The Hunter Williams Podcast

Get My Book On Amazon: https://a.co/d/avbaV48 Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/ Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/ 👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here 1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/ Book A Call With Me: https://hunterwilliamscall.carrd.co/ Supplement Sources: https://hunterwilliamssupplements.carrd.co/ Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY Socials: Instagram: https://www.instagram.com/hunterwilliamscoaching/ Podcast: https://hunterwilliamspodcast.buzzsprout.com/ Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ Curious about the pros, cons, and real-world protocols for using human growth hormone (HGH) and growth hormone peptides together? In this video, I share my personal experience, the science, and practical cycling strategies for optimizing results—whether your goal is fat loss, muscle growth, or longevity. Timestamps 0:00 – Introduction & Why I’m Updating This Topic 1:00 – My Core Belief: HGH Is the Gold Standard (But Peptides Have a Place) 1:42 – What Are Growth Hormone Peptides? GHRPs vs GHRHs Explained 2:20 – HGH vs Peptides: The Core Difference 2:58 – Why Use HGH? My Personal Experience and When It’s Best 3:53 – How Exogenous HGH Works (and the Pituitary Shutdown Question) 4:53 – Peptide Types: GHRH vs GHRP (and Why It Matters) 5:28 – The Science of Peptide Synergy: Why Combine Peptides? 7:19 – What Happens When You Stack Peptides (CJC+Ipamorelin) 8:02 – Key Benefits: Lean Muscle, Fat Loss, Recovery, and More 9:04 – Fat Loss: How HGH and Peptides Each Work 10:37 – Recovery, Sleep, Skin, and Cognitive Benefits 12:11 – Metabolic and Cardiovascular Benefits 13:01 – Comparing HGH and Peptides Head-to-Head 14:33 – Risks: Side Effects of HGH vs Peptides 15:58 – Accessibility, Cost, and Dosing Frequency 16:56 – My Favorite Protocols: How I Cycle HGH and Peptides 17:31 – How to Alternate and Combine for Maximum Effect 18:19 – Pulsatile Therapy, Circadian Rhythm, and Optimizing Results 19:11 – Example Yearly Cycle: How I Use HGH and Peptides Throughout the Year 20:49 – Why You Need to Experiment for Yourself (Personalization is Key) 22:02 – Final Thoughts, Gratitude, and How to Ask Me Questions What you’ll learn in this video:  • The real science and mechanism behind HGH and growth hormone peptides  • My honest protocol for stacking and cycling both for best results  • When to use just peptides, just HGH, or both together  • How to avoid side effects and get the best from your regimen  • My seasonal “real-life” cycling strategy for year-round progress Want the full peptide cheat sheet and exclusive protocols? Check the link below. And join our Fully Optimized Health community to nerd out with 700+ other biohackers. Drop your questions in the comments—I read them all!

Get My Book On Amazon: https://a.co/d/avbaV48 Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/ Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/ 👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here 1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/ Book A Call With Me: https://hunterwilliamscall.carrd.co/ Supplement Sources: https://hunterwilliamssupplements.carrd.co/ Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY Socials: Instagram: https://www.instagram.com/hunterwilliamscoaching/ Podcast: https://hunterwilliamspodcast.buzzsprout.com/ Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ Are you thinking about switching from tirzepatide to retatrutide? In this video, I’ll walk you through everything you need to know about making the transition—from the science and mechanisms, to real-world dosing strategies and the side effect differences I see in my community. If you’re looking for maximum fat loss and the most up-to-date peptide protocols, this video is for you. Timestamps 0:00 – Introduction: Why the switch from tirzepatide to retatrutide is happening 0:45 – Clinical background: Compounding issues and the rising popularity of retatrutide 1:30 – My transition philosophy: Gradual tapering and best practices 2:04 – Mechanisms: How tirzepatide and retatrutide work in the body 3:10 – Tirzepatide: GIP and GLP-1 agonism explained 3:54 – Why tirzepatide has fewer side effects vs semaglutide 4:01 – Retatrutide: What does triple agonism mean? 4:42 – Metabolic advantages: Glucagon receptor activation, liver fat reduction, energy expenditure 5:45 – Head-to-head comparison: Why retatrutide is stronger for fat loss 6:51 – Dose escalation: How to titrate both drugs (side effects & protocol) 7:56 – Study outcomes: Average weight loss on both drugs 9:10 – A1C improvements: Comparing metabolic health markers 10:00 – Retatrutide’s liver benefits and impact on longevity 11:02 – What to expect when you switch: Side effects, hunger, and adaptation 12:02 – Appetite differences: Why tirzepatide suppresses appetite more at equal doses 13:30 – Side effect management: GI symptoms, heart rate, and tips 14:02 – My detailed titration schedule for switching safely 16:50 – Can you mix tirzepatide and retatrutide? 17:39 – Why minimum effective dosing matters and other fat loss pathways 18:01 – Final thoughts: Community support, feedback, and closing In this video you’ll learn:  • The step-by-step protocol to taper down tirzepatide and introduce retatrutide safely  • Key differences in mechanisms (GIP/GLP-1 vs GIP/GLP-1/Glucagon)  • Real world data on weight loss, A1C, and fatty liver reduction  • My honest recommendations for side effect management  • How to listen to your body and titrate up for maximum effect  • Answers to common questions: can you combine both, and is the switch right for you?

Get My Book On Amazon: https://a.co/d/avbaV48 Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/ Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/ 👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here 1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/ Book A Call With Me: https://hunterwilliamscall.carrd.co/ Supplement Sources: https://hunterwilliamssupplements.carrd.co/ Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY Socials: Instagram: https://www.instagram.com/hunterwilliamscoaching/ Podcast: https://hunterwilliamspodcast.buzzsprout.com/ Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ Are you struggling to balance estrogen while on testosterone? In this video, I break down the surprising connection between metformin and estrogen, why blocking estrogen is NOT the answer, and how metformin may be the healthiest aromatase inhibitor nobody talks about. 0:00 - Introduction: Why Metformin vs Estrogen? 0:45 - The Real Cause of High Estrogen in Men 1:48 - My Experience: High Testosterone, No Estrogen Problems 2:57 - Why Metformin May Beat Aromatase Inhibitors 4:36 - Disclaimer & Perspective 5:00 - Understanding Aromatase in Fat Tissue 6:06 - Obesity, Aromatase, and Hormones 9:06 - Metformin’s Effect on Aromatase: What Science Says 11:12 - Metformin: Selective Estrogen Control in Fat 13:11 - Beyond Fat: Metformin in Ovaries & Lungs 15:57 - How Metformin Modulates Aromatase (Molecular Pathways) 17:46 - Metformin, Insulin, and Aromatase: The Hidden Link 19:05 - Metformin’s Anti-Inflammatory Impact on Estrogen 20:42 - The Power of Reducing Visceral Fat with Metformin 22:45 - Metformin’s Crosstalk with Estrogen Receptors 23:47 - Consequences of Altered Aromatase Activity 25:08 - PCOS, Reproduction, and Metformin’s Role 26:57 - Metformin, Estrogen, and Metabolic Health 28:29 - Summing Up: Metformin as an Estrogen Modulator 29:08 - Walking the Estrogen Tightrope: Real World Takeaways 31:18 - Case Studies & Community Discussion 32:36 - Thank You & Final Thoughts In this deep-dive, I explain why most men don’t have an “estrogen problem”—they have a visceral fat problem. More fat means more aromatase, which means more testosterone gets converted into estrogen. I share my experience taking high doses of testosterone (up to 750 mg/week!) with no high-estrogen symptoms, because I keep visceral fat low. You’ll learn why metformin can act as a natural aromatase modulator, helping to manage estrogen not by blocking it, but by fixing the upstream problems: insulin resistance, inflammation, and excess body fat. I break down the science, studies, and mechanisms: from AMPK activation, to anti-inflammatory effects, to tissue-specific aromatase control in fat, ovaries, and lungs. We’ll cover what the research says about metformin lowering estrogen only when it’s pathologically high (like in obesity, PCOS, or inflammation) while keeping healthy estrogen levels intact. If you’re using testosterone, battling estrogen issues, or worried about aromatase inhibitors’ side effects, this video will show you a healthier, smarter way forward—backed by science and my own clinical experience. Let me know in the comments if you’ve tried replacing your AI with metformin, or if you’re curious to experiment!

Get My Book On Amazon: https://a.co/d/avbaV48 Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/ Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/ 👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here 1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/ Book A Call With Me: https://hunterwilliamscall.carrd.co/ Supplement Sources: https://hunterwilliamssupplements.carrd.co/ Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY Socials: Instagram: https://www.instagram.com/hunterwilliamscoaching/ Podcast: https://hunterwilliamspodcast.buzzsprout.com/ Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ Are you struggling with chronic fatigue, brain fog, or mysterious autoimmune symptoms? Mold toxicity is one of the most underdiagnosed yet widespread health issues today—and most people don’t even realize it’s the real cause behind their suffering. In this in-depth video, I, Hunter Williams, break down my ultimate peptide stack for mold toxicity, explaining exactly how each peptide works, the clinical evidence, recommended dosages, and how you can use these strategies to reclaim your health. Timestamps 0:00 – Introduction: Why Mold Toxicity Is So Prevalent   1:02 – How to Test for Mold Exposure & My North Carolina Story   3:33 – What Peptides Help with Mold? Full Stack Overview   4:22 – LL-37: The Antimicrobial Powerhouse   8:32 – SS-31: The Mitochondrial Repair Peptide   12:51 – Thymosin Alpha 1 (TA1): Immune Restoration   17:36 – Thymalin: Bioregulator Peptide for Immune Balance   22:18 – BPC-157: Regeneration & Gut Healing   26:31 – TB-500: Repair and Recovery for Mold-Induced Damage   31:58 – KPV: Anti-Inflammatory & Mast Cell Stabilizer   37:12 – VIP: The Critical Peptide for True Mold Recovery   43:16 – Dosage Chart & Protocol (Screenshot This!)   43:38 – Final Thoughts: Healing Mold Toxicity with Peptides   44:55 – Mold Toxicity Is More Common Than You Think   45:17 – Why Most People Don’t Know They Have Mold Issues   45:22 – Closing & Thank You   In this video, you’ll learn:  • The root causes and hidden dangers of mold toxicity  • How to test for mold exposure (no fluff, just practical steps)  • Why testosterone optimization matters for mold recovery  • How each peptide (LL-37, SS-31, TA1, Thymalin, BPC-157, TB-500, KPV, VIP) helps with immune balance, inflammation, and tissue repair  • Clinical evidence, practical dosing, and real-world application  • My personal recommendations based on years of research and coaching Whether you’ve been diagnosed with mold illness, chronic fatigue, CIRS, or you’re just biohacking for better health, this comprehensive guide will walk you through everything you need to know about using peptides to recover from mold exposure. Screenshot the protocol chart at [43:16] for easy reference! 👇 Share your experience with mold and peptides in the comments below—your story could help someone else heal! Don’t forget to like, subscribe, and download my free Peptide Cheat Sheet for more advanced protocols.

Get My Book On Amazon: https://a.co/d/avbaV48 Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/ Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/ 👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here 1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/ Book A Call With Me: https://hunterwilliamscall.carrd.co/ Supplement Sources: https://hunterwilliamssupplements.carrd.co/ Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY Socials: Instagram: https://www.instagram.com/hunterwilliamscoaching/ Podcast: https://hunterwilliamspodcast.buzzsprout.com/ Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/ In this video, I dive deep into the reasons behind the infamous “GLP plateau”—that frustrating point where fat loss on GLP-1 peptides like semaglutide, tirzepatide, and retatrutide comes to a grinding halt. I break down the physiological, hormonal, and lifestyle factors that drive plateaus, plus practical, science-backed solutions to get results moving again. ⸻ Timestamps 0:00 – Introduction: Why Do GLP-1 Plateaus Happen? 0:35 – Why Weight Loss Plateaus Are Universal 1:22 – How GLP-1s Work (Mechanisms: Semaglutide, Tirzepatide, Retatrutide) 2:36 – Typical Weight Loss Trajectory on GLP-1s 3:18 – When (and Why) Most People Plateau 4:55 – Plateau ≠ Failure: The New Weight Set Point 5:39 – Physiological & Metabolic Causes of Plateaus 6:26 – Resting Metabolic Rate Drop & Adaptive Thermogenesis 7:31 – Decreased Thermogenesis, Exercise Efficiency, & Mitochondria 8:42 – Muscle Loss and Its Impact on Plateaus 9:44 – NEAT (Non-Exercise Activity Thermogenesis) Drops 10:18 – Why the Body Adapts: Our Ancestral Survival Mechanism 11:06 – Hormonal Adaptations: Leptin, Ghrelin, Insulin 13:03 – Leptin Drop: Increased Hunger, Lower Metabolism 13:41 – Ghrelin Rise: Appetite Returns 15:17 – Insulin, Metabolic Health & Fat Loss 17:20 – Thyroid Hormones: T3, Metabolic Rate, and the Plateau 19:03 – Cortisol, Stress, and Fat Storage 20:07 – Sex Hormones: Testosterone, Fat Loss, and Plateaus 21:46 – Amylin, Neuropeptide Y, and Brain Pathways 22:44 – Behavioral & Lifestyle Factors: NEAT, Adherence, Calorie Creep 24:44 – Psychological Fatigue, Sleep, Diet Quality, & Hydration 28:27 – Is It a True Plateau? Body Fat vs. Weight Loss 28:32 – Pharmacological Tolerance & Dosing Issues 30:00 – Appetite Pathways and Receptor Desensitization 31:52 – Dose Ceiling: When More Isn’t Always Better 33:26 – Strategies to Break Through a Plateau 34:16 – Re-evaluating Diet: Macros, Sugar Diet, and Tracking 34:45 – Activity, Resistance Training, and NEAT 35:03 – Sleep, Stress, Thyroid, and Other Medications 35:44 – Add-On Pharmacology: LDN, Cagrilintide, Leptin Analogs 37:01 – Mitochondrial Pathways: BAM15, SLU-PP-332, Carnitine 37:50 – Cycling, Refeeds, and Metabolic Resensitization 39:55 – Fasting, Intermittent Fasting, and Nutrition 40:08 – Recap: Everyone Plateaus—How Will You Respond? 41:02 – Thank You & Outro