Are You Really Allergic to Penicillin? (Update)

Are You Really Allergic to Penicillin? (Update)

Like tens of millions of people, Stephen Dubner thought he had a penicillin allergy. Like the vast majority, he didn’t. This misdiagnosis costs billions of dollars and causes serious health problems, so why hasn’t it been fixed? We find out in this update of a 2025 episode.   * SOURCES: * Kimberly Blumenthal [https://www.mayo.edu/research/faculty/blumenthal-kimberly-g-m-d-m-sc/bio-20591688], allergist-immunologist and researcher at the Mayo Clinic. * Theresa MacPhail [https://theresamacphail.com/], associate professor of science and technology studies at Stevens Institute of Technology. * Thomas Platts-Mills [https://uvahealth.com/findadoctor/Thomas-Platts-Mills-1649395674], professor of medicine at the University of Virginia. * Elena Resnick [https://profiles.mountsinai.org/elena-s-resnick], allergist and immunologist at Mount Sinai Hospital.   * RESOURCES: * Allergic: Our Irritated Bodies in a Changing World [https://amzn.to/4h9Atj2], by Theresa MacPhail (2023). * "Evaluation and Management of Penicillin Allergy: A Review [https://jamanetwork.com/journals/jama/article-abstract/2720732]," by Erica S. Shenoy, Eric Macy, and Theresa Rowe (JAMA, 2019). * "The Allergy Epidemics: 1870–2010 [https://pmc.ncbi.nlm.nih.gov/articles/PMC4617537/]," by Thomas Platts-Mills (The Journal of Allergy and Clinical Immunology, 2016). * "Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy [https://www.nejm.org/doi/full/10.1056/NEJMoa1414850]," by George Du Toit, Graham Roberts, et al. (The New England Journal of Medicine, 2015).   * EXTRAS: * "The Freakonomics Radio Guide to Getting Better [https://freakonomics.com/the-freakonomics-radio-guide-to-getting-better/]," series by Freakonomics Radio (2026). * "Doctors Know They Prescribe Too Many Antibiotics. Why Don’t They Stop? [https://freakonomics.com/podcast/doctors-know-they-prescribe-too-many-antibiotics-why-dont-they-stop/]" by Freakonomics, M.D. (2022). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.

How a Great Architect Thinks, with Bjarke Ingels | Better in Person

Is the oxymoron really “the secret sauce to everything”? That’s the case Ingels makes in this debut episode of our new video show Better in Person, filmed in Stephen Dubner’s living room.   If you'd like to see the video version of Better in Person, watch it on YouTube [https://www.youtube.com/playlist?list=PLI41BDm88y6Q] or Apple Podcasts [https://apple.co/4fh5p1o]. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.

681. How to Host a Talk Show, with Dick Cavett

Stephen Dubner had an idea for a new project. So he drove to Connecticut and knocked on the door of the master. Dubner’s new TV talk show Better in Person launches July 14 on the Freakonomics YouTube channel.   * SOURCES: * Dick Cavett [https://www.youtube.com/@TheDickCavettShow], writer, former talk show host.   * RESOURCES: * Eye on Cavett [https://amzn.to/4vRhiC2], by Dick Cavett and Christopher Porterfield (1983). * Cavett [https://amzn.to/4f4s1C9], by Dick Cavett and Christopher Porterfield (1974). * "The Dick Cavett Show" YouTube Channel [https://www.youtube.com/@TheDickCavettShow]. * "Better in Person" Trailer [https://www.youtube.com/watch?v=GY2oa7DZ1BQ]. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.

680. Can Universities Win Back Our Trust?

Dartmouth president Sian Beilock, a psychologist by training, made her name studying why people choke. Now she’s applying those insights to one of the most scrutinized jobs in America. No pressure!   * SOURCES: * Sian Beilock [https://president.dartmouth.edu/about/people/sian-leah-beilock], president of Dartmouth College.   * RESOURCES: * "Growing share of Americans say the U.S. higher education system is headed in the wrong direction [https://www.pewresearch.org/short-reads/2025/10/15/growing-share-of-americans-say-the-us-higher-education-system-is-headed-in-the-wrong-direction/]," by Kim Parker (Pew Research Center, 2025). * "Standardized Test Scores and Academic Performance at Ivy-Plus Colleges, [https://www.nber.org/papers/w33570]" by John N. Friedman, Bruce Sacerdote, Douglas O. Staiger, and Michele Tine (NBER, 2025). * "Americans’ Trust in One Another [https://www.pewresearch.org/2025/05/08/americans-trust-in-one-another/]," by Laura Silver, Scott Keeter, Stephanie Kramer, Jordan Lippert, Sofia Hernandez Ramones, Alan Cooperman, Chris Baronavski, and Bill Webster (Pew Research Center, 2025). * Choke: What the Secrets of the Brain Reveal About Getting It Right When You Have To [https://amzn.to/4vMqUya], by Sian Beilock (2011)   * EXTRAS: * "Why Does Vanderbilt Keep Winning? [https://freakonomics.com/podcast/why-does-vanderbilt-keep-winning/]" by Freakonomics Radio (2026). * "'A Low Moment in Higher Education [https://freakonomics.com/podcast/a-low-moment-in-higher-education/],'" by Freakonomics Radio (2024). * "'If We’re All in It for Ourselves, Who Are We?' [https://freakonomics.com/podcast/if-were-all-in-it-for-ourselves-who-are-we/]" by Freakonomics Radio (2024). * "Why We Choke Under Pressure (and How Not To) [https://freakonomics.com/podcast/why-we-choke-under-pressure-and-how-not-to/]," by Freakonomics Radio (2018). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.

679. Why Does Vanderbilt Keep Winning?

It’s a hard time to run a university: public trust is low, political pressure is high, and finances are fragile. But Daniel Diermeier, who trained as a political scientist, has Vanderbilt humming. How? He says the key is choosing magnets over wedges.   * SOURCES: * Daniel Diermeier [https://www.vanderbilt.edu/chancellor/biography-diermeier/], chancellor of Vanderbilt University.   * RESOURCES: * "Higher Ed’s New Crisis Managers [https://www.chronicle.com/article/higher-eds-new-crisis-managers]," by Lee Gardner (The Chronicle of Higher Education, 2026). * "Professors Need to Diversify What They Teach [https://www.persuasion.community/p/we-analyzed-university-syllabi-theres]," by Jon Shields, Yuval Avnur, and Stephanie Muravchik (Persuasion, 2025). * "A Call for Constructive Engagement [https://www.aacu.org/newsroom/a-call-for-constructive-engagement]," (American Association of Colleges and Universities, 2025). * "2020 Statement on Anthropology and Human Rights [https://americananthro.org/advocacy-statements/2020-statement-on-anthropology-and-human-rights/]," (American Anthropological Association, 2020). * The New Jim Crow: Mass Incarceration in the Age of Colorblindness [https://amzn.to/43Yzf5w], by Michelle Alexander (2010). * "Kalven Committee: Report on the University’s Role in Political and Social Action [https://provost.uchicago.edu/sites/default/files/documents/reports/KalvenRprt_0.pdf]," (The University of Chicago, 1967).   * EXTRAS: * Sign up here [https://docs.google.com/forms/d/e/1FAIpQLSdMQ0RUWCXYQNI0sdz2kj46nOL-diutRkjJ8WxJIXp0n2EHaA/viewform] to pre-screen our new video show. * "'A Low Moment in Higher Education [https://freakonomics.com/podcast/a-low-moment-in-higher-education/],'" by Freakonomics Radio (2024). * "'If We’re All in It for Ourselves, Who Are We?' [https://freakonomics.com/podcast/if-were-all-in-it-for-ourselves-who-are-we/]" by Freakonomics Radio (2024). * "Do Boycotts Work? [https://freakonomics.com/podcast/do-boycotts-work/]" by Freakonomics Radio (2016). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.