniture making to leading healthcare startups. 📘 Learning by Doing: Why he faked being an “MBA candidate,” accidentally earned the degree, and discovered his love for business strategy. 🏥 Inside the Medical Machine: How working in medical devices revealed the tension between innovation, regulation, and corporate growth. 🚀 Starting Up in a Pandemic: The story of launching a surgical device company in February 2020 — and cold-calling hospitals through lockdowns. 🧠 Taking Back Healthcare: How Forward Slash Health helps physicians rebuild independence and rethink the business of medicine. 🤖 AI and the Death of Thinking: Why Preston is both fascinated and frustrated by artificial intelligence and fears it may make humanity less thoughtful. 🎓 Education and Creativity: Why he believes traditional schooling traps curiosity and how parents can rethink education for the next generation. ⚙️ Friction vs. Optionality: The philosophy behind designing products, systems, and companies that are both user-friendly and purpose-driven. Resources & Next Steps: 🌐 Visit https://forwardslashhealth.comforwardslashhealth.com [http://forwardslashhealth.com] to learn more about their mission. 📲 Connect with Preston Alexander on LinkedIn. [https://www.linkedin.com/in/preston-alexander/]🎧 Explore more episodes of Learning with Rishad [https://podcasts.apple.com/nz/podcast/learning-with-rishad/id1655592441] for deep conversations at the intersection of medicine, AI, and human behavior.

The Longevity Medicine Paradox - Adam Carewe, MD (General Medicine)

Inside the Mind of the “Guinea Pig Generation” and the Future of AI in Healthcare In this episode, Dr. Rishad sits down with Dr. Adam Carewe, a physician-turned-healthtech innovator who believes we are the “guinea pig generation” in modern medicine. From his beginnings as a college basketball player and math enthusiast to becoming Chief Medical Information Officer at Kaiser Permanente, Adam shares his journey into the world of healthcare technology and startups. Together, they explore the intersection of medicine, technology, and uncertainty — discussing the limits of what doctors know, the rise of AI-assisted diagnostics, and the ethical challenges of over-testing in modern healthcare. Adam also reflects on his leap from a secure medical leadership position into the startup world, and why he believes the future of medicine lies in automating the routine to preserve the human. With humility and candor, Adam opens up about mental vs. physical health, longevity hype, and what he’d tell his younger self about taking risks and following instinct. Key Highlights: 🧬 The Guinea Pig Generation: Why today’s patients and physicians live in an era where data grows faster than understanding. 📊 From Equations to Empathy: How Adam’s background in math and exercise science shaped his systems-thinking approach to patient care. 🤖 The AI Physician Debate: When AI might safely assist or even replace parts of clinical decision-making. 🧠 Mind and Body as One: Why the separation between mental and physical health is outdated and counterproductive. ⚕️ Too Many Tests, Too Little Meaning: How modern diagnostics often outpace interpretation, creating anxiety and unnecessary procedures. 🚀 Taking the Leap: Why Adam left a high-level role at Kaiser Permanente to join a startup, and what he’d tell his younger self about courage and timing. Resources & Next Steps: 📲 Follow Dr. Adam Carewe on LinkedIn [https://www.linkedin.com/in/adam-carewe] for insights on clinical innovation and healthcare tech. 🎧 Explore more episodes of Learning with Rishad [https://podcasts.apple.com/nz/podcast/learning-with-rishad/id1655592441] for deep conversations at the intersection of medicine, AI, and human behavior. 🧠 Read about AI in clinical decision-making in publications like NEJM Catalyst or PubMed. 💡 Learn more about General Medicine, the startup Adam joined after leaving Kaiser Permanente. Episode Breakdown: 00:00 We Are the Guinea Pig Generation 00:51 Adam’s Early Journey 05:20 When Tech Meets Medicine 08:41 Will AI Replace Doctors? 10:46 ChatGPT & Health Data 15:05 Mind vs. Body 19:17 The Longevity Paradox 24:15 Too Much Testing, Too Little Clarity 29:19 Whole-Body MRI & Overdiagnosis 34:33 Tracking Everything 38:05 Fixing the System 40:36 Final Reflection

A surgeon's path to fixing healthcare - Ben Schwartz (Commons Clinic)

In this episode, I sat down with Ben, an orthopedic surgeon who is making a significant career change after 17 years. He's moving away from his clinical practice to a leadership role at Commons Clinic, a company focused on value-based care. In our conversation, we explored his motivations for this major pivot, the frustrations of the traditional healthcare system, and his vision for a future that seamlessly blends technology with human-centric care. Ben opened up about the "death by a thousand cuts" that he believes leads to physician burnout, highlighting issues like the tedious nature of EMRs and the complexities of regulations. He explained how his personal journey into entrepreneurship gave him a renewed sense of purpose, shifting his focus from treating one patient at a time to impacting healthcare on a broader scale. Our discussion also delved into the roles of AI and robotics in orthopedics, the challenges of implementing value-based care without "cherry-picking" patients, and the critical importance of shared decision-making in the patient-physician relationship. This episode is for anyone curious about the future of healthcare, the reality of physician burnout, and the exciting intersection of technology and medicine. Timestamps 00:07:48 - Ben's personal journey from being a surgeon to a leader in healthcare innovation. 00:11:27 - Ben shares what he'll miss most about being a surgeon and what he's happy to leave behind. 00:13:53 - We discuss if the entrepreneurial spirit is something you're born with or if it can be learned. 00:15:41 - Ben's thoughts on the future of arthritis treatments, beyond what's currently available. 00:18:50 - We talk about why so many doctors are burning out and how Ben managed to avoid it. 00:27:50 - The growing disconnect between doctors on the front lines and hospital administration. 00:30:00 - Ben reveals a major belief he's changed his mind on over the last few years. 00:41:18 - We explore the role of robotics and AI in the field of orthopedic surgery. 00:46:35 - Ben gives his take on a hot topic: Will AI replace doctors? 00:58:02 - We get into the complicated issue of patient liability in a "consumerized" healthcare system.

Beyond the Turing Test: The Artificial Consciousness Challenge - Prof. Ronjon Nag (Stanford)

Join Rishad Usmani in a profound conversation with engineer and investor Ronjon Nag as they explore the very fabric of our existence in an age of rapidly advancing AI. This episode ventures far beyond typical tech talk, diving deep into philosophical questions about what constitutes reality, the elusive nature of consciousness (both human and artificial), the future of work in an era of abundance, and the persistent human drive for tribalism. Ronjon Nag, with his pragmatic engineering perspective, offers fascinating insights into how AI is not just changing technology, but reshaping our understanding of ourselves and the world around us. From the potential for an "aging vaccine" to the unsettling implications of a world where digital truth is easily manipulated, this episode will challenge your perceptions and spark new ways of thinking about humanity's trajectory. In this episode, you will learn: * How engineers define reality: Beyond subjective perception, exploring the physical world and mental projections. * The elusive nature of consciousness: A deep dive into different theories, from autonomous processes to quantum forces, and whether AI can ever truly achieve it. * The "Artificial Consciousness Test": What it would take for a machine to truly feel and understand human concepts. * The future of work in an AI-powered world: Will AI usher in an era of abundance where humans no longer need to work? The "lump of labor" theory vs. insatiable human desires. * Human tribalism in a globalized world: Why do we cling to groups, and how might companies become the new "tribes" in a shifting power dynamic? * The changing nature of truth: How AI's ability to create deepfakes and fake information threatens digital reality and elevates the importance of trusted curators and physical interaction. * Moonshot thinking in longevity science: Ronjon's groundbreaking work on an mRNA "aging vaccine" and pan-cancer solutions. Guest Bio: Ronjon Nag is an accomplished engineer, inventor, and investor, with a deep expertise in AI, longevity sciences, and venture capital. His pragmatic approach to complex problems offers a unique lens through which to view the future of technology and its impact on humanity.