The Readout Loud

394: Eli Lilly's deal man, Allogene's off-the-shelf CAR-T, and Merck's Terns buy

On this week’s episode of "The Readout LOUD": Allison DeAngelis is still away, leaving Elaine Chen and Adam Feuerstein to mind the podcasting store. You've been warned. Eli Lilly’s deal man Jake van Naarden [https://www.statnews.com/2026/03/25/eli-lilly-cancer-drug-pipeline-fueled-loxo-oncology-jacob-van-naarden/] is very, very busy, so what does that mean for biotech and pharma? Speaking of deals, Merck is buying [https://www.statnews.com/2026/03/25/merck-terns-pharmaceuticals-leukemia-tern701/] Terns for nearly $7 billion. Why are some people mad about it? You might be surprised to hear this, but off-the-shelf CAR-T therapies for cancer are still a thing. We preview an interesting data readout coming soon from Allogene Therapeutics [https://www.statnews.com/2026/03/26/allogene-car-t-lymphoma-treatment-study/]. And finally, someone forgot to tell Wave Life Sciences that weight loss drugs are supposed to help people lose weight.

393: A conversation with the 'godfather' of biotech

On this week's episode of "The Readout LOUD," we bring you a special conversation with Stelios Papadapolous, also know as the "godfather" of biotech. He sat down for an on-stage chat with our colleague Damian Garde Thursday afternoon during STAT’s Breakthrough Summit East event in New York City. We also chat about the latest biotech news, including new weight loss data from Structure Therapeutics and Eli Lilly, plus recent staff departures from the Food and Drug Administration.

392: Epstein's pal attempts a biotech comeback, and Prasad exits the FDA

How was a known friend of Jeffrey Epstein able to raise $100 million, with the help of a prominent biotech VC? And will Vinay Prasad return to the Food and Drug Administration for a "three-peat"? Damian Garde joins Allison, Adam, and Elaine to discuss his article about Boris Nikolic, a well-connected biotech investor with deep ties to Jeffrey Epstein, who has raised a new biotech investment firm. The hosts also talk about Prasad's second exit from the FDA and a congressman's probing of the agency's rare disease drug denials. And they recap Novo Nordisk and Hims' detente and Xenon Pharmaceuticals' promising seizure data.

391: Breaching the IBD efficacy ceiling, and sham surgeries

Will drugmakers finally be able to breach the efficacy ceiling in inflammatory bowel disease? And is the Food and Drug Administration being flexible enough with rare disease treatments? Spyre Therapeutics CEO Cameron Turtle joins the podcast to discuss his company's experimental IBD medications, and whether the drug industry is scraping the barrel in the search for better treatments. We also discuss the latest news in the life sciences, including the ongoing debate between the FDA and UniQure [https://www.statnews.com/2026/03/02/uniqure-huntingtons-disease-fda-blocked/] over its Huntington's disease therapy, as well as Moderna's mammoth patent settlement [https://www.statnews.com/2026/03/03/moderna-settles-covid-vaccine-suit-roivant/].

390: FDA turmoil, election intrigue, AI, and more

On "The Readout LOUD" this week: Adam Feuerstein, solo. His usual co-hosts Allison DeAngelis and Elaine Chen took some time off, so Adam manned the podcast mic himself. Adam thought, quite understandably, that our cherished listeners wouldn’t want to hear him drone on for 30 minutes, so he thankfully found some help. Jared Holz, health care sector specialist at Mizuho Securities, agreed to be Adam’s podcasting wingman for this week’s show. They ran through a menu of takes on biotech stock performance, M&A, Food and Drug Administration turmoil, election intrigue, and artificial intelligence.