The GLP-1 Effect: Health and Weight Loss w/ Dr. Lisa Golding-Granado

Calm the F Down (The Parasympathetic Edge for Performance) | Eric Casaburi & Dr. Scott Sherr

In today’s episode, you’re going to hear a conversation that might completely reframe how you think about stress, recovery, performance, and why so many high achievers quietly burn out. Joining Eric is Dr. Scott Sherr, a board certified internal medicine physician specializing in hyperbaric therapy, health optimization medicine, and cellular performance. Together, they unpack what Dr. Sherr calls “the parasympathetic edge” — and why living in constant fight or flight mode is slowly eroding your energy, hormones, sleep, and long term health. This conversation was sparked by a pattern both Eric and Dr. Sherr see every single day: high performing professionals who go hard at the gym, go hard at work, go hard at home — and never downshift. The result isn’t peak performance. It’s nervous system overload. Dr. Sherr explains why exercise itself is a sympathetic stressor, why gains are made during recovery — not during the workout — and how hustle culture has normalized chronic sympathetic activation. Over time, this creates mitochondrial dysfunction, hormone disruption, inflammation, insomnia, brain fog, and eventually breakdown. Eric shares real world examples from years in the fitness industry and longevity space, including what happens when enthusiastic gym members overtrain in January and quit six weeks later. They also explore how to measure nervous system balance through heart rate variability, lab testing, metabolomics, and hormone panels. The conversation then expands into practical recovery strategies, including hyperbaric oxygen therapy, red light therapy, IV support, and targeted supplementation. Dr. Sherr breaks down methylene blue, mitochondrial resilience, altitude stress, and why energy production and oxidative stress must be addressed intelligently within a larger framework. Most importantly, this episode emphasizes foundation over flash. Advanced therapies are powerful tools — but without balancing the nervous system and optimizing cellular health first, even the best modalities fall short. This episode is not about doing more. It is about recovering better. In this episode, you’ll learn: Why sympathetic dominance quietly destroys long term performance What “parasympathetic edge” actually means Why exercise without recovery backfires How overtraining contributes to burnout By the end of this episode, you’ll understand why your biggest performance advantage isn’t pushing harder — it’s learning how to downshift faster. For more resources related to today’s episode, visit: https://agingbackwardgrowingforward.com/ Learn more about Serotonin Centers: https://www.serotonincenters.com/ Follow Eric’s Longevity Lab on Instagram: https://www.instagram.com/ericslongevitylab/ Follow Eric: Instagram and YouTube: https://www.youtube.com/@EricCasaburi/videos TikTok: https://www.tiktok.com/@ericcasaburi Facebook: https://www.facebook.com/profile.php?id=61550518600042 LinkedIn: https://www.linkedin.com/in/ericcasaburi/ Follow Dr. Scott Sherr: Instagram: https://www.instagram.com/drscottsher r/ YouTube: https://www.youtube.com/@TranscendYourHealth Website: https://drscottsherr.com/ I am not a licensed physician, and this podcast is not intended as a substitute for the advice of a physician or other qualified healthcare professional. Always consult with a licensed provider regarding your health decisions. I’ll see you in the next episode. In this episode: 00:00 Why hustle culture is burning people out 02:14 The parasympathetic edge explained 05:03 Why you make gains during recovery, not workouts 07:28 Overtraining and the six week gym dropout pattern 10:02 Measuring nervous system balance with HRV 12:31 Lab testing and metabolomics for optimization 15:10 Recovery modalities that actually work 18:45 Hyperbaric therapy and mitochondrial health 22:07 Methylene blue and cellular energy 27:14 Why foundation matters more than biohacks 33:40 Final lesson: calm down to perform better

Your Health Is Not Transactional (Why Shortcut Hormone Care Fails) | Eric Casaburi

In today’s episode, you’re going to hear a conversation that brings clarity to your health decisions, especially if you’ve been feeling overwhelmed by conflicting advice, tempted by fast results, or unsure who to trust when it comes to hormone therapy and medical weight loss. Joining Eric is a deeply experienced voice in the longevity and hormone optimization space, shaped by years of working directly with individuals navigating hormone replacement therapy, metabolic health, and sustainable optimization. This conversation was sparked by a growing concern Eric has seen firsthand. As hormone therapy and medical weight loss increasingly move online, convenience has gone up while personalization, oversight, and long term thinking have quietly disappeared. What looks simple on the surface often comes with consequences people do not anticipate until later. Eric brings decades of experience and candid insight into why hormones are deeply personal, why one size fits all dosing fails so many people, and why healthcare should never be treated as a transaction. He shares real examples of what happens when follow ups are skipped, muscle loss goes unmeasured, and medications are taken without proper guidance. This episode is an invitation to pause, reset, and rethink how you approach your health. It will help you step back from shortcuts, understand why monitoring and relationships matter, and recognize what responsible, longevity focused care actually looks like. Even if you’ve never considered hormone therapy or medical weight loss, this conversation will change how you think about personalization, safety, and what it truly means to invest in your long term wellbeing. In this episode, you’ll learn: By the end of this episode, you’ll feel more grounded in how to evaluate health decisions, more confident slowing the process down, and clearer on why thoughtful, personalized care matters far more than chasing fast results. For more resources related to today’s episode, visit:https://agingbackwardgrowingforward.com/ [https://agingbackwardgrowingforward.com/] Learn more about Serotonin Centers:https://www.serotonincenters.com/ [https://www.serotonincenters.com/] Follow Eric’s Longevity Lab on Instagram:https://www.instagram.com/ericslongevitylab/ [https://www.instagram.com/ericslongevitylab/] Follow Eric: YouTube:  [https://www.youtube.com/@EricCasaburi/videos]https://www.youtube.com/@EricCasaburi/videos [https://www.youtube.com/@EricCasaburi/videos] TikTok:  [https://www.tiktok.com/@ericcasaburi]https://www.tiktok.com/@ericcasaburi [https://www.tiktok.com/@ericcasaburi] Facebook:  [https://www.facebook.com/profile.php?id=61550518600042]https://www.facebook.com/profile.php?id=61550518600042 [https://www.facebook.com/profile.php?id=61550518600042] LinkedIn:  [https://www.linkedin.com/in/ericcasaburi/]https://www.linkedin.com/in/ericcasaburi/ [https://www.linkedin.com/in/ericcasaburi/] I am not a licensed physician, and this podcast is not intended as a substitute for the advice of a physician or other qualified healthcare professional. Always consult with a licensed provider regarding your health decisions. I’ll see you in the next episode. In this episode: 00:00 The rise of online hormone therapy and medical weight loss ads 00:21 Why hormones are deeply personal and never one size fits all 01:28 The biggest myths about online hormone and weight loss programs 02:47 How improper dosing creates bigger problems over time 03:23 Real examples of dosing mistakes and stalled results 04:31 Why lack of oversight is a serious safety concern 05:10 The importance of follow ups and tracking body composition 05:47 How muscle loss happens during medical weight loss 06:47 When weight loss ages you instead of improving health 08:17 Why weight regain often comes back as fat, not muscle 09:25 The real reason online programs are cheaper 10:55 Why health is a relationship, not a transaction 11:45 What happens after you reach your goal 12:09 Why hormone therapy and medical weight loss are not risk free 13:17 The dangers of unsupervised online medication use 14:44 Why concierge style, in person care changes outcomes 15:13 Investing in your health the right way ● Why hormone therapy and medical weight loss are never one size fits all ● How improper dosing can quietly undermine both results and safety ● Why muscle loss is often overlooked during weight loss ● How lack of follow up creates long term health setbacks

Hormones, Confidence & Aging Well: The Secrets to Feeling Your Best

Episode Description:On this episode of Aging Backward, Growing Forward, Eric welcomes back Kim Casaburi for a deep dive into hormone health, aesthetics, and the emotional journey many women experience during midlife. They discuss the powerful impact of hormone optimization, the rise of the "Menopausal Makeover," and how small lifestyle shifts can lead to major transformations. From personal stories to practical advice, this conversation is a must-listen for anyone looking to reclaim confidence, vitality, and longevity.Episode Breakdown:(00:00 [https://www.youtube.com/watch?v=4dUKHKOBlmk]-04:35 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=275s]) The mindset shift: How changing your mind can change your body(04:36 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=276s]-10:00 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=600s]) Hormone replacement therapy: The science behind feeling and looking younger(10:01 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=601s]-13:15 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=795s]) The "Menopausal Makeover" and why aesthetics start from within(13:16 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=796s]-21:22 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=1282s]) The confidence factor: Why self-care isn’t selfish(21:23 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=1283s]-26:24 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=1584s]) The science of aging: Bone density, sleep, and optimizing your health(26:25 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=1585s]-33:34 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=2014s]) Relationships and hormones: How balancing your health improves your connections(33:35 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=2015s]-34:58 [https://www.youtube.com/watch?v=4dUKHKOBlmk&t=2098s]) Take action: The first step in optimizing your future🔗 Learn more about hormone optimization at Serotonin Centers: serotonincenters.com🎧 Subscribe to the podcast wherever you get your podcasts!📲 Follow Eric Casaburi on Instagram: @ericcasaburiHashtags:#hormonehealth [https://www.youtube.com/hashtag/hormonehealth] #menopausalmakeover [https://www.youtube.com/hashtag/menopausalmakeover] #antiaging [https://www.youtube.com/hashtag/antiaging] #longevity [https://www.youtube.com/hashtag/longevity] #confidence [https://www.youtube.com/hashtag/confidence] #wellness [https://www.youtube.com/hashtag/wellness] #biohacking [https://www.youtube.com/hashtag/biohacking] #hormones [https://www.youtube.com/hashtag/hormones] #womenshealth [https://www.youtube.com/hashtag/womenshealth] #healthyliving [https://www.youtube.com/hashtag/healthyliving] #selfcare [https://www.youtube.com/hashtag/selfcare] #agingwell [https://www.youtube.com/hashtag/agingwell] #hormonebalance [https://www.youtube.com/hashtag/hormonebalance] #wellnessjourney [https://www.youtube.com/hashtag/wellnessjourney] #mindset [https://www.youtube.com/hashtag/mindset] #energy [https://www.youtube.com/hashtag/energy] #fitness [https://www.youtube.com/hashtag/fitness] #healthylifestyle [https://www.youtube.com/hashtag/healthylifestyle]

Finding the Solution: A Journey to Hormone Optimization with Kim Casaburi

In this week's episode, Eric Casaburi interviews his wife, Kim Casaburi, about her transformative journey with hormone replacement therapy and its profound impact on her health and well-being. Kim recounts her struggle with hormone imbalances, the challenges she faced in finding the right treatment, and how hormone replacement therapy significantly improved her physical and emotional symptoms, relationships, and overall quality of life. The conversation also highlights the importance of testosterone for women, emphasizing the need for better education and awareness around hormone health. Beyond sex and beauty, hormone replacement therapy enhances overall fitness, mental well-being, and the health of hair, skin, and nails. Starting therapy early can prevent symptoms from becoming harder to reverse, and optimized hormones are crucial for heart health. Kim underscores the importance of finding a knowledgeable practitioner and getting regular blood work to maintain optimal hormone levels.Takeaways:Discover how hormone replacement therapy can be life-changing for women with hormone imbalances.Learn about the crucial role of testosterone in women's health and its impact on energy, mood, and vitality.Understand the benefits of hormone optimization on physical and mental well-being, including heart health.Gain insights into the importance of starting hormone therapy early and finding the right practitioner for regular monitoring and treatment.Explore how hormone therapy improves overall fitness, hair, skin, and nail health.Chapters:(00:00 [https://www.youtube.com/watch?v=s8Yk82kBPr8]) Introduction: Kim Casaburi, the Inspiration behind Serotonin Brand(02:05 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=125s]) The Journey Begins: Kim's Experience with Hormone Imbalances(08:08 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=488s]) The Search for Answers: Frustrations with Medical Practitioners(10:32 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=632s]) The Importance of Hormone Testing and Hormone Replacement Therapy(23:15 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=1395s]) The Ripple Effect: How Hormone Imbalances Affect Relationships(27:02 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=1622s]) The Transformation: From Cardio to Strength Training(29:08 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=1748s]) The Power of Hormone Health: Beyond Vanity and Beauty(35:29 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=2129s]) Hormone Optimization for Heart Health(39:56 [https://www.youtube.com/watch?v=s8Yk82kBPr8&t=2396s]) Improvements in Sleep and Mental Clarity(44:15) The Importance of Starting Hormone Replacement Therapy Early(50:38) Finding a Knowledgeable Practitioner for Hormone Replacement TherapyHelpful links:Learn more about Eric and Kim's journey by visiting the Serotonin Centers website: Serotonin Centers.Enhance your podcast experience by rating, reviewing, and subscribing.Follow Eric on Instagram for more health tips and updates: Instagram.Don't forget to subscribe to the video podcast on YouTube at YouTube.#HormoneReplacementTherapy [https://www.youtube.com/hashtag/hormonereplacementtherapy] #HealthOptimization [https://www.youtube.com/hashtag/healthoptimization] #TestosteroneForWomen [https://www.youtube.com/hashtag/testosteroneforwomen] #HormoneHealth [https://www.youtube.com/hashtag/hormonehealth] #FitnessAndWellBeing [https://www.youtube.com/hashtag/fitnessandwellbeing] #MentalClarity [https://www.youtube.com/hashtag/mentalclarity] #HeartHealth [https://www.youtube.com/hashtag/hearthealth] #KimCasaburi [https://www.youtube.com/hashtag/kimcasaburi] #EricCasaburi [https://www.youtube.com/hashtag/ericcasaburi] #SerotoninCenters [https://www.youtube.com/hashtag/serotonincenters] #QualityOfLife [https://www.youtube.com/hashtag/qualityoflife] #PersonalizedTreatment [https://www.youtube.com/hashtag/personalizedtreatment] #ProfessionalGuidance [https://www.youtube.com/hashtag/professionalguidance]

The GLP-1 Effect: Health and Weight Loss w/ Dr. Lisa Golding-Granado

In this week's episode, Eric Casaburi interviews Dr. Lisa Golden Granada about the growing impact of GLP-1 agonists and their role in metabolic health. Dr. Gigi shares her experience with these treatments, highlighting their effectiveness in managing diabetes, improving insulin sensitivity, and promoting weight loss. The conversation delves into the science behind GLP-1 agonists and their potential to enhance overall health, including heart health and metabolic function. Dr. Gigi stresses the importance of combining therapy with lifestyle changes for optimal results and lasting benefits.Takeaways:Discover how GLP-1 agonists can transform metabolic health.Learn about the crucial role of insulin sensitivity in managing weight and diabetes.Understand the long-term health benefits of GLP-1 therapy, including improved heart health.Gain insights into the importance of pairing GLP-1 treatment with exercise and nutrition.Explore how GLP-1 therapy can support sustainable weight loss and metabolic balance.Chapters:(00:00 [https://www.youtube.com/watch?v=BPmcmS4av5k]) Introduction: Dr. Lisa Golden Granada(02:05 [https://www.youtube.com/watch?v=BPmcmS4av5k&t=125s]) Understanding GLP-1 Agonists and Their Role in Health(08:08 [https://www.youtube.com/watch?v=BPmcmS4av5k&t=488s]) GLP-1’s Impact on Weight Loss and Diabetes Management(10:32 [https://www.youtube.com/watch?v=BPmcmS4av5k&t=632s]) The Science Behind GLP-1 Agonists and Insulin Sensitivity(23:15 [https://www.youtube.com/watch?v=BPmcmS4av5k&t=1395s]) How GLP-1 Agonists Support Long-Term Heart and Metabolic Health(27:02 [https://www.youtube.com/watch?v=BPmcmS4av5k&t=1622s]) The Importance of Lifestyle Changes with GLP-1 Therapy(35:29) Enhancing the Benefits of GLP-1 Agonists with Exercise and Nutrition(39:56) How GLP-1 Agonists Improve Energy and Well-being(44:15) The Future of GLP-1 Therapy in Health Optimization(50:38) Finding the Right Practitioner for GLP-1 TreatmentHelpful links:Learn more about Eric and Dr. Gigi’s discussion by visiting the Serotonin Centers website: Serotonin Centers.Enhance your podcast experience by rating, reviewing, and subscribing.Follow Eric on Instagram for more health tips and updates: Instagram.Subscribe to the video podcast on YouTube at YouTube.#GLP1Therapy [https://www.youtube.com/hashtag/glp1therapy] #HealthOptimization [https://www.youtube.com/hashtag/healthoptimization] #MetabolicHealth [https://www.youtube.com/hashtag/metabolichealth] #WeightLossJourney [https://www.youtube.com/hashtag/weightlossjourney] #GLP1Benefits [https://www.youtube.com/hashtag/glp1benefits] #InsulinSensitivity [https://www.youtube.com/hashtag/insulinsensitivity] #EricCasaburi [https://www.youtube.com/hashtag/ericcasaburi] #DrGigi [https://www.youtube.com/hashtag/drgigi] #SerotoninCenters [https://www.youtube.com/hashtag/serotonincenters] #DiabetesManagement [https://www.youtube.com/hashtag/diabetesmanagement] #PersonalizedTreatment [https://www.youtube.com/hashtag/personalizedtreatment] #HealthyLiving [https://www.youtube.com/hashtag/healthyliving]