The PQI Podcast
Season 10, Episode 10: Clearing the Fog: A Clinical Look at Chemo Brain with Jorg Dietrich, MD, PhD Cognitive changes during cancer treatment, often called “chemo brain,” can significantly impact a patient’s quality of life. In this episode, Jorg Dietrich, MD, PhD, Clinical Director of the Cancer & Neurotoxicity Clinic at Massachusetts General Hospital and Associate Professor of Neurology at Harvard Medical School, shares his expertise on the neurologic effects of cancer therapies. Dr. Dietrich discusses the biology behind treatment-related cognitive changes, including the impact of chemotherapy, radiation, and immunotherapy on the brain’s cellular environment. He provides insight into how these symptoms present in clinical practice and how they can vary across patients. The conversation also focuses on practical strategies for the multidisciplinary oncology team. From early recognition and patient education to supportive care approaches, this episode highlights how pharmacists, providers, and the broader care team can work together to address cognitive side effects and improve patient outcomes. Dr. Dietrich brings a unique perspective through his leadership in cancer neuroscience and brain repair research, with over 200 publications advancing the understanding of neurotoxicity and recovery in cancer care. This episode offers valuable insight for oncology professionals looking to better support patients experiencing cognitive changes throughout their treatment journey.
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