This Week in Virology

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. Hosts: Vincent Racaniello [https://en.wikipedia.org/wiki/Vincent_Racaniello], Rich Condit [https://mgm.ufl.edu/profile/condit-rich/], and Angela Mingarelli Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Support science education  [http://www.microbe.tv/contribute]at MicrobeTV * ASV 2025 [http://asv.org/asv2025] * Committee of experts to counter vaccine misinformation [https://www.science.org/content/article/vaccine-experts-band-together-counter-u-s-government-misinformation] (Science) * NSF Director [https://www.science.org/content/article/nsf-director-resign-amid-grant-terminations-job-cuts-and-controversy] resigns (Science) * Dependence of vaccine immune response on gut microbiome [https://www.sciencedirect.com/science/article/abs/pii/S193131282500126X?via%3Dihub] (Cell Host Microbe) * Nucleosome switch [https://www.cell.com/cell/abstract/S0092-8674(25)00102-3?rss=yes] primes HepB replication (Cell) * Letters read [https://www.microbe.tv/twiv/twiv-1213-letters/] on TWiV 1212 * Timestamps by Jolene [https://ramseylab.vercel.app/] Ramsey. Thanks! Weekly Picks Angela – Wild chimpanzees filmed by scientists bonding over alcoholic fruit [https://www.theguardian.com/science/2025/apr/21/wild-chimpanzees-filmed-by-scientists-bonding-over-alcoholic-fruit?utm_source=chatgpt.com] Rich – Malcolm Gladwell Revisionist History “The Joe Rogan Intervention” [https://www.pushkin.fm/podcasts/revisionist-history/the-joe-rogan-intervention] Vincent –  [https://www.nature.com/articles/d41586-025-01108-w]Measles Misinformation Is on the Rise — and Americans Are Hearing It, Survey Finds [https://www.medscape.com/s/viewarticle/measles-misinformation-rise-and-americans-are-hearing-it-2025a10009yg?src=rss&form=fpf] Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deplore the US’s withdrawal from the global health community for pandemic preparedness i.e. the universal avian flu vaccine, and undermining the use of routine childhood vaccinations for pertussis and measles, RFK’s autism registry, yellow fever outbreak in Colombia and world immunization week after discussing the squirrel as the reservoir host for mpox, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, how immunity elicited by the RSV vaccine wanes in 3 years, if Paxlovid reduces stroke, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, if vaccination impacts long COVID and if long COVID were to become epidemic. Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * The American Public’s Disengagement [https://ajph.aphapublications.org/doi/abs/10.2105/AJPH.2025.308080?journalCode=ajph] With Highly Pathogenic Avian Influenza (HPAI): Considerations for Vaccination and Dietary Changes(American Public Health Association) * New agreement geared toward universal avian flu vaccine [https://www.cidrap.umn.edu/new-agreement-geared-toward-universal-avian-flu-vaccine] (CIDRAP) * Cambridge’s DIOSynVax and Singapore’s ACM Biolabs to advance pandemic-ready universa [https://www.globenewswire.com/news-release/2025/04/22/3065588/0/en/Cambridge-s-DIOSynVax-and-Singapore-s-ACM-Biolabs-to-Advance-Pandemic-Ready-Universal-Bird-Flu-Vaccine-with-International-Support.html]l bird flu vaccine with international support (GlobeNewswire) * Bird flu continues to spread among live poultry markets [https://www.crainsnewyork.com/health-pulse/bird-flu-continues-spread-among-live-poultry-markets] after shut down order  (CRAIN’S New York Business) * Fire-footed rope squirrels (Funisciurus pyrropus) are a reservoir host [https://www.researchsquare.com/article/rs-6322223/v1] of monkeypox virus (Orthopoxvirus monkeypox)(Research Square) * It is a squirrel! An animal source of mpox [https://www.nature.com/articles/d41586-025-00990-8?WT.ec_id=NATURE-20250417&utm_source=nature_etoc&utm_medium=email&utm_campaign=CONR_41586_AWA1_GL_DTEC_054CI_TOC-250417&sap-outbound-id=8E718931F683E1059908352664B7F7F69DE5047E&utm_source=standard&utm_medium=email&utm_campaign=000_SKN6563_0000039309_41586-Nature-20250417-EAlert&utm_content=EN_73816_20250417&mkt-key=9DF045C0F2C81EDFA481C56E6871B8B4] emerges(Nature) * Whooping cough spikes, especially among unvaccinated teens [https://www.nbcnews.com/health/health-news/whooping-cough-spike-unvaccinated-teens-rcna171781] (NBC News) * A February flu surge [https://www.nbcnews.com/health/health-news/flu-cases-high-cdc-illness-hospitalizations-rcna191203] has arrived (NCB News) * Pertussis Cases [https://www.cdc.gov/pertussis/php/surveillance/pertussis-cases-by-year.html] by Year (1922-2022)(CDC: Whooping cough (pertussis))) * ‘Fighting to breathe’ [https://www.nbcnews.com/health/health-news/whooping-cough-surges-vaccines-decline-us-rcna201853]: Whooping cough surges as vaccination rate falters (NBC News) * CDC cancels measles [https://www.healthday.com/health-news/infectious-disease/cdc-cancels-measles-help-for-texas-schools-amid-staff-layoffs] help for Texas schools amid staff layoffs (HealthDay) * Measles cases and outbreaks [https://www.cdc.gov/measles/data-research/index.html] (CDC Rubeola) * Measles in Texas [https://www.dshs.texas.gov/news-alerts/measles-outbreak-2025]…. (Texas Health and Human Services) * Measles vaccine recommendations from NYP (jpg [https://www.microbe.tv/twiv/wp-content/uploads/sites/2/measles_vax_rec_2.png])  * 2025 Measles outbreak guidance [https://www.nmhealth.org/about/erd/ideb/mog/] (New Mexico Health) * Get the FACTS [https://www.health.ny.gov/diseases/communicable/measles/] about measles (NY State Department of Health) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] vaccine (CDC Measles (Rubeola)) * Presumptive evidence [file:///Users/Amy/Desktop/Measles%20(CDC%20Measles%20(Rubeola))] of measles immunity (CDC) * Contraindications and precautions [https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-13-measles.html#cdc_report_pub_study_section_9-contraindications-and-precautions-to-vaccination] to measles vaccination (CDC) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] (CDC: Measles Rubeola) * Adverse events associated with childhood vaccines [https://www.ncbi.nlm.nih.gov/books/NBK236284/#:~:text=The%20evidence%20favors%20acceptance%20of,in%20temporal%20relation%20to%20vaccination]: evidence bearing on causality (NLM) * Measles Vaccination: [https://www.idsociety.org/public-health/measles/know-the-facts/] Know the Facts(ISDA: Infectious Diseases Society of America) * Deaths following vaccination: what does the evidence show [https://www.sciencedirect.com/science/article/abs/pii/S0264410X15006556?via%3Dihub] (Vaccine) * RFK Jr.’s autism registry [https://www.axios.com/2025/04/23/autism-registry-rfk-nih] plan (Axios) * RFK Jr’s autism study collecting Americans’ private medical [https://www.theguardian.com/us-news/2025/apr/22/rfk-jr-autism-nih] records (Guardian) * The public’s views on measles outbreaks and misinformation [https://www.kff.org/health-information-and-trust/poll-finding/kff-tracking-poll-on-health-information-and-trust-the-publics-views-on-measles-outbreaks-and-misinformation/] (KFF) *  Colombia National Emergency: yellow fever cases [https://www.minsalud.gov.co/CC/Noticias/2025/Paginas/emergencia-sanitaria-en-todo-el-territorio-nacional-por-aumento-en-los-casos-de-fiebre-amarilla.aspx] (Gov.Co) * World Immunization Week [https://polioeradication.org/news/rise-together-to-end-polio-uk-public-called-to-join-mass-movement-challenge-with-strava/]: polio eradiation?(GPEI) * Influenza: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * Respiratory virus activity [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] levels (CDC Respiratory Illnesses) * 200 children [https://www.cidrap.umn.edu/us-flu-levels-drop-below-baseline-kids-deaths-approach-200] die from flu (CIDRAP) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * FDA-CDC-DOD: [https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2026-us-influenza-season?mtm_source=25] 2025-2046 influenza vaccine composition (FDA) * RSV: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * RSV-Net [https://www.cdc.gov/rsv/php/surveillance/rsv-net.html]work (CDC Respiratory Syncytial virus Infection) * Trial shows waning efficacy [https://www.cidrap.umn.edu/respiratory-syncytial-virus-rsv/trial-shows-waning-efficacy-rsv-vaccine-across-3-seasons-older] of RSV vaccine across 3 seasons in older adults(CIDRAP) * Efficacy, safety, and immunogenicity [https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00048-7/abstract] of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) (LANCET: Respiratory Medicine) * Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * COVID-19 deaths [https://covid.cdc.gov/covid-data-tracker/#maps_percent-covid-deaths] (CDC) * COVID-19 national and regional [https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html] trends (CDC) * COVID-19 variant tracker [https://covid.cdc.gov/covid-data-tracker/index.html#variant-proportions] (CDC) * SARS-CoV-2 genomes [https://nextstrain.org/ncov/gisaid/global/all-time?d=tree,frequencies&p=full&r=division&showBranchLabels=all&tl=none] galore (Nextstrain) * Where [https://www.pemgarda.com/hcp/infusion-center-locator/] to get pemgarda (Pemgarda) * EUA [https://investors.adagiotx.com/news-releases/news-release-details/invivyd-announces-fda-authorization-emergency-use-pemgardatm] for the pre-exposure prophylaxis of COVID-19 (INVIYD) * Infusion center [https://primeinfusions.com/locations/] (Prime Fusions) * CDC Quarantine [https://www.cdc.gov/respiratory-viruses/guidance/faqs.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/guidance/faq.html] guidelines (CDC) * NIH [https://www.ncbi.nlm.nih.gov/books/NBK570371/] COVID-19 treatment guidelines (NIH) * Drug interaction checker [https://covid19-druginteractions.org/checker] (University of Liverpool) * Long-term stroke and mortality risk reduction [https://onlinelibrary.wiley.com/doi/10.1002/jmv.70351] associated with acute-phase paxlovid use in mild-to-moderate COVID-19(Journal of Medical Virology) * Infectious Disease Society guidelines [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground] for treatment and management (ID Society) * Molnupiravir safety [https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011] and efficacy (JMV) * Convalescent plasma recommendation for immunocompromised [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/] (ID Society) * What to do when sick with a respiratory virus [https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html] (CDC) * When your healthcare provider is infected/exposed [https://www.cdc.gov/covid/hcp/infection-control/guidance-risk-assesment-hcp.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-assesment-hcp.html] with SARS-CoV-2 (CDC) * Managing healthcare staffing shortages [https://www.cdc.gov/covid/hcp/infection-control/mitigating-staff-shortages.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html] (CDC) * Steroids, dexamethasone [https://academic.oup.com/ofid/article/10/3/ofad105/7055978] at the right time (OFID) * Anticoagulation [https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19] guidelines (hematology.org) * Daniel Griffin’s evidence based [https://academic.oup.com/ofid/article/11/9/ofae462/7733485] medical practices for long COVID (OFID) * Long COVID hotline [https://www.columbiadoctors.org/health-library/article/long-covid/] (Columbia : Columbia University Irving Medical Center) * The answers: [https://longcovidtheanswers.com/] Long COVID * The effect of COVID-19 vaccination [https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiaf133/8071565#google_vignette] on the risk of persistent post–COVID-19 condition (JID) * ORCHESTRA [https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(25)00172-7/fulltext?dgcid=raven_jbs_aip_email] Delphi consensus: diagnostic and therapeutic management of Post-COVID-19 condition in vulnerable populations (CMI Clinical Microbiology and Infection) * Political ideology and trust in scientists [https://www.nature.com/articles/s41562-025-02147-z] in the USA(Nature Human Behavior) * Leading long COVID researcher fears it could become [https://ny1.com/nyc/all-boroughs/news/2025/04/16/leading-long-covid-researcher-fears-it-could-become-national-epidemic] a national epidemic (Spectrum News NY1) * Center for post COVID [https://www.mountsinai.org/about/covid19/center-post-covid-care] care (Mt. Sinai) Reaching out to US house representative [https://www.house.gov/representatives/find-your-representative] * Letters read [https://www.microbe.tv/twiv/twiv-1212-letters/] on TWiV 1212 * Dr. Griffin’s COVID treatment summary (pdf [https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf]) * Timestamps by Jolene Ramsey [https://ramseylab.vercel.app/]. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Stephan Urban about his career working on HBV and HDV, and his philanthropy. Host: Rich Condit [https://mgm.ufl.edu/profile/condit-rich/] Guest: Stephan Urban [https://molbio.princeton.edu/speakers/stephan-urban-phd] Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Support science education  [http://www.microbe.tv/contribute]at MicrobeTV * ASV 2025 [http://asv.org/asv2025] * Hepatitis delta [https://pubmed.ncbi.nlm.nih.gov/36738087/]: recent advances (Hepatology) * Bulevirtide for HBV and HDV [https://pubmed.ncbi.nlm.nih.gov/36113537/] (Lancet Inf Dis) * Timestamps by Jolene [https://ramseylab.vercel.app/] Ramsey. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV discusses the rising autism rate among children, RFK Jr.’s claim that autism ‘destroys lives’, receptor binding specificity of a bovine H5N1 influenza virus, and improved dengue subunit vaccine modified to form E protein dimers. Hosts: Vincent Racaniello [https://en.wikipedia.org/wiki/Vincent_Racaniello], Alan Dove [http://www.turbidplaque.com/], Rich Condit [https://mgm.ufl.edu/profile/condit-rich/], and Brianne Barker [https://bsky.app/profile/bioprofbarker.bsky.social] Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Support science education  [http://www.microbe.tv/contribute]at MicrobeTV * ASV 2025 [http://asv.org/asv2025] * Rising autism rate [https://www.nytimes.com/2025/04/15/health/autism-children-cdc.html] among children (MMWR) * RFK Jr. claims autism ‘destroys lives [https://www.nytimes.com/2025/04/18/well/autism-kennedy-reaction.html]‘ (NY Times) * Receptor binding specificity [https://www.nature.com/articles/s41586-025-08822-5] of bovine H5N1 virus (Nature) * Bovine H5N1 binds poorly to human receptors (Nature) * AJ Eisfeld [https://pubmed.ncbi.nlm.nih.gov/40240851/] et al reply (Nature) * Mootant influenza H5N1 virus (TWiV 1131 [https://www.microbe.tv/twiv/twiv-1131/]) * Improved dengue 2 subunit vaccine [https://journals.asm.org/doi/full/10.1128/jvi.00229-25?af=R] (J Virol) * Letters read [https://www.microbe.tv/twiv/twiv-1211-letters/] on TWiV 1211 * Timestamps by Jolene [https://ramseylab.vercel.app/] Ramsey. Thanks! Weekly Picks Brianne – Scientists detect signature of life on a distant planet, study suggests [https://www.cnn.com/2025/04/17/science/k218b-potential-biosignature-webb/index.html] Rich – Hanlon’s Razor [https://en.wikipedia.org/wiki/Hanlon%27s_razor] Alan – Baby colossal squid filmed in deep ocean [https://www.science.org/content/article/colossal-squid-filmed-its-natural-habitat-first-time] Vincent –  [https://www.nature.com/articles/d41586-025-01108-w]How the United States became a science superpower — and how quickly it could crumble [https://www.nature.com/articles/d41586-025-01146-4] Listener Pick John – Revisionist History: The RFK Jr. Problem [https://www.pushkin.fm/podcasts/revisionist-history/the-rfk-jr-problem] Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment. Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Making America Healthy Again-purging [https://www.politico.com/news/2025/04/04/confusion-and-despair-as-health-agency-workers-tally-their-losses-00272639] of administrators at HHS (Politico) * Making America Healthy Again-purging of data [https://www.politico.com/news/2025/04/13/abortions-cancer-in-firefighters-and-super-gonorrhea-rfk-jr-s-cuts-halt-data-collection-00284828] (Politico) * Deep cuts [https://www.nytimes.com/interactive/2025/03/28/us/politics/trump-doge-federal-job-cuts.html] of the federal government (NY Times) * Cutting NIH, CDC and HHS [https://docs.google.com/document/d/1yXjGhPW7ebmq-a661yaivt-HKGc9uhFKNCAgwQmxDTU/edit?tab=t.0] promotes chronic disease research(Washington Post) * Political ideology and trust in scientists [https://www.nature.com/articles/s41562-025-02147-z] in the USA(Nature Human Behavior) * US political conservatives have deep, unbudging suspicion of science, survey suggests(CIDRAP) * A deadly E. coli outbreak hit 15 states, but the FDA chose not [https://www.nbcnews.com/news/us-news/ecoli-bacteria-lettuce-outbreak-rcna200236] to publicize it(NBC News) * Invasive meningococcal disease [https://www.who.int/emergencies/disease-outbreak-news/item/2025-DON563?mtm_source=25] – Kingdom of Saudi Arabia(WHO) * The essential guide to understanding the differences between hajj and umrah [https://marhabahaji.com/blog-post/differences-between-hajj-and-umrah#:~:text=Hajj%20and%20Umrah%20are%20two%20of%20the%20most%20important%20pilgrimage,be%20performed%20at%20any%20time] (Marhabahaji) * Measles Vaccination: [https://www.idsociety.org/public-health/measles/know-the-facts/] Know the Facts(ISDA: Infectious Diseases Society of America) * Measles booster [https://www.washingtonpost.com/wellness/2025/03/24/measles-vaccine-booster-outbreak-states/]? (Washington Post) * How to stop an outbreak…….fire the experts [https://www.washingtonpost.com/health/2025/04/16/texas-measles-response-funding-cuts/] (Washington Post) * Measles cases and outbreaks [https://www.cdc.gov/measles/data-research/index.html] (CDC Rubeola) * Measles 159 in Texas [https://www.dshs.texas.gov/news-alerts/measles-outbreak-2025]…. (Texas Health and Human Services) * 2025 Measles outbreak guidance [https://www.nmhealth.org/about/erd/ideb/mog/] (New Mexico Health) * Measles and rubella [https://health-infobase.canada.ca/measles-rubella/] weekly monitoring (Government of Canada) * Measles vaccine recommendations from NYP (jpg [https://www.microbe.tv/twiv/wp-content/uploads/sites/2/measles_vax_rec_2.png]) * NAFMA: North American Free Measles [https://www.nytimes.com/2025/04/17/health/measles-texas-mexico-canada.html#:~:text=Canada%20has%20reported%20more%20than,according%20to%20Mexican%20health%20authorities] agreement…..(NY Times) * Get the FACTS [https://www.health.ny.gov/diseases/communicable/measles/] about measles (NY State Department of Health) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] vaccine (CDC Measles (Rubeola)) * Presumptive evidence [file:///Users/Amy/Desktop/Measles%20(CDC%20Measles%20(Rubeola))] of measles immunity (CDC) * Contraindications and precautions [https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-13-measles.html#cdc_report_pub_study_section_9-contraindications-and-precautions-to-vaccination] to measles vaccination (CDC) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Doctors’ talk measles [https://www.youtube.com/watch?v=-16RnFwe0jc] (YouTube) * Measles [https://www.cdc.gov/measles/index.html] (CDC: Measles Rubeola) * Adverse events associated with childhood vaccines [https://www.ncbi.nlm.nih.gov/books/NBK236284/#:~:text=The%20evidence%20favors%20acceptance%20of,in%20temporal%20relation%20to%20vaccination]: evidence bearing on causality (NLM) * Measles Vaccination: [https://www.idsociety.org/public-health/measles/know-the-facts/] Know the Facts(ISDA: Infectious Diseases Society of America) * Deaths following vaccination: what does the evidence show [https://www.sciencedirect.com/science/article/abs/pii/S0264410X15006556?via%3Dihub] (Vaccine) * Influenza: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * Respiratory virus activity [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] levels (CDC Respiratory Illnesses) * 200 children [https://www.cidrap.umn.edu/us-flu-levels-drop-below-baseline-kids-deaths-approach-200] die from flu (CIDRAP) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * FDA-CDC-DOD: [https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2026-us-influenza-season?mtm_source=25] 2025-2046 influenza vaccine composition (FDA) * RSV: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * RSV-Net [https://www.cdc.gov/rsv/php/surveillance/rsv-net.html]work (CDC Respiratory Syncytial virus Infection) * ACIP votes to expand recommendation [https://www.pfizer.com/news/press-release/press-release-detail/acip-votes-expand-recommendation-pfizers-rsv-vaccine?cid=em_PfizerNewsroomAlert&ttype=em] for Pfizer’sRSV vaccine Abrysvo® to include adults aged 50 to 59 at increased risk of disease (Pfizer) * Respiratory syncytial virus and incidence of cardiovascular events [https://www.jacc.org/doi/abs/10.1016/j.jacc.2025.02.031]: a nationwide self-controlled case series analysis (JACC Journals) * Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * COVID-19 deaths [https://covid.cdc.gov/covid-data-tracker/#maps_percent-covid-deaths] (CDC) * COVID-19 national and regional [https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html] trends (CDC) * COVID-19 variant tracker [https://covid.cdc.gov/covid-data-tracker/index.html#variant-proportions] (CDC) * SARS-CoV-2 genomes [https://nextstrain.org/ncov/gisaid/global/all-time?d=tree,frequencies&p=full&r=division&showBranchLabels=all&tl=none] galore (Nextstrain) * Comorbidities associated with different degrees of severity in children and young people [https://journals.lww.com/pidj/abstract/2025/05000/comorbidities_associated_with_different_degrees_of.13.aspx] hospitalized with acute COVID-19 (Pediatric Infectious Disease Journal) * SHIELD-Utah study shows Novavax’s COVID-19 vaccine [https://ir.novavax.com/press-releases/2025-04-15-SHIELD-Utah-Study-Shows-Novavaxs-COVID-19-Vaccine-Induces-Lower-Reactogenicity-Symptoms-Compared-to-mRNA] induces lower reactogenicity symptoms compared to mRNA (Novavax) * Interim clinical considerations for use of COVID-19 vaccines [https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html] in the United States (CDC Vaccines & Immunizations) * Novavax says its COVID vaccine produces fewer, milder reactions [https://www.cidrap.umn.edu/covid-19/novavax-says-its-covid-vaccine-produces-fewer-milder-reactions-pfizer-version] than Pfizer version(CIDRAP) * US CDC advisers discuss narrower use [https://www.reuters.com/business/healthcare-pharmaceuticals/us-cdc-advisers-review-vaccine-guidelines-after-months-long-delay-2025-04-15/] of COVID-19 vaccines (Reuters) * Where [https://www.pemgarda.com/hcp/infusion-center-locator/] to get pemgarda (Pemgarda) * EUA [https://investors.adagiotx.com/news-releases/news-release-details/invivyd-announces-fda-authorization-emergency-use-pemgardatm] for the pre-exposure prophylaxis of COVID-19 (INVIYD) * Infusions center [https://primeinfusions.com/locations/] (Prime Fusions) * CDC Quarantine [https://www.cdc.gov/respiratory-viruses/guidance/faqs.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/guidance/faq.html] guidelines (CDC) * NIH [https://www.ncbi.nlm.nih.gov/books/NBK570371/] COVID-19 treatment guidelines (NIH) * Drug interaction checker [https://covid19-druginteractions.org/checker] (University of Liverpool) * Infectious Disease Society guidelines [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground] for treatment and management (ID Society) * Molnupiravir safety [https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011] and efficacy (JMV) * Convalescent plasma recommendation for immunocompromised [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/] (ID Society) * What to do when sick with a respiratory virus [https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html] (CDC) * When your healthcare provider is infected/exposed [https://www.cdc.gov/covid/hcp/infection-control/guidance-risk-assesment-hcp.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-assesment-hcp.html] with SARS-CoV-2 (CDC) * Managing healthcare staffing shortages [https://www.cdc.gov/covid/hcp/infection-control/mitigating-staff-shortages.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html] (CDC) * Steroids, dexamethasone [https://academic.oup.com/ofid/article/10/3/ofad105/7055978] at the right time (OFID) * Anticoagulation [https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19] guidelines (hematology.org) * Daniel Griffin’s evidence based [https://academic.oup.com/ofid/article/11/9/ofae462/7733485] medical practices for long COVID (OFID) * Long COVID hotline [https://www.columbiadoctors.org/health-library/article/long-covid/] (Columbia : Columbia University Irving Medical Center) * The answers: [https://longcovidtheanswers.com/] Long COVID * Kidney Function [https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2832549?guestAccessKey=40fa9bc5-7dcf-4407-94a9-0379466f0097&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041125] following COVID-19 in children and adolescents(JAMA Network Open) * Cardiovascular post-acute sequelae [https://www.nature.com/articles/s41467-025-56284-0] of SARS-CoV-2 in children and adolescents: cohort study using electronic health records(Nature Communications) * Great barrington declaration [https://gbdeclaration.org/] (gbdeclaration.org) * Clinical trials: * Effectiveness of transcranial direct current [https://clinicaltrials.gov/study/NCT05780450] in patients with persistent COVID-19 with headaches and chronic pain. * Home-based Brain Stimulation Treatment [https://clinicaltrials.gov/study/NCT05092516] for Post-acute Sequelae of COVID-19 (PASC) * Acupuncture for post COVID-19 Condition (Long COVID) neuropsychiatric symptoms [https://clinicaltrials.gov/study/NCT06633666] * Pain relief with integrative medicine (prime)?: feasibility of acupuncture [https://clinicaltrials.gov/study/NCT06476496] for long COVID * Electro-acupuncture [https://clinicaltrials.gov/study/NCT05890508] for long COVID neuropsychiatric symptoms * Randomised study to investigate the effectiveness of acupuncture for the relief of long COIVD-19 related fatigue (ACU-COVID) [https://clinicaltrials.gov/study/NCT05212688] * Vagus stimulation in female long COVID patients.(Vagus [https://clinicaltrials.gov/study/NCT05918965]) * Stellate ganglion block with lidocaine for the treatment of COVID-19-induced parosmia (Stella [https://clinicaltrials.gov/study/NCT06055270]) * Therapeutic updates on long COVID: Where things stand 5 years later [https://www.idsociety.org/science-speaks-blog/2025/therapeutic-updates-on-long-covid-where-things-stand-5-years-later/#/+/0/publishedDate_na_dt/desc/] (ID Society) * Reaching out to US house representative [https://www.house.gov/representatives/find-your-representative] * Letters read [https://www.microbe.tv/twiv/twiv-1210-letters/] on TWiV 1210 * Dr. Griffin’s COVID treatment summary (pdf [https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf]) * Timestamps by Jolene Ramsey [https://ramseylab.vercel.app/]. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.