How your metabolism could alter your mental health

How your metabolism could alter your mental health

In 2009, medical student Shebani Sethi [https://med.stanford.edu/profiles/shebani-sethi] watched a patient in a weight loss program make a remarkable recovery. The dietary intervention she underwent alleviated her schizophrenia symptoms, something the woman had tried – and failed – to treat with medication for years. That experience sent Shebani down a medical path that would lead her to treating mental health in a radically different way. Today host Emily Kwong [https://www.npr.org/people/767284140/emily-kwong] talks to Shebani about the emerging field of metabolic psychiatry and how ketogenic metabolic therapy may treat schizophrenia, bipolar disorder and depression. Read Shebani’s article on metabolic psychiatry here [https://www.nature.com/articles/s44220-026-00609-5]. Interested in more lifestyle science? Email us your question at shortwave@npr.org [shortwave@npr.org]. Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org [http://plus.npr.org/] See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. NPR Privacy Policy [https://www.npr.org/about-npr/179878450/privacy-policy]

AI-made viruses could be the future of medicine

The era of AI-generated viruses is here. Some scientists are using AI to design viruses that can attack bacteria. The hope is that these tailor-made viruses can fight drug-resistant bacterial infections in people. And longer-term, Brian Hie, the Stanford researcher spearheading this project, hopes that AI can help create more complicated biological systems to treat formidable diseases. But some experts warn that placed in the wrong hands, this technology could create the next pandemic.  Interested in more AI-related research? Email us your question at shortwave@npr.org [shortwave@npr.org]. Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org [http://plus.npr.org].  See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. NPR Privacy Policy [https://www.npr.org/about-npr/179878450/privacy-policy]

How much has the U.S.’s wildlife changed since Lewis and Clark?

Ever wish you could have been part of the Lewis and Clark expedition? Us too. The Corps of Discovery came across scores of plants and animals that were new to Western science: Grizzly bears, ponderosa pines, a “barking squirrel” that William Clark would later call the prairie dog. A modern effort is underway to see how much the country’s wildlife has changed in the 220-some years since their journey. Host Nate Rott [https://www.npr.org/people/348779465/nathan-rott] tags along with some scientists re-surveying a part of the expedition’s route in western Montana. And he wishes he was in better shape. Interested in more science in the news? Email us your question at shortwave@npr.org [shortwave@npr.org]. Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org [http://plus.npr.org/]. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. NPR Privacy Policy [https://www.npr.org/about-npr/179878450/privacy-policy]

Why scientists are stoked about mysterious black hole stars

You've heard of black holes. You've heard of stars. But have you heard of the newly discovered black hole stars that may explain multiple mysteries of the universe? We just did and we're honestly freaking out about it. Learn everything you need to know about it in this episode. Plus, hear some other cool stories fresh off the presses: Which exercise can help reduce your risk of dementia and how shrews shrink — and then regrow — parts of their body throughout the year. Interested in hearing more reporting on space, scientific mysteries or other emerging science? We want to know! Email us what you'd like us to talk about at shortwave@npr.org [shortwave@npr.org]! Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org [http://plus.npr.org/]. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. NPR Privacy Policy [https://www.npr.org/about-npr/179878450/privacy-policy]

More men are taking testosterone. What gives?

If you’re a guy – or even just friends with a guy – and on the Internet, you may have noticed that testosterone discourse is everywhere. There’s Defense Secretary Pete Hegseth announcing testosterone screenings for soldiers, Joe Rogan discussing hormone therapy, and influencers discussing high- and low-T levels. Those levels affect more than just sex. They also affect metabolism, bone health, muscle mass, red blood cell production and brain function. NPR science reporter Will Stone [https://www.npr.org/people/919093243/will-stone] took a deep dive into it all: What deficiency looks like in men, what doctors recommend and what the research says about who actually needs testosterone replacement therapy. Interested in hearing more reporting on popular science topics? Email us what you’d like us to cover at shortwave@npr.org [shortwave@npr.org]. Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org [http://plus.npr.org].  See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. NPR Privacy Policy [https://www.npr.org/about-npr/179878450/privacy-policy]