The Gold Standard with Mark S. Gold, MD

"Ketamine, Yale Psychiatry & the Future of Mental Health" with Dr. John Krystal

53 min · 1. juni 2026
episode "Ketamine, Yale Psychiatry & the Future of Mental Health" with Dr. John Krystal cover

Description

In this landmark episode of The Gold Standard, Dr. Mark Gold speaks with Dr. John Krystal, Chair of Psychiatry at Yale School of Medicine and the longtime Editor‑in‑Chief of Biological Psychiatry. This in‑depth conversation traces the scientific origins of ketamine’s rapid antidepressant effects, the unique neuroscience culture at Yale, and how mechanism‑driven psychiatry is reshaping treatment for depression, PTSD, addiction, and beyond. This episode goes far beyond ketamine alone. Dr. Krystal reflects on how psychiatry moved from monoamine theories toward circuit‑based neuroscience, and why depression, trauma, and addiction require fundamentally different ways of thinking.

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episode "Integrated Psychiatry, Leadership at Mayo Clinic, and Global Mental Health" with Dr. Teresa Rummans artwork

"Integrated Psychiatry, Leadership at Mayo Clinic, and Global Mental Health" with Dr. Teresa Rummans

Welcome to The Gold Standard with Dr. Mark Gold! In this insightful episode, Dr. Gold is joined by his longtime friend and esteemed colleague, Dr. Teresa Rummans, Professor of Psychiatry and former Chair at the Mayo Clinic College of Medicine. Together, they explore Dr. Rummans’ remarkable career, the unique Mayo Clinic psychiatry model, and the evolving landscape of mental health and addiction treatment. This conversation offers a rare glimpse into a distinguished psychiatrist’s journey blending clinical excellence, research, mentorship, and humanitarian work. Dr. Rummans’ passion for integrated care and her visionary leadership at Mayo Clinic provide inspiration for clinicians, researchers, and anyone interested in the future of mental health care.

1. maj 202650 min