Genetics in Your World

Mapping Whole-organism Genetic Comorbidities Across Model Species Using Unified Ontologies—A Conversation with Caitlin Peaslee

In this episode of Genetics in Your World, GSA Early Career Scientists Multimedia Subcommittee member Luke Arnce interviews Caitlin Peaslee of the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University about her research. Read her paper titled, "Mapping whole-organism genetic comorbidities across model species using unified ontologies," published in the April 2026 issue of GENETICS: https://doi.org/10.1093/genetics/iyag038 [https://doi.org/10.1093/genetics/iyag038] This study developed a cross-species computational framework, CoMo DBM, to analyze 204 mouse genes that caused non-obstructive azoospermia and mapped their phenotype associations across human, zebrafish, fruit fly, and roundworm databases. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ [http://creativecommons.org/licenses/by/3.0/] #GeneEditing #cancer #GeneOntology ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

Bridging Disciplines: How a Theory Meant to Aid in Saving Plant and Animal Species is Helping Scientists Reconsider an Evolutionary Approach to Cancer Treatment — A Conversation with Srishti Patil and Dr. Robert Noble

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee advisor Sarah Renee Phillips interviews Srishti Patil of the German Cancer Research Center and Dr. Robert Noble of City St. George's, University of London about their research. Read their paper titled, “Preventing evolutionary rescue in cancer using two-strike therapy,” published in the February 2026 issue of GENETICS: https://doi.org/10.1093/genetics/iyaf255 [https://doi.org/10.1093/genetics/iyaf255]. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ [http://creativecommons.org/licenses/by/3.0/] #evolution #cancer #GeneticRescue #variation #selection #mutation ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

The Evolutionary Price of Family Ties in Caenorhabditis — A Conversation with Dr. Matt Rockman

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Debraj Manna interviews Dr. Matt Rockman of New York University about inbreeding depression in Caenorhabditis elegans. Read Dr. Rockman's paper titled, “Variation in inbreeding depression within and among Caenorhabditis species,” published in the December 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf200 [https://doi.org/10.1093/g3journal/jkaf200]. Special thanks to the Production Team for this episode, ECS Multimedia Subcommittee members Debraj Manna, interviewer; Sara Shahba, researcher; and Laetitia Chauve, Audio Quality Control Coordinator. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ [http://creativecommons.org/licenses/by/3.0/] #genetics #Celegans #caenorhabditis #InbreedingDepression ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

Variation Reconsidered: Selection Schemes for Phenotypic Variability Beyond Trait Means — A Conversation with Dr. Shraddha Lall

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee co-chair Sarah Renee Phillips interviews Dr. Shraddha Lall of Harvard University about the evolution of variation in behavior in Drosophila. Read Dr. Lall’s paper titled, “Family-based selection: An efficient method for increasing phenotypic variability,” published in the October 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf165 [https://doi.org/10.1093/g3journal/jkaf165]. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ [http://creativecommons.org/licenses/by/3.0/] #genetics #evolution #Drosophila #behavior #variation #selection ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

Age Is Just A Number: Mapping Longevity in Diversity Outbred Mice – A Conversation with Dr. Gary Churchill

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Faye Romero interviews Dr. Gary Churchill of the Jackson Laboratory about longevity-associated loci in diversity outbred mice. Read Dr. Churchill’s paper titled, “Analysis of lifespan across diversity outbred mouse studies identifies multiple longevity-associated loci,” published in the August 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/genetics/iyaf081 [https://urldefense.com/v3/__https:/doi.org/10.1093/genetics/iyaf081__;!!CGUSO5OYRnA7CQ!b5NFlhzqmyG4WJAowfbrd0jhR_dhaK8y2cHT2G4tcFthQzhRiGHNsx1n6VDwzNznjC4YNnbptpuTSLZq2986P2VAKaD1C_Q8HIWZ4A$] Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ [http://creativecommons.org/licenses/by/3.0/] ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.