My Weird Prompts

Does Your DNA Change Over a Lifetime?

30 min · 14 de jun de 2026
Portada del episodio Does Your DNA Change Over a Lifetime?

Descripción

Is DNA a static blueprint or a living document? This episode unpacks the surprising ways your genetic code changes over a lifetime. We break down the difference between somatic mutations and germline mutations, revealing why a father’s age at conception directly impacts the number of new mutations passed to a child. We also explore the dynamic world of epigenetics—the chemical “dimmer switches” that respond to diet and stress—and whether those changes can be inherited. Finally, we trace the history of DNA discovery, from Friedrich Miescher’s 1869 extraction from pus-soaked bandages to the landmark 1944 Avery experiment and the famous 1953 double helix revelation. It’s a deep dive into the fluid, edited nature of the molecule that makes you, you.

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Does Your DNA Change Over a Lifetime?

Is DNA a static blueprint or a living document? This episode unpacks the surprising ways your genetic code changes over a lifetime. We break down the difference between somatic mutations and germline mutations, revealing why a father’s age at conception directly impacts the number of new mutations passed to a child. We also explore the dynamic world of epigenetics—the chemical “dimmer switches” that respond to diet and stress—and whether those changes can be inherited. Finally, we trace the history of DNA discovery, from Friedrich Miescher’s 1869 extraction from pus-soaked bandages to the landmark 1944 Avery experiment and the famous 1953 double helix revelation. It’s a deep dive into the fluid, edited nature of the molecule that makes you, you.

14 de jun de 202630 min