Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO with Paul Garofolo

From Startup to Global CRO: Joe von Rickenbach on Building Parexel and Transforming Clinical Research

In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Joe von Rickenbach, co-founder of Parexel and a pioneer of the modern clinical research organization (CRO) industry, to discuss his journey from launching a two-person regulatory consulting firm in 1982 to building a global CRO that helped redefine drug development worldwide. Joe reflects on the evolution of clinical trials, the rise of outsourcing and digitization in pharma, and the leadership lessons learned from scaling Parexel over 35 years. He also shares insights on entrepreneurship, navigating major business decisions and the future of AI-enabled clinical research, and why trust, relationships, and adaptability remain essential for success in biotech and healthcare innovation. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

From Legal to Leadership: Becoming a Successful Biotech CEO with Heather Turner

How do you go from lawyer to biotech CEO? In this episode of Clinical Trialblazers, Heather Turner, CEO of LB Pharmaceuticals, shares her journey from legal counsel to leading a late-stage biotech company. She discusses the mindset shifts required to step into the CEO role, making high-stakes decisions with incomplete data, and balancing risk versus benefit. Heather brings more than 25 years of experience across biotech and life sciences, with a career that uniquely spans legal, operational, and executive leadership. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

From Physician to Biotech CEO: Building High-Impact Clinical Development with Dr. Allison Jeynes

In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Dr. Allison Jeynes, CEO of Nefro Avillion Clinical Development, to explore her remarkable journey from clinician to biotech leader. With over 30 years of experience and a track record that includes the development and approval of nearly 20 drugs, Allison shares how she built a 100% success-rate model in clinical development, and what it takes to sustain excellence in a high-risk industry. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO with Paul Garofolo

Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

Season 2 is Coming Soon

Clinical Trialblazers will be back soon! Season 2 will bring together a dynamic mix of biotech innovators, executives, and industry leaders to reveal the strategy and teamwork fueling the next wave of clinical breakthroughs. Across 10 new episodes, host Alberto Grignolo will explore high-stakes decisions, unexpected hurdles, and the defining moments that shape both careers and clinical milestones. Season 2 of Clinical Trialblazers is streaming soon wherever you listen to podcasts. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.