NPLEX on the Go

Gastroenterology 2: This Colon’s on Fire

In this episode, we work through a classic inflammatory bowel disease case featuring recurrent bloody diarrhea, urgency, and continuous colonic inflammation. Using four board-style questions, we review the key distinctions between ulcerative colitis and Crohn’s disease across pathology, anatomy, physiology, and complications. Topics covered include: • Crypt abscesses and mucosal inflammation in ulcerative colitis • Why the rectum is always involved in UC • Vitamin K deficiency and chronic inflammatory disease • Toxic megacolon vs fistulas and strictures • High-yield UC vs Crohn’s comparisons for board exams Perfect for quick review during commutes, workouts, or study breaks. Disclaimer: This podcast is for educational purposes only and does not constitute medical advice. Show Notes at www.variabilityscience.com/nplexonthegopodcast.

Integumentary 1: The Itch is Real

In this episode, a young woman buys a new bracelet, and within two days she’s dealing with an intensely itchy, blistering rash that keeps her up at night. What’s going on beneath the skin? We’ll peel back the layers — literally — to explore the immune mechanisms, hypersensitivity reactions, and how to tackle board-style questions that test your knowledge of anatomy, immunology, microbiology, and pathology. Show Notes at www.variabilityscience.com/nplexonthegopodcast.

Microbiology 1: Pus Happens

In this episode, we dive into a clinical case featuring a 25-year-old AMAB patient with a painful, swollen lesion on his left thigh. Through 4 questions across Anatomy, Physiology, Pathology, and Biochemistry, we’ll walk through the key features, connect them to what’s happening at the tissue level, and explore the basic science behind the body’s response to this kind of infection. Show Notes at www.variabilityscience.com/nplexonthegopodcast.

Endocrinology 1: Milking the Truth

What do a massive postpartum hemorrhage, an ‘empty’ space in the skull, and an inability to breastfeed have in common? We’ll find out today as we follow the endocrine aftermath of a postpartum hemorrhage and uncover how a single event can lead to multi-hormone deficiency. Show Notes at www.variabilityscience.com/nplexonthegopodcast.

Pulmonology 1: Wheeze the Day

In this episode, we dive into a condition where the immune system turns the airways into a battleground. You’ll hear how allergens trigger smooth muscle spasms, why eosinophils leave behind crystal footprints, and what changes in lung volumes reveal during an attack. Four angles—pathology, anatomy, physiology, and immunology—coming together in one wheezy case. Show Notes at www.variabilityscience.com/nplexonthegopodcast.