Health Policy Podcast

The $100 Billion Loophole: Why 340B Reform is Essential

17 min · 30. juni 2026
episode The $100 Billion Loophole: Why 340B Reform is Essential cover

Description

Economist Wayne Winegarden joins the podcast to expose how the 340B Drug Discount Program evolved from a small safety net for rural clinics into a \$100 billion revenue engine for massive hospital systems. He explores how misaligned incentives drive up drug spending, fuel hospital consolidation, and why transparency is the first step toward reform.

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26 episodes

episode The Human and Economic Toll of Treatment-Resistant Depression artwork

The Human and Economic Toll of Treatment-Resistant Depression

Treatment-resistant depression (TRD) affects millions of Americans and carries significant personal, clinical, and economic consequences. In this episode of the Health Policy Podcast, host Bryan Hyde speaks with Dr. William Sauvé, Chief Medical Officer of Osmind, and Mark Desmarais, Principal at Health Management Associates, about new research examining the impact of TRD on patients and the healthcare system. Drawing on a comprehensive analysis of Medicare claims data, Desmarais explains how patients with TRD generate approximately $8,000 more in annual healthcare costs than patients whose depression is effectively managed. The discussion explores the reasons behind these costs, including higher rates of physician visits and hospitalizations, as well as their impact on both individuals and caregivers. Dr. Sauvé, a psychiatrist with extensive experience treating complex depression cases in both military and civilian settings, discusses TRD, the challenges patients face after multiple unsuccessful medication trials, and the importance of identifying effective treatments. The conversation also examines workforce shortages in mental health care, barriers posed by prior authorization requirements, and how delaying effective treatment can worsen patient outcomes and increase healthcare spending.

23. juni 202620 min