The Natural GLP-1 Alternative

The Natural GLP-1 Alternative

In this episode of Hormone Heroines, we sit down with Sarah Kennedy, founder and CEO of Calocurb, to explore the science behind natural GLP-1 activation and appetite regulation. Sarah explains how our bodies naturally produce GLP-1 and other appetite-regulating hormones after eating, why these signals can become less effective with age and modern eating habits, and how prescription GLP-1 medications differ from the body's normal physiology. We discuss how Calocurb was developed through more than 16 years of New Zealand government-funded research and uses a proprietary bitter hop extract to stimulate bitter taste receptors in the intestines, encouraging the body's own release of GLP-1, CCK, and PYY. Sarah reviews the early clinical research showing increased appetite-regulating hormone release and reduced calorie intake, as well as an upcoming larger clinical trial evaluating weight loss and body composition that had not yet been published at the time of this interview. The conversation also explores how clinicians are using Calocurb for individuals seeking a natural option, those unable to tolerate GLP-1 medications, and patients transitioning off prescription GLP-1 therapy. Throughout the episode, Sarah and the hosts emphasize that appetite support works best when combined with healthy nutrition, regular movement, and sustainable lifestyle changes. - - - - - About the Guest: Sarah Kennedy is the founder and CEO of Calocurb, a New Zealand company focused on developing evidence-based, plant-derived solutions for appetite regulation and weight management. Working alongside research supported by the New Zealand government, Sarah has helped commercialize Calocurb after more than 16 years of scientific development. She is passionate about translating nutritional science into practical tools that support healthy weight management through the body's natural appetite-regulating mechanisms. - - - - - 10% off discount code: BLOSS10 https://www.calocurb.com/BlossLong [https://www.google.com/url?q=https://www.calocurb.com/BlossLong&sa=D&source=editors&ust=1784066120116374&usg=AOvVaw0zQKKiR5PP5BrJ43bBY-_9] Calocurb is a clinically proven, plant-based nutraceutical that reduces hunger by 30%, cravings by 40% and calorie intake by 18%. All natural, Calocurb contains no stimulants, nothing synthetic and is caffeine-free, vegan and certified non-GMO. The active ingredient in Calocurb is a unique extract from the hops flower developed and clinically tested by leading New Zealand scientists from Plant & Food Research over 14 years and with $30m investment. Calocurb gets to work in just one hour so you can feel full faster. - - - - - The Hormone Heroines Instagram: https://www.instagram.com/hormone_heroines/ [https://www.instagram.com/hormone_heroines/] Spotify: https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb [https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb] Apple Podcast: https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060 [https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060] iHeart Radio: https://iheart.com/podcast/305165609/ [https://iheart.com/podcast/305165609/] Shop Supplements: https://partnerships.timeline.com/BLOSSOMINGLONGEVITY [https://partnerships.timeline.com/BLOSSOMINGLONGEVITY] - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/ [https://drtalks.com/podcast-service/]

Vaginal Health Deep Dive

In this episode of Hormone Heroines, we sit down with Dr. Christina Enzmann, board-certified OB-GYN and menopause specialist, to discuss genitourinary syndrome of menopause (GSM)—a commonly overlooked group of vaginal, urinary, and sexual-health symptoms linked to declining estrogen. Dr. Enzmann explains why GSM is much more than vaginal dryness. Symptoms can include painful sex, vaginal burning or irritation, urinary urgency, frequent urination, recurrent bladder infections, and UTI-like symptoms that do not always show up on standard testing. We discuss why these symptoms may begin during perimenopause rather than only after menopause, as well as why they may also occur postpartum during breastfeeding or in some younger women using hormonal birth control. Throughout the conversation, we explore the role of estrogen in maintaining vaginal tissue, inflammation control, healing, pH balance, and the vaginal microbiome. Dr. Enzmann shares her clinical approach to local vaginal estrogen, vaginal DHEA, treatment for BV and recurrent yeast, and strategies for avoiding unnecessary antibiotic use that can further disrupt the vaginal, bladder, and gut microbiomes. We also discuss sexual comfort, lubricants, vaginal moisture, recurrent irritation, and emerging therapies such as vaginal red-light devices. This episode is an important conversation for anyone experiencing vaginal or urinary symptoms during perimenopause, menopause, postpartum, or other hormonal transitions. - - - - - About the Guest: Dr. Christina Enzmann is a board-certified obstetrician and gynecologist, menopause specialist, and functional medicine practitioner. Originally from Germany, she has practiced in the United States for more than 20 years and combines conventional gynecology with a functional-medicine approach to support women through perimenopause, menopause, vaginal health concerns, urinary symptoms, and complex hormonal transitions. Dr. Enzmann is passionate about helping women understand the often-overlooked effects of estrogen changes on the vagina, bladder, microbiome, metabolism, and overall quality of life. Website: https://drchristinaenzmann.com/ [https://drchristinaenzmann.com/] LinkedIn: https://www.linkedin.com/in/dr-christina-c-enzmann-2a794810/ [https://www.linkedin.com/in/dr-christina-c-enzmann-2a794810/] - - - - - Hormone Heroines Instagram: https://www.instagram.com/hormone_heroines/ [https://www.instagram.com/hormone_heroines/] Spotify: https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb [https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb] Apple Podcast: https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060 [https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060] iHeart Radio: https://iheart.com/podcast/305165609/ [https://iheart.com/podcast/305165609/] Shop Supplements: https://partnerships.timeline.com/BLOSSOMINGLONGEVITY [https://partnerships.timeline.com/BLOSSOMINGLONGEVITY] - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/ [https://drtalks.com/podcast-service/]

Burning Mouth Syndrome: Why Women Are Dismissed & What May Actually Help

In this episode of Hormone Heroines, we sit down with Dr. Susan Sklar, physician and founder of Hope for Burning Mouth, to discuss Burning Mouth Syndrome (BMS), a chronic neuropathic pain condition that disproportionately affects perimenopausal and menopausal women. Dr. Sklar explains what Burning Mouth Syndrome feels like, why diagnosis can take years, and how many women are often dismissed or told their symptoms are psychological despite experiencing significant chronic pain. We discuss the challenges patients face navigating the healthcare system and the emotional toll that chronic pain can have on daily life. Throughout the conversation, Dr. Sklar shares her clinical approach to treating Burning Mouth Syndrome, including the role of hormone replacement therapy, thyroid health, vitamin D, nutritional deficiencies, stress management, and low-dose naltrexone. She explains how hormones may influence pain pathways, inflammation, and nerve function, and why addressing underlying physiological imbalances may be an important part of treatment. - - - - - About the Guest: Dr. Susan Sklar is a Harvard-trained physician with more than 40 years of clinical experience. After practicing obstetrics and gynecology for 25 years, she transitioned into restorative and longevity medicine, where she became deeply involved in helping patients suffering from Burning Mouth Syndrome. Through her work with Hope for Burning Mouth, Dr. Sklar focuses on identifying underlying hormonal, nutritional, and neurological factors that may contribute to chronic neuropathic pain. She is passionate about educating patients and practitioners about the connection between hormones, chronic pain, and women's health. Website: www.susansklarmd.com [https://susansklarmd.com/] Hope for Burning Mouth: https://susansklarmd.com/hope-burning-mouth/ [https://susansklarmd.com/hope-burning-mouth/] Get the Kindle Book on Amazon: https://susansklarmd.com/burning-mouth-book/ [https://susansklarmd.com/burning-mouth-book/] Get BMS Coaching Today: https://susansklarmd.com/bms-coaching/ [https://susansklarmd.com/bms-coaching/] - - - - - Hormone Heroines Instagram: https://www.instagram.com/hormone_heroines/ [https://www.instagram.com/hormone_heroines/] Spotify: https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb [https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb] Apple Podcast: https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060 [https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060] iHeart Radio: https://iheart.com/podcast/305165609/ [https://iheart.com/podcast/305165609/] Shop Supplements: https://partnerships.timeline.com/BLOSSOMINGLONGEVITY [https://partnerships.timeline.com/BLOSSOMINGLONGEVITY] - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/ [https://drtalks.com/podcast-service/]

Fasting for Longevity? The Science Behind Fasting-Mimicking Diets & Healthy Aging

In this episode of Hormone Heroines, we sit down with Renee Fitton, registered dietitian, longevity nutrition expert, and Vice President of Education and Growth at Prolon, to explore the science of fasting-mimicking diets and their potential role in healthy aging. Renee explains how fasting-mimicking diets are designed to recreate many of the biological effects of prolonged fasting while still allowing individuals to consume specially formulated foods. We discuss how nutrient-sensing pathways influence cellular repair processes and why fasting has become a major area of interest in longevity research. Throughout the conversation, Renee shares the latest findings on fasting-mimicking protocols, including their potential effects on autophagy, biological age, metabolic health, body composition, and fat loss. She explains how these protocols may help support cellular cleanup, improve markers of health, and promote healthy aging. We also discuss why muscle preservation is critical during any longevity intervention, especially for women approaching menopause and beyond. Renee shares insights into fasting, stress hormones, menstrual cycles, fertility considerations, and who may or may not be appropriate candidates for fasting-mimicking programs. Whether you're interested in longevity, healthy aging, nutrition science, or optimizing your metabolic health, this episode offers a fascinating look at one of the most researched approaches in the fasting and longevity space. - - - - - About the Guest: Renee Fitton, MS, RD, is a registered dietitian specializing in longevity nutrition, fasting science, and metabolic health. She serves as Vice President of Education and Growth at Prolon and is the co-founder of Heali AI. Renee is passionate about translating complex nutrition and longevity research into practical strategies that help individuals optimize their health, improve metabolic function, and support healthy aging through evidence-based nutrition approaches. Website: https://prolonlife.com/products/dr-talks [https://prolonlife.com/products/dr-talks] - - - - - Hormone Heroines Instagram: ⁠https://www.instagram.com/hormone_heroines/⁠ [https://www.instagram.com/hormone_heroines/] TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@hormone_heroines⁠ [https://www.tiktok.com/@hormone_heroines] Youtube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@HormoneHeroines⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://www.youtube.com/@HormoneHeroines] Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.blossominglongevity.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://www.blossominglongevity.com/] Shop Supplements: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://partnerships.timeline.com/BLOSSOMINGLONGEVIT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://partnerships.timeline.com/BLOSSOMINGLONGEVITY] Subscribe: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb], ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060] & ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠iHeart⁠⁠⁠⁠ [https://iheart.com/podcast/305165609/] - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/ [https://drtalks.com/podcast-service/]

Detox, Hormones & Hidden Toxins: What Every Woman Needs to Know

In this episode of Hormone Heroines, we sit down with Jeff Hoyt, wellness innovator and founder of Zeolite Labs, to explore the growing impact of environmental toxins on hormone health and overall wellness. Jeff explains how modern life exposes us to a wide range of toxic stressors, including heavy metals, microplastics, environmental pollutants, poor air quality, contaminated water, and chronic emotional stress. Together, we discuss how these exposures may contribute to inflammation, hormone disruption, and long-term health challenges. Throughout the conversation, Jeff shares his perspective on why the body stores toxins in tissues such as fat, bone, and organs. He explains how this may serve as a short-term survival strategy when the body is unable to efficiently process and eliminate toxic compounds. We also explore the relationship between toxins and hormone health, including the potential impact of endocrine-disrupting chemicals and xenoestrogens found in plastics and other environmental contaminants. Jeff discusses how chronic toxic exposure and inflammation may contribute to hormone imbalances and affect overall health. - - - - - About the Guest: Jeff Hoyt is a wellness innovator, educator, and founder of Zeolite Labs, a company focused on developing zeolite-based products designed to support detoxification and wellness. Jeff is passionate about helping individuals understand environmental toxicity, heavy metals, detoxification strategies, and the role of natural binders in supporting the body's elimination pathways. Through his educational work, he aims to make complex topics surrounding detoxification and health more accessible to practitioners and consumers alike. - - - - - Social Handles Website: https://www.zeolitelabs.com/ [https://www.zeolitelabs.com/] Facebook: https://www.facebook.com/zeolitelabs/ [https://www.facebook.com/zeolitelabs/] Instagram: https://www.instagram.com/zeolitelabs/ [https://www.instagram.com/zeolitelabs/] - - - - - Hormone Heroines Instagram: https://www.instagram.com/hormone_heroines/ [https://www.instagram.com/hormone_heroines/] TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@hormone_heroines [https://www.tiktok.com/@hormone_heroines] Youtube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@HormoneHeroines⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://www.youtube.com/@HormoneHeroines] Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.blossominglongevity.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://www.blossominglongevity.com/] Shop Supplements: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://partnerships.timeline.com/BLOSSOMINGLONGEVIT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://partnerships.timeline.com/BLOSSOMINGLONGEVITY] Subscribe: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://open.spotify.com/show/3Suq9AdUp9Aq10PyuCfVtb], ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ [https://podcasts.apple.com/us/podcast/hormone-heroines-podcast/id1851547060] & ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠iHeart⁠⁠⁠⁠ [https://iheart.com/podcast/305165609/] - - - - - PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com https://drtalks.com/podcast-service/ [https://drtalks.com/podcast-service/]