Lyt til Neurology® Podcast

The May 2025 recall features four previously posted episodes on myasthenia gravis. The first episode has Dr. Fredrik Piehl discussing rituximab for new-onset generalized MG. In the second episode, Dr. Vera Bril explores the potential use of immunoglobulin as a corticosteroid-sparing agent in MG patients. The third episode features Dr. Ali A. Habib discussing trends in hospital admissions and in-hospital mortality for adult MG patients. The series concludes with Dr. Jennifer Morganroth addressing the increase in thymectomy procedures post-MGTX trial, disparities in access to these surgeries among different demographic groups, and the rise of minimally invasive surgical techniques. Podcast links: Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis [https://directory.libsyn.com/episode/index/id/25227471]  Corticosteroid-Sparing Effects of Immunoglobulin in Myasthenia Gravis [https://directory.libsyn.com/episode/index/id/26141046] Hospitalizations and Mortality from MG Hospitalizations and Mortality From Myasthenia Gravis [https://directory.libsyn.com/episode/index/id/29389973] Trends and Disparities in the Utilization of Thymectomy for MG in the US [https://directory.libsyn.com/episode/index/id/35950280] Article links: Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis [https://jamanetwork.com/journals/jamaneurology/fullarticle/2796552] Randomized Double-Blind Placebo-Controlled Trial of the Corticosteroid-Sparing Effects of Immunoglobulin in Myasthenia Gravis [https://www.neurology.org/doi/10.1212/wnl.0000000000201501] Hospitalizations and Mortality From Myasthenia Gravis [https://www.neurology.org/doi/10.1212/WNL.0000000000207863] Trends and Disparities in the Utilization of Thymectomy for Myasthenia Gravis in the United States [https://www.neurology.org/doi/10.1212/CPJ.0000000000200335] Disclosures can be found at Neurology.org [Neurology.org].

Dr. Greg Cooper talks with Dr. Joseph Therriault about the use of plasma biomarkers in diagnosing Alzheimer disease, emphasizing the importance of interpreting these biomarkers within the clinical context of the patient.  Read the related article in Nature [https://doi.org/10.1038/s43587-024-00731-y]. Disclosures can be found at Neurology.org [Neurology.org].

Dr. Halley Alexander talks with Dr. Paula Marques about sex differences in genetically determined epilepsies. Read the related article in Neurology® Genetics [https://www.neurology.org/doi/10.1212/NXG.0000000000200233]. Disclosures can be found at Neurology.org [Neurology.org].

Dr. Tesha Monteith talks with Dr. Peter Goadsby about advances in headache science and classification.  Read the editorial about ICHD-4 [https://journals.sagepub.com/doi/10.1177/03331024251325550]. Disclosures can be found at Neurology.org [Neurology.org].

Dr. Justin Abbatemarco talks with Dr. Jiwon Oh about Bruton Tyrosine Kinase (BTK) Inhibitors and the recent data on tolebrutinib in multiple sclerosis. Read the related article on Tolebrutinib versus Teriflunomide in The New England Journal of Medicine [https://www.nejm.org/doi/full/10.1056/NEJMoa2415985]. Read the related article on Tolebrutinib in Nonrelapsing Secondary Progressive MS in The New England Journal of Medicine [https://www.nejm.org/doi/full/10.1056/NEJMoa2415988]. Disclosures can be found at Neurology.org [Neurology.org].