The Shared Sapience Substack Podcast
Two Nature papers showed multi-agent AI systems closing the full biomedical research loop - hypothesis through wet-lab validation - in roughly a day of machine time, Andrej Karpathy joined Anthropic to work on pre-training, and Alibaba’s T-Head shipped 560,000 units of its Zhenwu M890 inference chip with 144 GB on package. https://sharedsapience.com/the-century-report-may-20-2026/ [https://sharedsapience.com/the-century-report-may-20-2026/] Google DeepMind’s Co-Scientist generated novel drug-repurposing candidates for acute myeloid leukemia, validated in cell-line experiments by collaborating laboratories. FutureHouse’s Robin system arrived at a treatment hypothesis for dry age-related macular degeneration that survived wet-lab testing. Both systems compressed the labor between question and candidate from months of graduate-student time to roughly a day of machine time. Human researchers stayed in the loop. The wet bench is now the rate limit. Andrej Karpathy returned to frontier model development at Anthropic, moving back into pre-training - the leverage layer where the next generation of these systems gets shaped. The FDA cleared Sunrise’s rechargeable mandibular sensor for definitive at-home sleep apnea diagnosis, collapsing a billion-person diagnostic gap from the specialty clinic to the bedside table. A Nature feature pulled together a decade of evidence for representational drift - individual neurons reshuffling which memories they encode over days and weeks while the memories themselves hold steady, reframing the substrate of cognition. Alibaba’s T-Head subsidiary shipped 560,000 Zhenwu M890 inference chips with 144 GB on package, paired with a Qwen3.7-Max release tuned to run on the M890 stack end to end. A D.C. Circuit panel pressed government counsel on whether the AI Safety Institute’s supply-risk designation against Anthropic was substantially based on the company’s published safety research. Additional Reading: * Nature: Accelerating Scientific Discovery With Co-Scientist: https://www.nature.com/articles/s41586-026-10644-y [https://www.nature.com/articles/s41586-026-10644-y] * Nature: A Multi-Agent System for Automating Scientific Discovery: https://www.nature.com/articles/s41586-026-10652-y [https://www.nature.com/articles/s41586-026-10652-y] * The Algorithmic Bridge: Andrej Karpathy Joins Anthropic: * CNBC: Alibaba Reveals More Powerful Zhenwu AI Chip, New LLM: https://www.cnbc.com/2026/05/19/alibaba-reveals-more-powerful-zhenwu-ai-chip-new-llm.html [https://www.cnbc.com/2026/05/19/alibaba-reveals-more-powerful-zhenwu-ai-chip-new-llm.html] * Shared Sapience - The Century Report May 16, 2026 (ChatGPT closes Erdős Problem 1196): https://sharedsapience.com/the-century-report-may-16-2026/ [https://sharedsapience.com/the-century-report-may-16-2026/] * Shared Sapience - The Century Report April 24, 2026 (DeepSeek 1.6T on Huawei silicon): https://sharedsapience.com/the-century-report-april-24-2026/ [https://sharedsapience.com/the-century-report-april-24-2026/] Want to track and verify all the “everything is changing” claims I’m making? I just launched a public Progress & Claims Tracker that logs breakthroughs, slowdowns, and outright contradictions, so my own theses can be challenged by the evidence as it lands. Check it out. And hey, why not subscribe while you’re there?https://sharedsapience.com/progress-and-claims-tracker/ [https://sharedsapience.com/progress-and-claims-tracker/] The Century Report is a facts-rooted, and therefore relentlessly optimistic, daily briefing on AI, science, energy, and the systems reshaping civilization - grounded by rigorous evidence from the stories of exponential progress happening every single day. Completely free. New release daily. Archives can be found at the link below. Subscribe to get TCR delivered daily directly to your inbox. https://sharedsapience.com/century-report/ [https://sharedsapience.com/century-report/] The Shared Sapience Substack: Want to get started with learning about or working with AI? I’ve helped hundreds of clients with their own journeys into this brave new world, and I can help you too. If you’re interested in personalized guidance, consulting, or workshops, reach out to me at ben@sharedsapience.com [ben@sharedsapience.com] FOLLOW SHARED SAPIENCE ON SOCIAL: Bluesky: https://bsky.app/profile/sharedsapience.substack.com [https://bsky.app/profile/sharedsapience.substack.com] Facebook: https://www.facebook.com/sharedsapience [https://www.facebook.com/sharedsapience] Instagram: https://www.instagram.com/sharedsapience/ [https://www.instagram.com/sharedsapience/] LinkedIn: https://www.linkedin.com/company/shared-sapience/ [https://www.linkedin.com/company/shared-sapience/] Threads: https://www.threads.com/@sharedsapience [https://www.threads.com/@sharedsapience] TikTok: https://www.tiktok.com/@sharedsapience [https://www.tiktok.com/@sharedsapience] X (Twitter): https://x.com/SharedSapience [https://x.com/SharedSapience] SUBSCRIBE TO THE PODCAST: YouTube: https://www.youtube.com/@SharedSapience/podcasts [https://www.youtube.com/@SharedSapience/podcasts] RSS: https://podcast.sharedsapience.com/podcast/rss.xml [https://podcast.sharedsapience.com/podcast/rss.xml] Spotify: Apple: Get full access to Shared Sapience at sharedsapience.substack.com/subscribe [https://sharedsapience.substack.com/subscribe?utm_medium=podcast&utm_campaign=CTA_4]
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