Adventures Through The Mind

Psychedelic researchers James Fadiman and Jordan Gruber discuss microdosing protocols, benefits, current research, and safety considerations. Throughout the interview, you will learn the practical basics of psychedelic microdosing—substances, dosage, frequency and duration, when in the larger arc of our lives, and who would best benefit from microdosing; You will also learn about the benefits of microdosing that Gruber and Faidman discovered in their research, which they describe as A-Z, anorexia to zoster and everything in between—with a particular focus later on in the interview on microdosing for various neurological and mental health conditions like ADHD, TBI, dementia, and depression—as well as for the betterment of well people You’ll also learn some of the issues facing microdosing as a both a practice and a premise— issues like placebo, research design, and the potential dangers of microdosing. Enjoy! 🌀 Website and Episode Show Notes [https://bit.ly/ATTMind197] 📚 Buy their Book, Microdosing for Health, Healing, and Enhanced Performance [https://www.microdosingbook.com/] Video Episode [https://youtu.be/CL2sDQwdZBM]  👈 FULL TOPICS BREAKDOWN AND TIMESTAMPS BELOW ... SUPPORT THE PODCAST 🥰 Support ATTMind and join the community on Patreon  [https://www.patreon.com/c/jameswjesso] 🎧 Sub and Review on Apple Podcasts  [https://www.jameswjesso.com/itunes] 🎧 Sub and Review on Spotify   [https://www.jameswjesso.com/spotify] 👁 Watch and Subscribe on Youtube [https://www.jameswjesso.com/youtube] *** Huge thanks to my patrons on Patreon! In particular, my $23+ patrons; Andreas D, Alex F, Eliz C  And a special thanks to Alex B and Erran S for their generous one-time donations. Other options * Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS [https://www.paypal.com/biz/fund?id=383635S3BKJVS] * Buy some merchandise:  https://www.jameswjesso.com/shop/ [http://https//www.jameswjesso.com/shop/] * More Options: https://www.jameswjesso.com/support [https://www.jameswjesso.com/support] Connect with Me * Bluesky: https://bsky.app/profile/jameswjesso.bsky.social [https://bsky.app/profile/jameswjesso.bsky.social] * Instagram: https://www.instagram.com/attmindpodcast/ [https://www.instagram.com/attmindpodcast/] * Newsletter:  https://www.jameswjesso.com/newsletter [https://www.jameswjesso.com/newsletter] * SubStack: https://substack.com/@jameswjesso [https://substack.com/@jameswjesso] * Telegram Channel:  https://t.me/jameswjesso [https://t.me/jameswjesso] * Integration Coaching: https://www.jameswjesso.com/jesso-private-skype-sessions/ [https://www.jameswjesso.com/jesso-private-skype-sessions/] ... Episode Breakdown * (00:00) Opening * (03:28) A quick request * (05:29) Interview begins * (07:13) What microdosing is, and what it is not * (08:33) the dose range for microdosing * (09:42) Bettering the terminology "Sub-threshold" rather than "sub-perceptual" * (15:00) The substances you can microdose (and those that don't qualify and why) * (18:00) Fadiman and Gruber got their data from "real world evidence" * (20:57) The different microdosing protocols * (28:30) Why people tend to stop microdosing after a while * (30:54) Once isn't enough with microdosing, and here's why * (32:28) How consistent we need to be to see benefits * (37:53) How to time higher doses around microdoses, and vice versa * (40:26) What should "do" and "avoid" to help increase microdosing efficacy * (43:14) The value of parts work while microdosing * (45:54) The 4 things microdosing seems to do that contributes to its wide benefit profile * (49:11) How it is that microdosing seems to be helpful for nearly everything * (52:29) Is microdosing just placebo? * (1:01:45) The benefits of microdosing for already well people * (1:11:12) Patreon thanks and invitation * (1:14:24) Potential interactions between microdosing and the microbiome and the gut-brain axis * (1:20:48) The differences between LSD and Psilocybin microdosing * (1:26:02) Theory vs the real world * (1:32:24) How theories can compromise our ability to understand what is really happening * (1:37:12) San Pedro, ibogaine, and caapi microdosing * (1:45:41) Microdosing for ADHD (a new nighttime protocol) * (1:51:07) Microdosing for mTBI (concussion) * (1:57:41) Microdosing for dementia and palliative care * (2:03:52) Microdosing for fun (social microdosing) * (2:06:49) Microdosing makes the bad thing less bad, and the good things better * (2:08:43) Peri-threshold doses? * (2:12:09) The dangers/concerns for microdosing—heart valve damage, bipolar, tinnitus, anxiety, drug interaction, and tracers * (2:18:22) Follow-up links and socials * (2:20:36) Closing

Author and couple's therapist, Charles Wininger discusses how MDMA can serve as "emotional superglue" for relationships by enhancing empathy, creating safety, and improving communication. He explains how the medicine helps couples move from defensive patterns to vulnerability, allowing them to address underlying fears and reconnect. Check our Wininger's book on MDMA for couples, Listening to Ecstasy: The Transformative Power of MDMA  [https://www.simonandschuster.com/books/Listening-to-Ecstasy/Charles-Wininger/9781644111161] ... This is a clip from 'MDMA for Couples | The Love Doctor, Charley Wininger ~ ATTMind Podcast 138' FULL INTERVIEW * Listen on iTunes [https://podcasts.apple.com/ca/podcast/adventures-through-the-mind/id968927571?i=1000508717961] * Listen on Spotify [https://open.spotify.com/episode/1qFTRvXi81P5iSgaC62EMi?si=e3ac04e6b9664838] * Watch in Video [https://youtu.be/vTKnOQKly9o?si=PhVP5SpysnjDyYzo] * Read the show notes [https://bit.ly/ATTMind138]   SUPPORT THE PODCAST 🥰 Support ATTMind and join the community on Patreon  [https://www.patreon.com/c/jameswjesso] Other options   * Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS [https://www.paypal.com/biz/fund?id=383635S3BKJVS] * Buy some merchandise:  https://www.jameswjesso.com/shop/ [http://https//www.jameswjesso.com/shop/] * More Options: https://www.jameswjesso.com/support [https://www.jameswjesso.com/support] * ▷ Sponsor: HARMONIC ARTS PLANT MEDICINE [https://harmonicarts.ca/JESSO] * Use the promo code JESSO for 15% off your First order   Connect with Me * Bluesky: https://bsky.app/profile/jameswjesso.bsky.social [https://bsky.app/profile/jameswjesso.bsky.social] * Instagram: https://www.instagram.com/attmindpodcast/ [https://www.instagram.com/attmindpodcast/] * Newsletter:  https://www.jameswjesso.com/newsletter [https://www.jameswjesso.com/newsletter] * Substack: https://substack.com/@jameswjesso [https://substack.com/@jameswjesso] * Telegram Channel:  https://t.me/jameswjesso [https://t.me/jameswjesso]

🥰 Support ATTMind and join the community on Patreon [https://www.patreon.com/c/jameswjesso] 💌 Stay In Contact Through Signing Up For James' Newsletter [https://www.jameswjesso.com/newsletter] Video Episode [https://youtu.be/_DcvIB6mQ-c]  👈 We deep dive into psychedelics as treatment for chronic pain with Dr. Alex Bekker, Professor and Chairman of Anaesthesiology at Rutgers New Jersey Medical School. We explore what chronic pain is, how it differs from acute pain, and its connection to maladaptive neuroplasticity. Dr. Bekker unpacks why current treatments often fail and how psychedelics—the classical psychedelics as well as ketamine—may effectively treat otherwise treatment-resistant conditions, as well as some practical advice for chronic pain sufferers. Enjoy! 🌀 Website and Episode Show Notes [https://bit.ly/ATTMind196] FULL TOPICS BREAKDOWN BELOW ... SUPPORT THE PODCAST 🥰 Support ATTMind and join the community on Patreon  [https://www.patreon.com/c/jameswjesso] 🎧 Sub and Review on Apple Podcasts  [https://www.jameswjesso.com/itunes] 🎧 Sub and Review on Spotify   [https://www.jameswjesso.com/spotify] 👁 Watch and Subscribe on Youtube [https://www.jameswjesso.com/youtube] *** Huge thanks to my patrons on Patreon! In particular, my $23+ patrons; Andreas D, Alex F, & Eliz C Special thanks also go to Julie D. for the generous one-time donation Other options * Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS [https://www.paypal.com/biz/fund?id=383635S3BKJVS] * Buy some merchandise:  https://www.jameswjesso.com/shop/ [http://https//www.jameswjesso.com/shop/] * More Options: https://www.jameswjesso.com/support [https://www.jameswjesso.com/support] Connect with Me * Bluesky: https://bsky.app/profile/jameswjesso.bsky.social [https://bsky.app/profile/jameswjesso.bsky.social] * Instagram: https://www.instagram.com/attmindpodcast/ [https://www.instagram.com/attmindpodcast/] * Newsletter:  https://www.jameswjesso.com/newsletter [https://www.jameswjesso.com/newsletter] * SubStack: https://substack.com/@jameswjesso [https://substack.com/@jameswjesso] * Telegram Channel:  https://t.me/jameswjesso [https://t.me/jameswjesso] * Integration Coaching: https://www.jameswjesso.com/jesso-private-skype-sessions/ [https://www.jameswjesso.com/jesso-private-skype-sessions/] ... Episode Breakdown * (0:00) Opening * (4:22) Interview begins * (5:00) The difference between acute pain (nociceptive) and chronic pain * (8:24) Chronic pain as neuropathic sensitization (peripheral and central sensitization) * (11:25) Chronic pain involved disrupted nociceptive neural-inhibitory pathways * (12:36) Chronic pain and neural-inflammatory signals * (14:44) Chronic pain as maladaptive neuroplasticity * (16:56) DMN and chronic pain (maladaptive neuroplasticity) * (19:57) Chronic pain is multifactorial (pain is biopsychosocial, not just biological) * (23:02) Treatments of chronic pain (and why they don't work) * (34:45) Biological treatments are not enough * (37:45) Social factors that reinforce chronic pain * (40:09) Patreon Thanks * (43:12) The mechanisms by which psychedelics may help with chronic pain * (54:29) The role of psychotherapy in psychedelic for chronic pain * (57:44) Psychedelics help us re-learn (and reopen critical learning periods) * (1:06:31) Ketamine for the treatment of chronic pain * (1:14:33) Psychedelic helping to correct our "addition" to pain through increasing our sense of connection * (1:20:51) CLIP potential for psychedelic in chronic pain * (1:23:44) Psychedelics for fibromyalgia * (1:26:05) Psychedelic for cancer-related chronic pain * (1:27:27) Psychedelics for Cluster headaches * (1:27:32) CARD clusters * (1:30:23) Psychedelic for phantom limb pain * (1:31:16) What make James excited and hopeful with psychedelic medicine * (1:34:00) Advice to those suffering for chronic pain (psychedelics and otherwise) * (1:37:58) Follow-up info and socials for Dr. Bekker * (1:39:39) Closing

Matthew Baggott discusses the phenomenon of "losing the magic" with MDMA use, where frequent users experience diminishing therapeutic effects over time, likely due to decreased serotonin transporters in the brain; as well as N-Acetyl Cysteine (NAC) supplementation as a potential avenue for getting the magic back.  ... This is a clip from 'Entactogens, MDMA, and Bringing New Love Drugs To Market | Matthew Baggott ~ ATTMind Podcast 177' FULL INTERVIEW * Listen on iTunes [https://podcasts.apple.com/ca/podcast/adventures-through-the-mind/id968927571?i=1000615392826] * Listen on Spotify [https://open.spotify.com/episode/0knriWRYLrTUbBpW7qGcSW?si=849cebee6f3941cf] * Watch in Video [https://youtu.be/dNvC_RRsfJg] * Read the show notes [https://bit.ly/ATTMind177]   SUPPORT THE PODCAST 🥰 Support ATTMind and join the community on Patreon [https://www.patreon.com/c/jameswjesso]   Other options * Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS [https://www.paypal.com/biz/fund?id=383635S3BKJVS] * Buy some merchandise:  https://www.jameswjesso.com/shop/ [http://https//www.jameswjesso.com/shop/] * More Options: https://www.jameswjesso.com/support [https://www.jameswjesso.com/support] ▷ Sponsor: HARMONIC ARTS PLANT MEDICINE [https://harmonicarts.ca/JESSO] * Use the promo code JESSO for 15% off your First order   Connect with Me * * Bluesky: https://bsky.app/profile/jameswjesso.bsky.social [https://bsky.app/profile/jameswjesso.bsky.social] * Instagram: https://www.instagram.com/attmindpodcast/ [https://www.instagram.com/attmindpodcast/] * Newsletter:  https://www.jameswjesso.com/newsletter [https://www.jameswjesso.com/newsletter] * Substack: https://substack.com/@jameswjesso [https://substack.com/@jameswjesso] * Telegram Channel:  https://t.me/jameswjesso [https://t.me/jameswjesso]

🥰 Support ATTMind and join the community on Patreon [https://www.patreon.com/c/jameswjesso] 💌 Stay In Contact Through Signing Up For James' Newsletter [https://www.jameswjesso.com/newsletter] Video Episode [https://youtu.be/KFODWb-6aVk]  👈 Jerónimo Mazarrasa is Program Director at The International Center for Ethnobotanical Education, Research, and Service [https://www.iceers.org] (also known as ICEERS), which is a non-profit organization dedicated to transforming society’s relationship with Traditional Indigenous Medicines. He is also founder of ICEERS Academy, and creator AyaSafety [https://www.jameswjesso.com/ayasafety], an online course for people interested in increasing the safety of ayahuasca ceremonies. Our interview with Jerónimo is going to explore the vulnerability of increased suggestibility while the influence of ayahuasca (and other psychedelics), and the various harms that can can incur when one's facilitator that suggestibility is not handled with skilful care. Throughout the interview we cover a range of different ways that facilitators can accidentally harm their clients through suggestibility; the relationship between openness and vulnerability; how "caring" and "lack of care" can exist simultaneously; how the isolation and clandestine nature the modern psychedelic underground makes cultural learning difficult; how a facilitator can learn what is harmful, with respect to suggestibility; and how participants can protect themselves from a lack of facilitator care—all with many anecdotes and examples sewn throughout the course of the conversation. Enjoy! 🌀 Website and Episode Show Notes [https://bit.ly/ATTMind195] FULL TOPICS BREAKDOWN BELOW ... SUPPORT THE PODCAST 🥰 Support ATTMind and join the community on Patreon  [https://www.patreon.com/c/jameswjesso] 🎧 Sub and Review on Apple Podcasts  [https://www.jameswjesso.com/itunes] 🎧 Sub and Review on Spotify   [https://www.jameswjesso.com/spotify] 👁 Watch and Subscribe on Youtube [https://www.jameswjesso.com/youtube] *** Huge thanks to my patrons on Patreon! In particular, my $23+ patrons; Andreas D, Ian C, Alex F, Eliz C, Joe A Other options * Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS [https://www.paypal.com/biz/fund?id=383635S3BKJVS] * Buy some merchandise:  https://www.jameswjesso.com/shop/ [http://https//www.jameswjesso.com/shop/] * More Options: https://www.jameswjesso.com/support [https://www.jameswjesso.com/support] Connect with Me * Bluesky: https://bsky.app/profile/jameswjesso.bsky.social [https://bsky.app/profile/jameswjesso.bsky.social] * Instagram: https://www.instagram.com/attmindpodcast/ [https://www.instagram.com/attmindpodcast/] * Newsletter:  https://www.jameswjesso.com/newsletter [https://www.jameswjesso.com/newsletter] * SubStack: https://substack.com/@jameswjesso [https://substack.com/@jameswjesso] * Telegram Channel:  https://t.me/jameswjesso [https://t.me/jameswjesso] * Integration Coaching: https://www.jameswjesso.com/jesso-private-skype-sessions/ [https://www.jameswjesso.com/jesso-private-skype-sessions/] ... Episode Breakdown * (00:00) Opening * (01:04) Introduction * (04:24) AyaSafety [https://www.jameswjesso.com/ayasafety] (code AYATTM for 15% off) * (06:35) Interview begins * (07:58) The AyaSafety Course, explained * (18:07) Suggestibility and why is it a concern with Ayahuasca (and all psychedelics) * (24:21) The relationship between openness and vulnerability, ideology * (28:50) The different ways facilitators can accidentally harm their clients through suggestibility * (30:57) The importance of knowing your limits and referring out * (33:04) The harms of introducing spiritual/religious beliefs to clients under the effects of psychedelics * (36:19) Sharing "visions" with clients can be a violation; tarot as an example of offering intuitions skilfully * (42:05) Claiming external authority, ayahuasca told me that * (47:55) Having a shamanic awakening doesn't mean you should become a shaman * (52:20) Patreon Thanks * (54:10) "Trauma" language can impose detrimental constraints on ayahuasca healing * (57:38) The harms/benefits of a facilitator's unskilful/skilful use of language, and vice versa * (1:00:38) Self-knowledge is essential for facilitators; isolation hinders self-knowledge * (1:06:19) These risks are due to uniquely stark power imbalances * (1:08:26) "Caring" and "lack of care" can exist simultaneously * (1:16:37) How a facilitator learns what is harmful, with respect to suggestibility * (1:22:42) How participants can protect themselves from a lack of facilitator care * (1:33:24) AyaSafety course, details—who it is for, and who it is NOT for * (1:40:35) Outro