Cover image of show Less of You: Life on Semaglutide & Tirzepatide

Less of You: Life on Semaglutide & Tirzepatide

Podcast by Eva Sheie & Kami Gamlem

English

Personal stories & conversations

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About Less of You: Life on Semaglutide & Tirzepatide

Eva + Kami are two old-ish moms confronting our reasons for being obese while losing weight on semaglutide and tirzepatide, and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast. After a friend (who is a plastic surgeon) talked Eva into starting semaglutide in February of 2023, she lost 70 pounds in 14 months, alternating between long stretches of being stalled at the same weight and consistent but slow weight loss.  Chasing a lifelong dream to being considered just overweight and not obese by the BMI calculator, after 14 months Eva switched to tirzepatide to try and reach a goal that still seems just out of reach. A prolific eater of her feelings, Kami was tired of being uncomfortable and when she heard through a mutual friend how semaglutide had changed Eva’s life, she found a trusted medical weight loss provider and took the first step. As Kami starts her life on semaglutide, Eva adjusts to a world with less food noise and figures out how to let go of the crippling negative self-talk. On each episode, we connect on how our lives are changing in real time as semaglutide and tirzepatide help us be smaller people, and try to answer the bigger question for ourselves: When there’s less of you, what is left?

All episodes

41 episodes

episode Why you shouldn’t go off meds artwork

Why you shouldn’t go off meds

Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com [http://lessofyou.com] To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. [https://www.theaxis.io/]  Follow us on Instagram @lessofyoupodcast  [https://www.instagram.com/lessofyoupodcast/] Co-hosts: Eva Sheie & Kami Gamlem Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Victoria Cheng Theme music: Old Grump, Smartface Less of You is a production of The Axis [https://www.theaxis.io/]

27 Mar 2026 - 31 min
episode The Dryer Shrunk My Jeans artwork

The Dryer Shrunk My Jeans

Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size comments at work. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com [http://lessofyou.com] To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. [https://www.theaxis.io/]  Follow us on Instagram @lessofyoupodcast  [https://www.instagram.com/lessofyoupodcast/] Co-hosts: Eva Sheie & Kami Gamlem Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Victoria Cheng Theme music: Old Grump, Smartface Less of You is a production of The Axis [https://www.theaxis.io/]

9 Jan 2026 - 29 min
episode I took a 4 week break from semaglutide and here’s what happened artwork

I took a 4 week break from semaglutide and here’s what happened

Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years. Check out Murderland: Crime and Bloodlust in the Time of Serial Killers [https://a.co/d/aOqG8Jd] Shop Shapermint [https://shapermint.com/] Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com [http://lessofyou.com] To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. [https://www.theaxis.io/]  Follow us on Instagram @lessofyoupodcast  [https://www.instagram.com/lessofyoupodcast/] Co-hosts: Eva Sheie & Kami Gamlem Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Victoria Cheng Theme music: Old Grump, Smartface Less of You is a production of The Axis [https://www.theaxis.io/]  This episode includes AI-generated content.

14 Nov 2025 - 37 min
episode You Want Fries With That? artwork

You Want Fries With That?

After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too. New compounded meds including glycine and B12 make a noticeable dent in Eva’s persistent body aches. A 3-week pause in medication to get a tooth pulled has a surprising effect.  We deconstruct our instincts to soften bad news by bribing our children with treats like McDonald’s. Listen to the new addiction & recovery podcast My Last Relapse [https://www.mylastrelapse.com/] Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com [http://lessofyou.com] To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. [https://www.theaxis.io/]  Follow us on Instagram @lessofyoupodcast  [https://www.instagram.com/lessofyoupodcast/] Co-hosts: Eva Sheie & Kami Gamlem Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Spencer Clarkson Theme music: Old Grump, Smartface Less of You is a production of The Axis [https://www.theaxis.io/]

3 Oct 2025 - 30 min
episode Replacing one addiction with another? artwork

Replacing one addiction with another?

While working on a project about addiction, Eva realizes she went from drinking and smoking to a food addiction. But she’s not even sure what her “thing” is now, which is… a little terrifying.  Meanwhile, Kami loses some weight—not exactly from a wellness plan, but courtesy of stress and no sleep. Hey, a win’s a win. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com [http://lessofyou.com] To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. [https://www.theaxis.io/]  Follow us on Instagram @lessofyoupodcast  [https://www.instagram.com/lessofyoupodcast/] Co-hosts: Eva Sheie & Kami Gamlem Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Spencer Clarkson Theme music: Old Grump, Smartface Less of You is a production of The Axis [https://www.theaxis.io/]

5 Sep 2025 - 17 min
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