Bioprocessing Unfiltered

Episode: 4 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations - Part 1

23 min · 6 jan 2026
aflevering Episode: 4 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations - Part 1 artwork

Beschrijving

How can we optimize manufacturing and operations? In this episode of Bioprocessing Unfiltered, Andrew Sinclair, president and founder of Biopharm Services, provides insight from his 35-year-long career in the industry on the most significant ways data management and predictive modeling can improve efficiency during the manufacturing process. With host William Whitford, founder of Oamaru BioSystems, Sinclair delves into the history and impact of costs, how to handle evolving efficiencies, and why understanding definitions can be useful for speaking the language of regulators and rating organizations. Links from this episode: Bioprocessing Summit [https://www.bioprocessingsummit.com/] Biopharm Services [https://biopharmservices.com/]  Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

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Alle afleveringen

8 afleveringen

aflevering Episode: 8 - Jack Prior of Sanofi on AI Readiness in Biomanufacturing artwork

Episode: 8 - Jack Prior of Sanofi on AI Readiness in Biomanufacturing

In this episode of Bioprocessing Unfiltered, Jack Prior, head of process monitoring and data science and AI strategy at Sanofi, explores how AI has evolved from early expert systems to machine learning, generative AI, and agentic AI, and what that means for biomanufacturing today. He explains why digital transformation has not automatically created usable data, and why the real challenge is turning fragmented information from manufacturing systems into accessible, authentic, and analysis-ready data. Jack shares a practical framework for assessing data maturity and argues that the biggest near-term opportunity for AI is reducing friction in data engineering, troubleshooting, tech transfer, and decision support across bioprocessing organizations.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]  Sanofi [https://www.sanofi.com/en]      Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

5 mei 202639 min
aflevering Episode: 7 - Anurag Rathore on Platform Processes, Chromatography, and Expanding Education artwork

Episode: 7 - Anurag Rathore on Platform Processes, Chromatography, and Expanding Education

Anurag Rathore, professor of chemical engineering at the Indian Institute of Technology Delhi, joins Bioprocessing Unfiltered with host Alois Jungbauer to discuss his long career in advancing bioprocessing engineering. Rathore shares his thoughts on chromatography, using platform processes to accelerate process development, how infinity capture can be a way to arrive at platform processes, and if there is a need for alternative methods. He also explores updates needed to the traditional curriculum of biochemical engineering—and if the next generation should know how to use AI and ML—and his view on bioprocess and development.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]  Indian Institute of Technology Delhi [https://home.iitd.ac.in/]  Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

8 apr 202632 min
aflevering Episode: 6 - Fireside Chat: Innovation and Investment in Biomanufacturing of Future Medicine artwork

Episode: 6 - Fireside Chat: Innovation and Investment in Biomanufacturing of Future Medicine

At the most recent Bioprocessing Summit, David Y. H. Chang, CEO of Taiwan Bio-Manufacturing Company; Bo Wiinberg, Chief Business Development Officer of Novo Nordisk Foundation Cellerator; and Paul Lewus, Vice President of Site Operations at Amgen gathered for a fireside chat moderated by Ran Zheng, former CEO of Landmark Bio, to discuss the technologies and innovations shaping the future of biomanufacturing. The conversation explored upcoming trends, investment opportunities, and modalities into the next decade, as well as the question: how should the industry best prepare for all of it?  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/] Landmark Bio [https://landmarkbio.com/] Novo Nordisk Foundation Cellerator [https://novonordiskfonden.dk/en/projects/novo-nordisk-foundation-cellerator/] Taiwan Bio-Manufacturing Company (TBMC) [https://tbmcbio.com/] Amgen [https://www.amgen.com/]    Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

10 mrt 202655 min
aflevering Episode: 5 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations, Part 2 artwork

Episode: 5 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations, Part 2

Picking up from their previous conversation on Bioprocessing Unfiltered, Andrew Sinclair, president and founder of BioPharm Services Ltd., and host William Whitford, founder of Oamaru BioSystems, discuss improving manufacturing efficiency, including process mass intensity and setting up parameters, and more on Sinclair’s long career and valuable experiences in the industry. Sinclair also shares advice on helping someone who cannot meet parameters, how to navigate new profusions, and default values that can help others with their processes.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]   Biopharm Services [https://biopharmservices.com/]    Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

3 feb 202635 min
aflevering Episode: 4 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations - Part 1 artwork

Episode: 4 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations - Part 1

How can we optimize manufacturing and operations? In this episode of Bioprocessing Unfiltered, Andrew Sinclair, president and founder of Biopharm Services, provides insight from his 35-year-long career in the industry on the most significant ways data management and predictive modeling can improve efficiency during the manufacturing process. With host William Whitford, founder of Oamaru BioSystems, Sinclair delves into the history and impact of costs, how to handle evolving efficiencies, and why understanding definitions can be useful for speaking the language of regulators and rating organizations. Links from this episode: Bioprocessing Summit [https://www.bioprocessingsummit.com/] Biopharm Services [https://biopharmservices.com/]  Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

6 jan 202623 min