Genome modelling and design across all domains of life with Evo 2

A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome

This article "A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome" is published in NATURE. Author: Manpreet Kaur Journal: NATURE Year: 2026 Podcast type: Expert The authors are: * Manpreet Kaur * Dmitrii Y. Travin * Max J. Berger * Manoj Jangra * Martino Morici * Haaris A. Safdari * Dorota Klepacki * Wenliang Wang * Michael Cook * Sommer Chou * Allison K. Guitor * Kalinka Koteva * Min Xu * Linda Ejim * Aline Fiebig * Yeganeh Yousefi * Brian K. Coombes * Lesley Macneil * Nora Vázquez-Laslop * Alexander S. Mankin * Daniel N. Wilson * Gerard D. Wright Affiliations: McMaster University, Hamilton, Ontario, Canada. University of Illinois at Chicago, Chicago, IL, USA. University of Hamburg, Hamburg, Germany.

A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome

This article "A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome" is published in NATURE. Author: Manpreet Kaur Journal: NATURE Year: 2026 Podcast type: Short The authors are: * Manpreet Kaur * Dmitrii Y. Travin * Max J. Berger * Manoj Jangra * Martino Morici * Haaris A. Safdari * Dorota Klepacki * Wenliang Wang * Michael Cook * Sommer Chou * Allison K. Guitor * Kalinka Koteva * Min Xu * Linda Ejim * Aline Fiebig * Yeganeh Yousefi * Brian K. Coombes * Lesley Macneil * Nora Vázquez-Laslop * Alexander S. Mankin * Daniel N. Wilson * Gerard D. Wright Affiliations: McMaster University, Hamilton, Ontario, Canada. University of Illinois at Chicago, Chicago, IL, USA. University of Hamburg, Hamburg, Germany.

Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs

This article "Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs" is published in NATURE COMMUNICATIONS. Author: Leyuan Li Journal: NATURE COMMUNICATIONS Year: 2025 Podcast type: Expert The authors are: * Leyuan Li * Caitlin M. A. Simopoulos * Janice Mayne * Zhibin Ning * Xin Zhang * Mona Hamada * James Butcher * Joeselle M. Serrana * Luman Wang * Kai Cheng * Hongye Qin * Krystal Walker * Xu Zhang * Alain Stintzi * Daniel Figeys Affiliations: National Center for Protein Sciences (Beijing), Beijing, China. University of Ottawa, Ottawa, ON, Canada. Stockholm University, Stockholm, Sweden. Peking University, Beijing, China. Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, UK. University of East Anglia, Norwich, Norfolk, UK.

Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs

This article "Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs" is published in NATURE COMMUNICATIONS. Author: Leyuan Li Journal: NATURE COMMUNICATIONS Year: 2025 Podcast type: Short The authors are: * Leyuan Li * Caitlin M. A. Simopoulos * Janice Mayne * Zhibin Ning * Xin Zhang * Mona Hamada * James Butcher * Joeselle M. Serrana * Luman Wang * Kai Cheng * Hongye Qin * Krystal Walker * Xu Zhang * Alain Stintzi * Daniel Figeys Affiliations: National Center for Protein Sciences (Beijing), Beijing, China. University of Ottawa, Ottawa, ON, Canada. Stockholm University, Stockholm, Sweden. Peking University, Beijing, China. Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, UK. University of East Anglia, Norwich, Norfolk, UK.

Universal transcriptomic hallmarks of mammalian ageing and mortality

This article "Universal transcriptomic hallmarks of mammalian ageing and mortality" is published in NATURE. Author: Alexander Tyshkovskiy Journal: NATURE Year: 2026 Podcast type: Short The authors are: * Alexander Tyshkovskiy * Daria Kholdina * Maria Davitadze * Adrian Molière * Alibek Moldakozhayev * Yoshiyasu Tongu * Tomoko Kasahara * Dmitrii Glubokov * Alec Eames * Leonid M. Kats * Anastasiya Vladimirova * Kejun Ying * Hanna Liu * Bohan Zhang * Uma Khasanova * Mahdi Moqri * Jeremy M. Van Raamsdonk * David E. Harrison * Randy Strong * Takaaki Abe * Sergey E. Dmitriev * Vadim N. Gladyshev Affiliations: Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Moscow State University, Moscow, Russia. ETH Zürich, Zurich, Switzerland. McGill University, Montreal, Quebec, Canada. Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Tohoku University, Sendai, Japan. Heidelberg University, Heidelberg, Germany. Harvard University, Boston, MA, USA. Massachusetts College of Pharmacy and Health Sciences, Boston, MA, USA. Stanford University, Stanford, CA, USA. The Jackson Laboratory, Bar Harbor, ME, USA. The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. Broad Institute of Harvard and MIT, Cambridge, MA, USA.