18VC Podcast - Next Gen Builders
Most cold emails get a 1% reply rate and eat three hours of your day. Manuel David dropped out of Arizona State, moved to a San Francisco he'd never set foot in, and built Paradigm, an AI that runs the entire outbound cycle, from finding the lead to booking the meeting on your calendar. On this episode of 18VC, we sit down with Manuel David, founder & CEO of Paradigm Outreach, on why the whole outbound system is broken (not your copy), the infrastructure moat that nobody wants to build, and why he wants the next foundation model to be as powerful as possible. Highlights & Key Insights: * Why Paradigm deliberately rejects ~70% of signups at the door – and why he likes it that way * The contrarian take that "sounding like AI" was never the real problem – it's who you target * "Bring the best model out – all it does is make my product better": his answer to the moat question every AI founder dreads * The Apollo → Instantly → HubSpot slog he collapsed into one conversation with an agent named Parry * Why he started as an email-infrastructure company and how that became the hardest moat to copy * The line he refuses to cross: the AI will never take the meeting for you * The word he'd use to describe himself that has nothing to do with what he's building Timestamps: (00:00) Highlight reel (00:38) Intro (01:27) Meet Manuel & Paradigm (02:27) From an ASU dorm room to founder (04:35) Why he dropped out (07:23) Is college outdated? (07:52) The cold email problem (1% reply rates) (09:44) Is the whole outbound system broken? (11:28) Volume vs. reaching the right person (16:00) The "offer guru" that rejects 70% of signups (18:16) Multi-agent orchestration & the feedback loop (19:16) Selling the result vs. the tool (24:52) Apollo + Instantly vs. one platform (27:58) Deterministic, AI, and where humans stay (29:11) Why "sounding AI" isn't the real problem (32:53) Blueprints & opinionated software (37:07) How Paradigm differs from Boardy (39:11) Finding the right lead across 100+ APIs (40:19) Dogfooding, and the pivot to a distribution engine (41:48) The moat when the next model drops (47:19) A world where everyone has an AI SDR (50:55) The 6–12 month vision (52:46) Faith, and betting on himself (54:48) His biggest mistake as a founder (56:24) Advice for student founders Subscribe for the earliest signal on the founders worth watching. — Connect with Manuel David — LinkedIn: https://www.linkedin.com/in/manuel-david-3b6245328/ [https://www.linkedin.com/in/manuel-david-3b6245328/] X: https://x.com/Manny2techy?s=20 [https://x.com/Manny2techy?s=20] — Paradigm Outreach — Website: https://paradigmoutreach.com/ [https://paradigmoutreach.com/] LinkedIn: https://www.linkedin.com/company/paradigm-outreach/ [https://www.linkedin.com/company/paradigm-outreach/] X: https://x.com/useparadigm [https://x.com/useparadigm] — Connect with 18VC — 18VC Website: https://www.18-vc.com/ [https://www.18-vc.com/] 18VC Podcast on Spotify: https://open.spotify.com/show/6b3YoAMLjZLziwqHWy3EXb [https://open.spotify.com/show/6b3YoAMLjZLziwqHWy3EXb] 18VC Podcast on YouTube: https://youtube.com/@18vcpodcast?si=l69vI6hHwLgIvw4N [https://youtube.com/@18vcpodcast?si=l69vI6hHwLgIvw4N] 18VC Instagram: https://www.instagram.com/18venturecapital/ [https://www.instagram.com/18venturecapital/] 18VC LinkedIn: https://www.linkedin.com/company/eighteenvc/ [https://www.linkedin.com/company/eighteenvc/] 18VC X: https://x.com/Official18VC [https://x.com/Official18VC]
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