Huberman Lab

The Best Vitality & Health Protocols | Dr. Rhonda Patrick

Dr. Rhonda Patrick, PhD, is a biomedical scientist and public science educator. She shares the exercise, nutrition, supplementation and lifestyle practices linked to better health and lower disease risk including specific cardio and resistance training routines, when and why to do intermittent fasting, ways to lower visceral fat, omega-3 sourcing, creatine for brain and muscle and peptides such as BPC-157. It’s broad and thorough coverage of how to build a total health program tailored to your goals and individual biology. Read the show notes at hubermanlab.com [https://www.hubermanlab.com/episode/the-best-vitality-and-health-protocols-rhonda-patrick]. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] Our Place: https://fromourplace.com/huberman [https://fromourplace.com/huberman] Lingo: https://hellolingo.com/huberman [https://hellolingo.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] Function: https://functionhealth.com/huberman [https://functionhealth.com/huberman] Mateina: https://drinkmateina.com/huberman Timestamps 00:00:00 Rhonda Patrick (00:02:40) Competition, Jumping Rope, Rope Flow (00:06:49) Rhonda's Exercise Routine, Cardiovascular & Resistance Training (00:12:30) Cognitive & Physical Benefits of Exercise, Serotonin & Impulse Control (00:14:40) Sponsors: Our Place & Lingo (00:17:03) Phones While Training? (00:18:45) Rhonda's Strength Training, Low-Reps, Modifications, Mental Resilience (00:27:00) Daily Protein Intake, Intermittent Fasting, Processed Carbohydrates (00:33:32) Lipopolysaccharide (LPS); Gut Permeability, Gluten; Cardiovascular Health (00:42:58) Sponsor: AG1 (00:44:21) Tight Junctions, Gut, Neuroinflammation (00:47:26) L-glutamine, Immune System, Cancer Risk (00:54:55) N-acetylcysteine (NAC), Vitamin E; Antioxidant Balance, Reductive Stress (01:00:08) Starch, Tool: Bedtime Fast & Cardiovascular Health (01:03:36) Cortisol, Intermittent Fasting Benefits (01:08:09) Cortisol, Train Fasted?; Hormones, Visceral Fat (01:13:35) Visceral Fat, Perimenopause/Menopause, Insulin Resistance in Brain & Body (01:21:13) Sponsor: LMNT (01:22:33) Cortisol & Sleep (01:25:42) Intermittent Fasting, Metabolic Switch, Ketones, Muscle Loss? (01:36:47) Tools: Logic-Based Habits; Daily Metabolic Switch; Exercise, Autophagy (01:45:06) Exercise After Poor Sleep?; Training Breaks (01:52:47) Tool: "Exercise Snacks"; Sedentary Lifestyle & Cardiorespiratory Fitness (02:03:31) Sponsor: Function (02:05:16) Creatine, Dose, Resistance Training, Cognitive Function (02:17:43) Biology; Creatine; Supplement Safety (02:25:18) Omega-3s, Inflammation, Cancer Risk, Vitamin D; Trans Fat (02:36:52) Magnesium Threonate vs Bisglycinate, Sleep, Cognitive Benefit; Vitamin D (02:45:46) Supplement Types, Multivitamin, Coenzyme Q10, Urolithin A, Sulforaphane (02:55:10) Microplastics (02:57:26) Sponsor: Mateina (02:58:28) BPC-157, NMN, NR, Tool: Evaluating Supplements, Safety, Sources (03:06:28) L-Carnitine, Alpha-GPC, Nicotine, GABA & Ketogenic Diet (03:15:20) Nattokinase; Microplastics, Water Bottles; Seed Oils (03:22:21) Sauna, Creatine for Kids?, Bananas, Tool: Evaluating Studies (03:28:37) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Essentials: Tools for Setting & Achieving Goals | Dr. Emily Balcetis

In this Huberman Lab Essentials [https://www.hubermanlab.com/essentials] episode, my guest is Dr. Emily Balcetis, PhD, a professor of psychology at New York University who studies how visual perception influences motivation and goal pursuit. She explains how to better visualize and overcome challenges to achieve physical or cognitive goals. We also explore the science of setting goals, measuring progress effectively and research showing how fitness level and energy state can shape how difficult the world appears. Read the episode show notes at hubermanlab.com [https://www.hubermanlab.com/episode/essentials-tools-for-setting-and-achieving-goals-emily-balcetis]. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] BetterHelp: https://betterhelp.com/huberman [https://betterhelp.com/huberman] Timestamps (00:00:00) Emily Balcetis (00:00:21) Adjusting Vision to Meet Goals, Exercise, Tool: Narrow Visual Target (00:07:39) Sponsor: Eight Sleep (00:08:57) Goal Setting, Do Vision Boards Work? (00:12:34) Tool: Effectively Plan Goals, Plan for Obstacles (00:17:58) Sponsor: AG1 (00:19:23) How Fitness Shapes the Way People See the World (00:24:46) Visual Spotlight, Exercise & Physical Fitness Level (00:25:45) Stimulants & Motivation (00:27:06) Sponsor: BetterHelp (00:28:20) Cognitive Goals, Tools: Overcoming Bad Memories; Deadlines (00:35:31) Acknowledgements Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Science-Based Meditation Tools to Improve Your Brain & Health | Dr. Richard Davidson

Dr. Richard Davidson, PhD, is a professor of psychology and psychiatry at the University of Wisconsin–Madison and a pioneer in the scientific study of meditation. We discuss how meditation changes your brain and body, how just 5 minutes daily can improve focus, stress resilience and your overall health, and we cover different types of meditation. We also address common myths such as the idea that meditation is to "clear your mind." And we discuss common challenges with meditation and how to overcome them. This episode offers both the science and the practical tools to build a consistent meditation practice to improve your mental and physical health and help you flourish. The episode show notes are available at hubermanlab.com [https://www.hubermanlab.com/episode/science-based-meditation-tools-to-improve-your-brain-and-health-richard-davidson]. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] David: https://davidprotein.com/huberman [https://davidprotein.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] Joovv: https://joovv.com/huberman [https://joovv.com/huberman] Waking Up: https://wakingup.com/huberman [https://wakingup.com/huberman] Timestamps (00:00:00) Richard "Richie" Davidson (00:03:33) States of Mind vs Traits (00:09:06) Wakeful Brain Activity vs Deep Sleep (00:11:55) Sponsors: David & Eight Sleep (00:14:31) Brain Activity Across Sleep, Wakefulness, Meditation & Insight (00:19:27) Mediation & Sleep Compensation?; Meditation Timing & Liminal States (00:23:05) Types of Mediation, Shifting from Thinking to Being (00:28:32) Self-Monitoring, Undistracted Non-Mediation, "Stickiness" (00:35:30) Tool: Beginning Daily Meditation, "Richie's 5 Meditation"; Health Benefits (00:39:39) Meditation Practice History, Kindness & Nurturing Goodness (00:45:07) Sponsor: AG1 (00:46:31) Beginners, Expect Chaos in Mind, Exercise & Lactate Analogy (00:52:47) Tool: Beginning Mediation, Embrace Anxiety; Meta-Awareness, Flow (00:57:51) Creativity; Capturing Thoughts, Unconscious Mind (01:03:03) Meditation for Kids; Flourishing, Tool: Parent & Teacher Meditation (01:10:12) Sponsor: Joovv (01:11:34) Beyond Stimulus & Response (01:14:22) Meditation Need; Gaining Insight Into Mind, Transcendence (01:18:00) Contemplating Death, Long-Term Meditation (01:21:33) Richie's Meditation Practice; Tools: Pairing Meditation, Appreciation Practice (01:26:07) Consistency, Balancing Discipline vs Surrender (01:29:52) Social Media & Validating Existence, Digital Hygiene (01:37:31) Meditation & Impulsivity; Discipline & "No Go's", Phone (01:42:08) Physical Discomfort & Pain During Meditation; Retreat Practice (01:46:50) Phone Detox, Self-Control (01:52:07) Sponsor: Waking Up (01:53:29) Overcoming Resistance, Making Peace With Your Mind (01:58:37) Meditation & Connectivity; Consistency, Prayer; Sleepiness; Meta-Awareness (02:05:49) Tools: Pillars of Flourishing; Appreciation Practice, Loving-Kindness Practice (02:15:39) Awareness & Insight, Tools: Outside View; Task Connection (02:19:43) Cultivating Flourishing, Familiarity with Resistance (02:25:23) Psychedelics, Guides, Clinical vs Non-Clinical Use (02:32:15) Neuromodulation & Meditation, Sleep; Tool: Pre-Sleep Meditation (02:37:25) Open Monitoring Meditation & Creativity (02:41:12) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Essentials: Benefits of Sauna & Deliberate Heat Exposure

In this Huberman Lab Essentials [https://www.hubermanlab.com/essentials] episode, I discuss the mechanisms through which deliberate heat exposure enhances both physical and mental health. I outline specific protocols for deliberate heat exposure, including recommended temperature ranges, frequency, timing, duration and sauna alternatives. In addition, I explain how to tailor your heat protocols to support your specific goals, such as increasing growth hormone, reducing cortisol or supporting cognitive health. Read the show notes at hubermanlab.com [https://www.hubermanlab.com/episode/essentials-benefits-of-sauna-and-deliberate-heat-exposure]. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] Timestamps (00:00:00) Heat Exposure (00:00:47) Shell vs Core Temperature; Heat Caution & Hyperthermia (00:02:24) Body & Brain Circuit to Heat Up & Cool Down (00:05:31) Sponsor: AG1 (00:06:55) Deliberate Heat Exposure & Health Benefits; Tool: Sauna Temperature Range, Duration, Frequency (00:112:09) Sauna Types, Alternatives to Sauna (00:13:50) Sauna Mechanism; Reduced Cortisol; Tool: Hot/Cold Contrast (00:17:38) Sponsor: LMNT (00:19:10) Heat Shock Protein Activation & Sauna (00:20:50) DNA Repair, FOXO3 & Sauna, Cognition & Health Benefits (00:24:21) Sauna & Increase Growth Hormone (00:30:18) Sponsor: Eight Sleep (00:31:36) Sauna Timing, Sleep & Growth Hormone, Tools: Fasting; Hydration (00:34:56) Improve Mood, Endorphins & Sauna; Dynorphins (00:40:04) Recap Sauna Protocols: Benefits, Frequency, Duration & Timing [https://www.hubermanlab.com/disclaimer] Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson

Dr. Alex Marson, MD, PhD, is a Senior Investigator at the Gladstone Institutes and a professor of medicine at the University of California, San Francisco. We discuss the biology of the immune system and cancer, and everyday choices that can increase or decrease your cancer risk, several of which are surprising but all of which are actionable. We also discuss immunotherapy, including how engineered T-cells can be used to defeat childhood and adult cancers. Dr. Marson explains CRISPR and gene editing to cure diseases, and we address the ethical questions surrounding gene editing in embryos, children and adults. This discussion is for anyone interested in avoiding cancer and/or seeking to understand the science and practical applications of immune- or gene-therapy. Read the show notes at hubermanlab.com [https://www.hubermanlab.com/episode/avoiding-treating-and-curing-cancer-with-the-immune-system-alex-marson]. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] BetterHelp: https://betterhelp.com/huberman [https://betterhelp.com/huberman] Helix Sleep: https://helixsleep.com/huberman [https://helixsleep.com/huberman] LMNT: https://drinklmnt.com/huberman [https://drinklmnt.com/huberman] Function: https://functionhealth.com/huberman [https://functionhealth.com/huberman] Timestamps (00:00:00) Alex Marson (00:02:21) Diseases & Current Biological Landscape; AI & Computational Tools (00:05:56) Immune System, Innate vs Adaptive Immune System (00:10:55) Thymus, T Cell Selection; B Cells & Antibodies (00:13:23) Sponsors: BetterHelp & Helix Sleep (00:16:11) Immune System Health, Sleep, Diet; Genes (00:20:56) Childhood Exposure & Allergy Prevention; Autoimmune Reactions (00:25:27) Whole Body Immune Response, Cytokines & Fever; Antibiotics (00:30:51) Cancer; Mutations & Cell Regulation; Smoking, BRCA Mutations, Sunlight (00:38:27) BRAC Mutations, Mutagens, Pesticides (00:42:33) Sponsor: AG1 (00:43:57) X-Rays & Airport Scanners, Carcinogen vs Mutagen, Charred Meat, Food Dye (00:49:34) Immune-Based Cancer Treatment, Checkpoint Inhibitors, CAR T-Cell Therapy (00:59:04) CRISPR, Immunotherapies (01:02:52) Age & Cancer Risk; CAR T-Cells, Targets & Side Effects; Ketogenic Diet (01:08:27) CRISPR Discovery & Mechanism (01:17:06) CRISPR Precision, Risk & Benefit; CRISPR Technology Evolution (01:20:57) Sponsor: LMNT (01:22:17) CRISPR Cell Delivery, Clinical Trials; Treating Early Cancers & Prevention (01:33:47) Liposomes, Engineered Viruses, Lipid Nanoparticles (LNPs), Vaccines (01:39:57) COVID Pandemic & Trust in Science, mRNA Vaccine (01:47:51) Sponsor: Function (01:49:39) Drug Delivery to Cancer, Immunotoxins, T-Cell Engagers; AI Protein Targets (01:55:45) CRISPR Embryo Modification, Ethics; Heritable Gene Editing, Diversity (02:05:42) Deep Sequencing Embryos, Diversity; Overcoming Adversity & Resilience (02:10:44) Upcoming Therapeutics, Autoimmunity & CAR T-Cells, CRISPR & Gene Function (02:17:55) Banking T Cells or iPSCs?, Future of Cell Programming (02:24:41) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]