Evidence-Based GI: An ACG Publication and Podcast

Ellen Axenfeld, MD and Elie Al Zazzi, MD, MPH discuss "Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Peyrin-Biroulet L, et al and the ARTEMIS-UC Study Group. Published in N Engl J Med. 2024 Sep 26;391(12):1119-1129.

Rachael Hagen, MD and Joseph C. Anderson, MD, FACG discuss "Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer,” by Jacobson BC, Anderson JC, Burke CA, Dominitz JA, Gross SA, May FP, Patel SG, Shaukat A, Robertson DJ. Published in Am J Gastroenterol. 2025: 120(4):738-764.

Editor-in-Chief Paul Y. Kwo, MD, FACG and Associate Editor Elie S. Al Kazzi, MD, MPH discuss "Tofacitinib in acute severe ulcerative colitis (TACOS): A randomized controlled trial," by Singh A, Goyal MK, Midha V, et al. Am J Gastroenterol 2024; 119 (7), 1365-1372.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence," by O'Sullivan T, Mandarino FV, Gauci JL, et al. Gut. 2024 Dec 10;74(1):67-74.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Germline CDH1 variants and lifetime cancer risk,” by Ryan CE, Fasaye G, Gallanis AF, et al. JAMA. 2024;332(9):722–729.