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Dr. Josh Kellog is an assistant professor at the Department of Biomolecular Sciences at Pennsylvania State University in the US. He works as an ethnobotanist: working with indigenous cultures around the world to find drugs from nature. Today, he talks to us about his experiences on the ground and how the field has changed over the years. To learn more about Dr. Kellogg's work, visit: https://scholar.google.com/citations?user=ebu0_H8AAAAJ Timeline: 00:00 Introduction 03:38 Selecting Plants to Study 06:03 Extracting Medicinal Compounds 09:03 Problem Solving with Pharmaceuticals 12:42 His lab's work 14:49 History of Ethnobotany 18:53 Favourite Field Lessons 23:23 Challenges for Indigenous Cultures 25:28 Innovations in Ethnobotany 29:13 Neglected Areas P.S. Some fancy words Dr. Kellogg used: - Activity: how much a chemical can influence biological organisms - Bioassay guided fractionation: a process of repeatedly separating chemicals in a sample to isolate one desired chemical. Like a drug candidate. - Pathogenic: harmful to humans - US CDC: The US Centre for Disease Control. A government organisation to manage public health risks. - Penicillin: the first antibiotic drug to be produced at global scale. - Toxicology studies: Studies to test whether a certain substance is harmful to biological organisms and at what dose. - Clinical tries: a series of tests to prove that a drug is beneficial to patients. - Nuclear Magnetic Resonance Imaging: A tool that chemists use to identify molecules by the magnetic properties of their electrons. - Mass spectrometry: A tool that chemists use to identify molecules by their atomic mass.
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