Can Clinical Trials Rise Faster Without Losing Their Flavor?

The Confounding Case of Skin Cancer and Sunscreen

On this week's episode, we look into one of the key benefits of clinical trials: that they tend to isolate against confounding variables. We look at what confounding variables are and look at the long-term example of reported links between sunscreen use and increased skin cancer rates. We look at why excessive sun exposure is dangerous, how sunscreen works, why rates of skin cancer appeared to increase as sunscreen was introduced. Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released. Follow us on Social Media: Facebook [https://www.facebook.com/MedEvidence] Instagram [https://www.instagram.com/med_evidence/] Twitter [https://x.com/Med_Evidence] LinkedIn [https://www.linkedin.com/company/medevidence] Tiktok [https://www.tiktok.com/@medevidence.com] Youtube [https://youtube.com/@MedEvidence] For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.com [https://medevidence.com/] Thank you for listening!

Can Clinical Trials Rise Faster Without Losing Their Flavor?

In this episode, we’re talking about the FDA’s push toward real-time clinical trials, and what that could mean for the pace, quality, and oversight of bringing new treatments to patients. Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released. Follow us on Social Media: Facebook [https://www.facebook.com/MedEvidence] Instagram [https://www.instagram.com/med_evidence/] Twitter [https://x.com/Med_Evidence] LinkedIn [https://www.linkedin.com/company/medevidence] Tiktok [https://www.tiktok.com/@medevidence.com] Youtube [https://youtube.com/@MedEvidence] For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.com [https://medevidence.com/] Thank you for listening!

What Avocados and FibroScan Teach Us About Liver Health

In this episode, we look at the need for cheap, accurate screening tools for common diseases. To that end, we take the example of fatty liver disease. We review the "gold standard" diagnostic tool, liver biopsy, and why that shouldn't be the first line of detection for a fatty liver. We review some standard methods of screening before diving into transient elastography, also known as FibroScan. We look at what this method is, why it may be preferable to an MRI or CT scan, and how clinical researchers use transient elastography in trials. Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released. Follow us on Social Media: Facebook [https://www.facebook.com/MedEvidence] Instagram [https://www.instagram.com/med_evidence/] Twitter [https://x.com/Med_Evidence] LinkedIn [https://www.linkedin.com/company/medevidence] Tiktok [https://www.tiktok.com/@medevidence.com] Youtube [https://youtube.com/@MedEvidence] For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.com [https://medevidence.com/] Thank you for listening!

The Mental and Physical Toll of PCOS

In this week's episode, guest author Maya Yanchuck explores the ins and outs of PCOS. We review what the condition is, symptoms, complications, and what is happening in the body. Finally, we look at treatments, from mental health to medicaitons. Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released. Follow us on Social Media: Facebook [https://www.facebook.com/MedEvidence] Instagram [https://www.instagram.com/med_evidence/] Twitter [https://x.com/Med_Evidence] LinkedIn [https://www.linkedin.com/company/medevidence] Tiktok [https://www.tiktok.com/@medevidence.com] Youtube [https://youtube.com/@MedEvidence] For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.com [https://medevidence.com/] Thank you for listening!

The Brain’s Hidden Vulnerability: How Misinformation Rewires What We Believe

In this week's episode, written by guest author Christy Kestner, we explore the neuroscience of misinformation. We look inot what misinformation is, what happens inside the brain when we encounter misinformation, why misinformation can be so hard to correct, and some of the real-life consequences with misinformation - especialyl in relation to health. We close by discussing how we can combat misinformation, from correcting false ideas to protecting against inflammatory, misleading informaiton found online. References: * Bragazzi NL, Garbarino S. Understanding and combating misinformation: An evolutionary perspective. JMIR infodemiology. 2024 Dec 27;4(1):e65521. https://doi.org/10.2196/65521 [https://doi.org/10.2196/65521] * Piksa M, Noworyta K, Gundersen A, Kunst J, Morzy M, Piasecki J, Rygula R. The impact of confirmation bias awareness on mitigating susceptibility to misinformation. Frontiers in Public Health. 2024 Oct 15;12:1414864. https://doi.org/10.3389/fpubh.2024.1414864 [https://doi.org/10.3389/fpubh.2024.1414864] * Hassan A, Barber SJ. The effects of repetition frequency on the illusory truth effect. Cognitive research: principles and implications. 2021 May 13;6(1):38. https://doi.org/10.1186/s41235-021-00301-5 [https://doi.org/10.1186/s41235-021-00301-5] * Schultz W. Dopamine reward prediction error coding. Dialogues in clinical neuroscience. 2016 Mar 31;18(1):23-32. https://doi.org/10.31887/DCNS.2016.18.1/wschultz [https://doi.org/10.31887/DCNS.2016.18.1/wschultz] * Chau LS, Galvez R. Amygdala's involvement in facilitating associative learning-induced plasticity: a promiscuous role for the amygdala in memory acquisition. Frontiers in integrative neuroscience. 2012 Oct 10;6:92. https://doi.org/10.3389/fnint.2012.00092 [https://doi.org/10.3389/fnint.2012.00092] * Vellani V, Zheng S, Ercelik D, Sharot T. The illusory truth effect leads to the spread of misinformation. Cognition. 2023 Jul 1;236:105421. https://doi.org/10.1016/j.cognition.2023.105421 [https://doi.org/10.1016/j.cognition.2023.105421] * Chan MP, Jones CR, Hall Jamieson K, Albarracín D. Debunking: A meta-analysis of the psychological efficacy of messages countering misinformation. Psychological science. 2017 Nov;28(11):1531-46. https://doi.org/10.1177/0956797617714579 [https://doi.org/10.1177/0956797617714579] Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released. Follow us on Social Media: Facebook [https://www.facebook.com/MedEvidence] Instagram [https://www.instagram.com/med_evidence/] Twitter [https://x.com/Med_Evidence] LinkedIn [https://www.linkedin.com/company/medevidence] Tiktok [https://www.tiktok.com/@medevidence.com] Youtube [https://youtube.com/@MedEvidence] For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.com [https://medevidence.com/] Thank you for listening!