Modern Metabolic Health with Dr. Lindsay Ogle, MD

Fatigue On GLP-1s: Why It's Happening And How To Fix It

27 min · 15. juni 2026
episode Fatigue On GLP-1s: Why It's Happening And How To Fix It cover

Description

We break down why fatigue can show up on GLP-1 medications and why the fix depends on the real cause, not a one-size-fits-all trick. We walk through four common drivers and the practical next steps that help you feel energized while still moving toward your weight loss and metabolic health goals.  • underfueling on GLP-1 due to strong appetite suppression and overly aggressive calorie restriction  • balancing calories with a slight deficit to support weight loss without draining daily energy  • macronutrient balance and why extreme low-carb approaches can leave some people exhausted  • when to consider discussing a lower GLP-1 dose with your doctor  • micronutrient basics and who needs extra attention due to absorption issues  • three key labs to ask about for fatigue: vitamin D, ferritin, and vitamin B12  • vitamin D targets, sunlight timing, food sources, and safe supplementation monitoring  • iron deficiency fatigue despite a normal CBC and why ferritin matters  • iron treatment options including food, every-other-day oral iron, and IV iron when needed  • sleep quantity and sleep quality as major fatigue drivers  • sleep hygiene fundamentals and CBT-I as first-line care for primary insomnia  • obstructive sleep apnea symptoms, home testing, and CPAP as the most effective treatment  • normal temporary fatigue during weight loss and when it signals a bigger problem  If you found this information helpful, please share with a friend, family member, or colleague. Please subscribe and write a review. ---------------------------------- How to improve your sleep (Dr. Ogle YouTube) [https://youtu.be/4cBwDHNIUjQ?si=62p_ts8mfl5pmm4p] CBT-i Free App (for insomnia) [https://apps.apple.com/us/app/cbt-i-coach/id655918660] 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

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75 episodes

episode Pediatric Obesity With Dr. Lisa Tritto, MD artwork

Pediatric Obesity With Dr. Lisa Tritto, MD

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episode Fertility, Weight, And Metabolic Health artwork

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episode Food Aversions on GLP-1 Medications artwork

Food Aversions on GLP-1 Medications

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episode Plant Based Nutrition With Dr. Shayla Toombs-Withers, DO artwork

Plant Based Nutrition With Dr. Shayla Toombs-Withers, DO

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9. juli 202627 min
episode The Original Weight Loss Meds: Phentermine, Qsymia, and Contrave artwork

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GLP-1 medications are everywhere right now, but the “older” obesity medications never stopped helping real patients and they can still be the right tool when matched well. I walk through the three FDA-approved first-generation obesity management options and how I think about using them safely in modern obesity medicine, especially when cost, access, or specific symptoms like cravings are part of the story. We start with phentermine, the original FDA-approved weight loss medication, and get practical about what it actually does: appetite suppression, typical stimulant-like side effects, morning dosing, expected weight loss, and the key reasons it may be unsafe (like uncontrolled high blood pressure, certain heart conditions, glaucoma, or uncontrolled hyperthyroidism). Then we move into Qsymia, the phentermine plus topiramate combination, including why it tends to produce more weight loss, what to know about pricing, and the topiramate-specific risks like teratogenicity, kidney stones, fatigue, taste changes, and tingling sensations. Next, we dig into Contrave (bupropion plus naltrexone) and why it can be a great fit when food cravings, emotional eating, mood symptoms, or goals like cutting back on alcohol or smoking are front and center. I also explain the non-negotiable safety rules: no history of seizures, and no opioids of any kind, including products like kratom or 7OH, due to the risk of precipitated withdrawal. We close by talking strategy, including combining these oral options with GLP-1 therapy, using them for maintenance, and an honorable mention of metformin for insulin resistance and metabolic health. Subscribe, share this with someone who needs clear guidance, and leave a review so more people can find the podcast and improve their metabolic health. ------------------------------------------------- Qsymia discount program [https://qsymia.com/patient/multiple-ways-to-save] Contrave discount program [https://contrave.com/save/] 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

6. juli 202614 min