The Soaak Podcast
#42: Heart disease often develops silently for years — and many people don’t realize they’re at risk until a major event happens. In this Part 2 episode, host Aaron Fournier sits down with Dr. Paul Harris to break down how cardiovascular disease really forms, why chronic low-grade inflammation is now considered a central driver (not just cholesterol), and what “stealth” heart disease looks like long before symptoms appear. You’ll learn why 60–70% of heart attack patients can have normal cholesterol, how inflammation damages the endothelial lining of arteries, and why plaque instability — not just plaque presence — is what creates real danger. Dr. Harris explains the step-by-step process of plaque formation (including oxidized LDL, macrophages, and foam cells), how calcification can worsen the situation, and why nitric oxide regulation matters for blood flow, blood pressure, cognition, and overall vascular performance. We also connect major hidden drivers that fuel cardiovascular inflammation, including: * Oral health and cardiovascular risk (p. gingivalis) * Gut permeability, LPS, and brain inflammation * Oxidative stress and “oxidized LDL” * Insulin resistance, belly fat, and metabolic inflammation * Genetics like APOE variants and cardiovascular risk Finally, Dr. Harris shares proactive testing options that can uncover risk earlier than standard cholesterol panels — including markers like hs-CRP, IL-6, homocysteine, ApoB-related markers, and imaging tools like calcium scoring and CCTA. If you want to understand heart disease before it becomes an emergency — this episode lays out a clearer model for prevention, early detection, and smarter decision-making. 00:00 Introduction 03:12 It’s Not Cholesterol 06:24 Inflammation Markers 09:36 What Causes Inflammation 12:48 Oral Health Link 16:00 Homocysteine + MTHFR 19:12 Bloodwork To Request 22:24 60,000 Miles Vessels 25:36 Paradigm Shift Medicine 28:48 Inflammaging Explained 32:00 Mitochondria + Oxidative 35:12 Fasting + Autophagy 38:24 Oxidized LDL Danger 41:36 Lifestyle Inflammation Triggers 44:48 Gut-Brain-Heart Axis 48:00 Plaque Formation Steps 51:12 Calcium Score Testing 54:24 Advanced Cardio Panel Reach Dr. Harris: Call (918)551-6600, and ask for Debbie or Stephanie Follow Soaak & The Science of Sound Podcast: * Website – Soaak Technologies [https://www.soaak.com/app] * App – Soaak Frequency Therapy [https://app.soaak.com/] * Instagram – @thesoaakpodcast [https://www.instagram.com/soaakpodcast?igsh=NTc4MTIwNjQ2YQ==] Sponsors: Visit soaak.com/app [http://soaak.com/app] and enter code Soaakpod for your first month free! Produced by Soaak Technologies Inc. [https://www.soaak.com/]
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