Practice Point®: Hematology

Episode 46 - What's New Doc? End-of-the-Year Updates on CAR T-cell Therapy in Multiple Myeloma Podcast

29 min · 17. dec. 2025
episode Episode 46 - What's New Doc? End-of-the-Year Updates on CAR T-cell Therapy in Multiple Myeloma Podcast cover

Description

CAR T-cell therapies have transformed the management of several previously incurable, treatment-refractory hematologic malignancies, including Multiple Myeloma (MM). With two CAR T-cell products now approved, and additional under investigation, the therapeutic landscape continues to evolve rapidly. In this educational podcast, Dr. Joseph Mikhael highlights key advances in CAR T-cell therapy for MM. He reviews the most impactful data published or presented in 2025 and offers expert insight into how these emerging findings may shape current and future treatment strategies. Launch/Release Date: December 17, 2025 Activity Expiration Date: November 30, 2026 FACULTY Joseph Mikhael, MD, MEd, FRCPC, FACP, FASCO Professor, Clinical Genomics and Therapeutics Translational Genomics Research Institute (TGen), City of Hope Cancer Center Chief Medical Officer International Myeloma Foundation This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/whats-new-doc-end-of-the-year-updates-on-car-t-cell-therapy-in-multiple-myeloma-podcast] prior to listening to this podcast.

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All episodes

51 episodes

episode Episode 51 - Podcast: What I'd Do Differently Tomorrow - Part 5 of RRMM Podcasts: Practical Insights for the First Relapse artwork

Episode 51 - Podcast: What I'd Do Differently Tomorrow - Part 5 of RRMM Podcasts: Practical Insights for the First Relapse

Managing relapsed/refractory multiple myeloma (RRMM), particularly at first relapse, requires timely, evidence-based decisions in an increasingly complex treatment landscape. As therapeutic options continue to expand and clinical guidance evolves, healthcare professionals must navigate challenges related to risk stratification, treatment selection, sequencing strategies, and the integration of emerging immunotherapies into practice. Clinicians may also face uncertainty in distinguishing mechanisms of action, managing immune-related toxicities, and selecting appropriate therapies in the context of treatment resistance. Additionally, real-world barriers such as staffing shortages, infusion capacity constraints, and workflow demands can complicate the implementation of optimal care. This podcast series features expert-led conversations that deliver practical insights and real-world strategies to support confident, guideline-informed decision-making in the management of RRMM. Launch Date/Release: July 2, 2026 Expiration Date: August 31, 2027 FACULTY Ajai Chari, MD Professor of Clinical Medicine University of California, San Francisco Sagar Lonial, MD, FACP, FASCO Chair and Professor Department of Hematology and Medical Oncology Anne and Bernard Gray Family Chair in Cancer Chief Medical Officer Winship Caner Institute | Emory University This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/rrmm-podcasts-practical-insights-for-the-first-relapse] prior to listening to this podcast.

2. juli 20267 min
episode Episode 50 - Podcast: From Knowing to Doing: Overcoming Real-World Barriers - Part 4 of RRMM Podcasts: Practical Insights for the First Relapse artwork

Episode 50 - Podcast: From Knowing to Doing: Overcoming Real-World Barriers - Part 4 of RRMM Podcasts: Practical Insights for the First Relapse

Managing relapsed/refractory multiple myeloma (RRMM), particularly at first relapse, requires timely, evidence-based decisions in an increasingly complex treatment landscape. As therapeutic options continue to expand and clinical guidance evolves, healthcare professionals must navigate challenges related to risk stratification, treatment selection, sequencing strategies, and the integration of emerging immunotherapies into practice. Clinicians may also face uncertainty in distinguishing mechanisms of action, managing immune-related toxicities, and selecting appropriate therapies in the context of treatment resistance. Additionally, real-world barriers such as staffing shortages, infusion capacity constraints, and workflow demands can complicate the implementation of optimal care. This podcast series features expert-led conversations that deliver practical insights and real-world strategies to support confident, guideline-informed decision-making in the management of RRMM. Launch Date/Release: July 2, 2026 Expiration Date: August 31, 2027 FACULTY Ajai Chari, MD Professor of Clinical Medicine University of California, San Francisco Sagar Lonial, MD, FACP, FASCO Chair and Professor Department of Hematology and Medical Oncology Anne and Bernard Gray Family Chair in Cancer Chief Medical Officer Winship Caner Institute | Emory University This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/rrmm-podcasts-practical-insights-for-the-first-relapse] prior to listening to this podcast.

2. juli 20267 min
episode Episode 49 - Podcast: Bispecific Antibodies Across Targets: Practical Integration in RRMM - Part 3 of RRMM Podcasts: Practical Insights for the First Relapse artwork

Episode 49 - Podcast: Bispecific Antibodies Across Targets: Practical Integration in RRMM - Part 3 of RRMM Podcasts: Practical Insights for the First Relapse

Managing relapsed/refractory multiple myeloma (RRMM), particularly at first relapse, requires timely, evidence-based decisions in an increasingly complex treatment landscape. As therapeutic options continue to expand and clinical guidance evolves, healthcare professionals must navigate challenges related to risk stratification, treatment selection, sequencing strategies, and the integration of emerging immunotherapies into practice. Clinicians may also face uncertainty in distinguishing mechanisms of action, managing immune-related toxicities, and selecting appropriate therapies in the context of treatment resistance. Additionally, real-world barriers such as staffing shortages, infusion capacity constraints, and workflow demands can complicate the implementation of optimal care. This podcast series features expert-led conversations that deliver practical insights and real-world strategies to support confident, guideline-informed decision-making in the management of RRMM. Launch Date/Release: July 2, 2026 Expiration Date: August 31, 2027 FACULTY Ajai Chari, MD Professor of Clinical Medicine University of California, San Francisco Sagar Lonial, MD, FACP, FASCO Chair and Professor Department of Hematology and Medical Oncology Anne and Bernard Gray Family Chair in Cancer Chief Medical Officer Winship Caner Institute | Emory University This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/rrmm-podcasts-practical-insights-for-the-first-relapse] prior to listening to this podcast.

2. juli 202614 min
episode Episode 48 - Podcast: Making Sense of Immunotherapy Targets - Part 2 of RRMM Podcasts: Practical Insights for the First Relapse artwork

Episode 48 - Podcast: Making Sense of Immunotherapy Targets - Part 2 of RRMM Podcasts: Practical Insights for the First Relapse

Managing relapsed/refractory multiple myeloma (RRMM), particularly at first relapse, requires timely, evidence-based decisions in an increasingly complex treatment landscape. As therapeutic options continue to expand and clinical guidance evolves, healthcare professionals must navigate challenges related to risk stratification, treatment selection, sequencing strategies, and the integration of emerging immunotherapies into practice. Clinicians may also face uncertainty in distinguishing mechanisms of action, managing immune-related toxicities, and selecting appropriate therapies in the context of treatment resistance. Additionally, real-world barriers such as staffing shortages, infusion capacity constraints, and workflow demands can complicate the implementation of optimal care. This podcast series features expert-led conversations that deliver practical insights and real-world strategies to support confident, guideline-informed decision-making in the management of RRMM. Launch Date/Release: July 2, 2026 Expiration Date: August 31, 2027 FACULTY Ajai Chari, MD Professor of Clinical Medicine University of California, San Francisco Sagar Lonial, MD, FACP, FASCO Chair and Professor Department of Hematology and Medical Oncology Anne and Bernard Gray Family Chair in Cancer Chief Medical Officer Winship Caner Institute | Emory University This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/rrmm-podcasts-practical-insights-for-the-first-relapse] prior to listening to this podcast.

2. juli 202615 min
episode Episode 47 - Podcast: First Relapse Sets the Course - Part 1 of RRMM Podcasts: Practical Insights for the First Relapse artwork

Episode 47 - Podcast: First Relapse Sets the Course - Part 1 of RRMM Podcasts: Practical Insights for the First Relapse

Managing relapsed/refractory multiple myeloma (RRMM), particularly at first relapse, requires timely, evidence-based decisions in an increasingly complex treatment landscape. As therapeutic options continue to expand and clinical guidance evolves, healthcare professionals must navigate challenges related to risk stratification, treatment selection, sequencing strategies, and the integration of emerging immunotherapies into practice. Clinicians may also face uncertainty in distinguishing mechanisms of action, managing immune-related toxicities, and selecting appropriate therapies in the context of treatment resistance. Additionally, real-world barriers such as staffing shortages, infusion capacity constraints, and workflow demands can complicate the implementation of optimal care. This podcast series features expert-led conversations that deliver practical insights and real-world strategies to support confident, guideline-informed decision-making in the management of RRMM. Launch Date/Release: July 2, 2026 Expiration Date: August 31, 2027 FACULTY Ajai Chari, MD Professor of Clinical Medicine University of California, San Francisco Sagar Lonial, MD, FACP, FASCO Chair and Professor Department of Hematology and Medical Oncology Anne and Bernard Gray Family Chair in Cancer Chief Medical Officer Winship Caner Institute | Emory University This podcast provides accredited continuing education credits. To receive your credit, please read the accreditation information provided in this link [https://www.practicepointcme.com/CMEHome/rrmm-podcasts-practical-insights-for-the-first-relapse] prior to listening to this podcast.

2. juli 202612 min