The Chase Merrill Podcast

Your Microbiome Is Going Extinct, Generation By Generation - Kiran Krishnan - #68

1 h 22 min · 1. juni 2026
episode Your Microbiome Is Going Extinct, Generation By Generation - Kiran Krishnan - #68 cover

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What's actually happening inside your gut? Modern diets, over-sterilized environments, and decades of bad supplement advice have quietly dismantled the microbiome that runs almost every system in your body — from your immune system to your brain. So what does a genuinely healthy microbiome look like, and what does it actually take to rebuild one? Expect to learn why 80% of gut-brain communication travels from gut to brain rather than the other way, how 40 grams of daily fiber cuts all-cause mortality by 40% (and why that would be a trillion-dollar pill if you could patent it), why the "kill the bad bacteria first" strategy has always been wrong, what leaky gut and LPS actually are and why one paper named them the number one driver of mortality and morbidity worldwide, why 98% of probiotics on store shelves are dead before they reach your intestines, and how our microbiome diversity has collapsed from 800–900 species in our ancestors to an average of 120 today and much more… - Save hundreds on the best saunas on the market: HERE [https://www.heavenlyheatsaunas.com/MERRILL] (use code MERRILL) Save on an amazing cold plunge: HERE [https://nordicwave.pxf.io/WOG6E3] (use code MERRILL) - Thank You For Listening To The Chase Merrill Podcast - Get in touch in the comments below or head: HERE [https://www.instagram.com/chasecmerrill/] - Kiran's Instagram: HERE [https://www.instagram.com/kiranbiome/] - 0:00 The Other Brain: Why The Gut Runs Your Body 6:03 What Is "Gut Health"? Defining the Microbiome Spectrum 9:13 It's Daily Choices, Not Miracle Supplements 13:48 Reading The Signs: What Your Body Is Telling You 19:32 Your Gut Controls Your Immune System (Treg Cells and the Nobel Prize) 21:04 How To Build Gut Diversity With Food and Fiber 24:23 The Diet War: Why Picking A Camp Makes You Untrustworthy 32:44 Meal Hygiene: How You Eat Matters As Much As What You Eat 41:49 Why "Kill The Bad Bacteria" Is The Worst Gut Health Advice 47:35 Probiotics vs Prebiotics vs Postbiotics: What You Actually Need 54:29 Leaky Gut, LPS, and The #1 Driver of Chronic Disease 1:00:30 The Mass Extinction Of The Western Microbiome 1:08:24 High Protein, Rotten Farts, and Fasting: The Complete Picture 1:15:47 Closing Questions

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80 episodes

episode Your Brain Is A Crappy Office - David Allen - #80 artwork

Your Brain Is A Crappy Office - David Allen - #80

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Simone Stolzoff is a journalist, author, and TED speaker. What happens when the world gets more uncertain right as our tolerance for uncertainty keeps shrinking? Answers are a tap away, yet most people are more anxious and less equipped to sit with not knowing than ever before. So what's actually driving that gap, and how do you build the tolerance back? Expect to learn why our brains are biologically wired to treat uncertainty as a threat, the real story behind why Slack almost never existed, the difference between acute uncertainty and the ambient uncertainty we're all swimming in right now, why bracing for the worst might actually be a self-protective habit rather than a flaw, the two-by-two matrix for knowing where to actually spend your worry, why one-way door decisions and two-way door decisions require completely different thinking, how to build real trust in your future self's ability to handle whatever comes and much more… - Save hundreds on the best saunas on the market: HERE [https://www.heavenlyheatsaunas.com/MERRILL] (use code MERRILL) Save on an amazing cold plunge: HERE [https://tidd.ly/4fqqzf1] (use code MERRILL) - Thank You For Listening To The Chase Merrill Podcast - Get in touch in the comments below or head: HERE [ https://www.instagram.com/chasecmerrill/] - Simone's Instagram: HERE [https://www.instagram.com/thepizza_bagel/] Simone's Website: HERE [https://simonestolzoff.com/] - 0:00 Why Your Brain Treats Uncertainty As A Threat 3:37 The Founder Who Killed His Own Hit Game To Build Slack 7:36 Acute Vs. Ambient Uncertainty 8:54 The Two Faces Of Low Tolerance: Hoarding Info Or Winging It 10:09 Building Your Uncertainty Tolerance Like A Muscle 14:29 The Two-By-Two Matrix For Where To Spend Your Worry 15:19 Why Bracing For The Worst Might Be Self-Protective 18:58 The World Is Getting More Uncertain, Faster 20:50 The Job Offer That Wouldn't Let Simone Sleep 26:19 Diversifying Your Identity Beyond Your Job 32:02 Loneliness And The Shrinking Self 35:57 The Explore-Exploit Trade-Off 39:59 One-Way Doors Vs. Two-Way Doors 46:57 Closing Questions

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episode The World Is Quietly Running Out Of People - Dr Paul Morland - #78 artwork

The World Is Quietly Running Out Of People - Dr Paul Morland - #78

Dr. Paul Morland is a demographer, author, and researcher. What's actually happening to the global population? For decades we were warned about overpopulation, yet birth rates are now collapsing below replacement across most of the world, from China to Chile. So what happens to an economy, and a civilization, when there simply aren't enough people left to sustain it? Expect to learn why the overpopulation you were taught about is already reversing, how a fertility rate of 0.75 turns 100 grandparents into just 16 grandchildren, why China's population is set to halve by the end of the century, what the "silver tsunami" will do to taxes and pensions, why Paul doesn't blame microplastics or sperm counts for the birth crisis, whether AI and robots can actually replace a shrinking workforce, why no time will ever feel perfect to start a family and much more… - 0:00 From Overpopulation To Collapse 3:51 Why The Reversal Is Slow To Sink In 6:26 The Silver Tsunami Explained 9:47 Fertility Rate vs Replacement Rate 17:46 Where Fertility Rates Stand Now 22:07 How 100 Grandparents Become 16 23:38 Demographics, War And Power 28:18 Is Biology To Blame? 32:13 The Real Causes: Culture And Economics 38:39 Will AI And Robots Save Us? 44:21 Why Fewer People Won't Save The Planet 53:06 Japan, Britain And The US In 25 Years 1:00:44 Why No Time Is Ever Perfect 1:03:04 Closing Questions And Book Recs - Save hundreds on the best saunas on the market: HERE [https://www.heavenlyheatsaunas.com/MERRILL] (use code MERRILL) Save on an amazing cold plunge: HERE [https://tidd.ly/4fqqzf1] (use code MERRILL) - Thank You For Listening To The Chase Merrill Podcast - Get in touch in the comments below or head: HERE [https://www.instagram.com/chasecmerrill/] - Paul's Website: HERE [https://www.paulmorland.co.uk/]

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episode AI Is Not Coming For Your Job - Fawzi Ammache - #77 artwork

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Fawzi Ammache is an AI engineer, emerging-technology educator, and the creator of Future with Fawzi. What's actually going to happen with AI? Every headline swings between utopia and collapse, leaving most people anxious and convinced their job is next. So what's real, what's hype, and what should we actually be worried about? Expect to learn why the most useful AI will also be the most boring, whether AI is really coming for your job, why Fawzi doesn't believe AGI will ever arrive, what the data-center water debate gets wrong, why the biggest risk of AI is becoming more isolated, how to tell when to use AI and when to embrace friction, the difference between working AI-first and human-first and much more… - Save hundreds on the best saunas on the market: HERE [https://www.heavenlyheatsaunas.com/MERRILL ] (use code MERRILL) Save on an amazing cold plunge: HERE [https://tidd.ly/4fqqzf1] (use code MERRILL) - Thank You For Listening To The Chase Merrill Podcast - Get in touch in the comments below or head: HERE [Instagram: https://www.instagram.com/chasecmerrill/] - Fawzi's Instagram: HERE [https://www.instagram.com/futurewithfawzi/] Fawzi's Website: HERE [https://www.futurewithfawzi.com/] - 0:00 Why AI Doesn't Have To Be Scary 1:46 What's Behind The Magic Wand 3:16 The Three Real Fears About AI 4:13 Why Friction Is Good For You 5:08 Will AI Actually Take Your Job? 8:53 Why He Doesn't Buy AGI 12:48 AI Is The New Electricity 15:40 Self-Driving Cars And Vanishing Jobs 27:55 Are Data Centers Draining Our Water? 32:57 Treat AI Like A Normal Technology 35:39 The Real Danger Is Isolation 39:39 Quantum Computing Is Next 46:50 Let AI Do The Dishes, Not The Drawing 55:39 Three Things Everyone Should Do 1:00:04 Closing Questions

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episode Sexualized Social Media Is More Dangerous Than Porn - Dr. Trish Leigh - #76 artwork

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Dr. Trish Leigh is a neuroscientist, author, and neurofeedback specialist. What is pornography actually doing to your brain? It floods the reward system with levels of dopamine no real-world experience can match, and after only a couple of exposures — often in childhood — the brain recalibrates around the high. So why does it become so hard to stop, and what does it actually take to rewire the pattern? Expect to learn why porn qualifies as a supernormal stimulus your brain can't compete with, how dopamine desensitization quietly drives erectile dysfunction, why Dr. Leigh believes sexualized social media may be more dangerous than porn, what "strain brain" and "drain brain" reveal about screen compulsion, how neurofeedback can unwire and rewire an addicted brain, what every parent should do before handing a child a phone and much more… - Save hundreds on the best saunas on the market: HERE [https://www.heavenlyheatsaunas.com/MERRILL] (use code MERRILL) Save on an amazing cold plunge: HERE [https://tidd.ly/4fqqzf1] (use code MERRILL) - Thank You For Listening To The Chase Merrill Podcast - Get in touch in the comments below or head: HERE [https://www.instagram.com/chasecmerrill/] - Trish's Instagram: HERE [https://www.instagram.com/dr.trishleighofficial/] Trish's Website: HERE [https://drtrishleigh.com/] - 0:00 Is Porn Addiction Even Real? 1:14 The Smoking-Industry Playbook 2:45 Dopamine Dependency And Reinforcement Loops 4:49 Why Age Eight Is The Real Danger 5:59 Is Fitness Content Pseudo-Porn? 9:42 What Healthy Dopamine Looks Like 13:02 The Loneliness Loop 17:47 Strain Brain vs Drain Brain 21:04 Why You Keep Relapsing 25:46 Cold Plunges And Earning Dopamine 35:16 What "Regulated" Really Means 44:34 Porn And Erectile Dysfunction 54:53 Men vs Women And The Stats 1:01:18 A Message For Anyone Struggling 1:05:15 Protecting Kids From Screens

29. juni 20261 h 15 min