Entangled Health
Laís Lopes is an electrochemist, graphene specialist, and co-founder and CTO of Qnity, a Brazilian deep-tech startup building a new kind of molecular sensor, one that reads binding events directly at the electron level, in real blood and plasma, without fluorescent labels or amplification steps. In this conversation, we follow her path from hydrogels to graphene to quantum electrochemistry, and into the lab on a night in 2020 when she took real COVID samples, ran them through her graphene sensor, and couldn't sleep afterwards. We talk about what it means to detect a molecule at attomolar concentrations, roughly one grain of sugar dissolved in an Olympic pool, and why that sensitivity changes what's possible in diagnostics and drug discovery. Laís's team has already demonstrated detection of an Alzheimer's biomarker in blood plasma, head and neck cancer DNA, and dengue and COVID in real clinical samples. Their next step: a multiplexed microfluidic platform for measuring binding affinity in drug discovery pipelines, where small molecules and fragments currently fall below the noise floor of existing tools. And at the edge of all of it: a question neither of us could fully answer. If electron-level coherence is what makes this sensing possible — does that same coherence scale upward through biology? Is health, at some level, a coherence problem too? Laís says she doesn't know. I think that's the most honest and interesting place to leave it. Topics covered: * Quantum capacitance vs. geometric capacitance — and why the distinction matters for sensing * Graphene, peptides, gold interfaces, and impedance spectroscopy * Detecting Alzheimer's biomarkers in blood plasma without lumbar puncture * Why small molecules fall into noise in standard drug discovery assays — and how quantum electrochemistry sidesteps that * Building Qniti: from academic IP to venture-backed deep tech * The coherence bet: electrons, biology, and the question Thomas can't stop asking Host & Guests * Thomas Ehmer [https://entangled-health.transistor.fm/people/thomas-ehmer] - Host Click here to watch a video of this episode. [https://www.youtube.com/watch?v=q1tVuu5NXog] We don't simplify for comfort. We entangle. Submit your questions or propose a guest in the comments, or join the discussion on Substack: https://thomasehmer1.substack.com/ If you like it — thanks for subscribing and leaving a thumbs up wherever you listen 👍 Disclaimer: The views, thoughts, and opinions expressed in this episode are those of the host and guest speaking in their personal capacities and do not necessarily reflect the official policy or position of their respective employers, organizations, committees (including IEEE), or companies. Medical Disclaimer: This podcast is for informational and educational purposes only. The discussion regarding lithium isotopes, biology, and mental health is based on theoretical quantum chemistry and physics, not clinical medical advice. Nothing in this episode should be taken as a recommendation to alter medication or treatment plans. Always seek the advice of your physician or qualified health provider with any questions you may have regarding a medical condition.
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