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Intestinal interoceptive dysfunction drives age-associated cognitive decline

This article "Intestinal interoceptive dysfunction drives age-associated cognitive decline" is published in NATURE. Author: Timothy O. Cox Journal: NATURE Year: 2026 Podcast type: Short The authors are: * Timothy O. Cox * Ashwarya S. Devason * Alan de Araujo * Sydney Mason * Madhav Subramanian * Andrea F. M. Salvador * Hélène C. Descamps * Junwon Kim * Yixuan Zhu * Lev Litichevskiy * Sunhee Jung * Won-Suk Song * Adrián Cortés-Martín * Nathan T. Henderson * Kuei-Pin Huang * Thao Nguyen * Wisath Sae-Lee * Iboro C. Umana * Maria Sacta * Ryan J. Rahman * Stephen Wisser * J. Andrew D. Nelson * Ilona Golynker * Alana M. McSween * Eric F. Hohmann * Shaan Patel * Anna L. Bub * Clara Soekler * Niklas Blank * Kevt'her Hoxha * Lavinia Boccia * Andrea C. Wong * Klaas Bahnsen * Jihee Kim * Natalie Biderman * Dina Abbasian * Clarissa Shoffler * Christopher Petucci * Fiona E. McAllister * Amber L. Alhadeff * Marc V. Fuccillo * Colin Hill * Cholsoon Jang * J. Nicholas Betley * Guillaume de Lartigue * Virginia Y.-M. Lee * Maayan Levy * Christoph A. Thaiss Affiliations: University of Pennsylvania, Philadelphia, PA, USA. Monell Chemical Senses Center, Philadelphia, PA, USA. Arc Institute, Palo Alto, CA, USA. Stanford University, Stanford, CA, USA. University of California Irvine, Irvine, CA, USA. University College Cork, Cork, Ireland. Calico Life Sciences LLC, San Francisco, CA, USA. Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

This article "Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain" is published in MICROBIOME. Author: Aimée Parker Journal: MICROBIOME Year: 2022 Podcast type: Short The authors are: * Aimée Parker * Stefano Romano * Rebecca Ansorge * Asmaa Aboelnour * Gwenaelle Le Gall * George M. Savva * Matthew G. Pontifex * Andrea Telatin * David Baker * Emily Jones * David Vauzour * Steven Rudder * L. Ashley Blackshaw * Glen Jeffery * Simon R. Carding Affiliations: Quadram Institute, Norwich, UK. University College London, London, UK. University of East Anglia, Norwich, UK.

Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition

This article "Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition" is published in NATURE COMMUNICATIONS. Author: Serena Boscaini Journal: NATURE COMMUNICATIONS Year: 2026 Podcast type: Short The authors are: * Serena Boscaini * Thomaz F. S. Bastiaanssen * Gerard M. Moloney * Federica Bergamo * Laila Zeraik * Caroline O'Leary * Aimone Ferri * Maha Irfan * Maaike van der Rhee * Thaïs I. F. Lindemann * Elizabeth Schneider * Arthi Chinna Meyyappan * Kirsten Berding Harold * Caitríona M. Long-Smith * Carina Carbia * Kenneth J. O'Riordan * José Fernando Rinaldi de Alvarenga * Nicole Tosi * Daniele Del Rio * Alice Rosi * Letizia Bresciani * Pedro Mena * Gerard Clarke * John F. Cryan Affiliations: University College Cork, Cork, Ireland. University of Parma, Parma, Italy.

Genome modelling and design across all domains of life with Evo 2

This article "Genome modelling and design across all domains of life with Evo 2" is published in NATURE. Author: Garyk Brixi Journal: NATURE Year: 2026 Podcast type: Short The authors are: * Garyk Brixi * Matthew G. Durrant * Jerome Ku * Mohsen Naghipourfar * Michael Poli * Gwanggyu Sun * Greg Brockman * Daniel Chang * Alison Fanton * Gabriel A. Gonzalez * Samuel H. King * David B. Li * Aditi T. Merchant * Eric Nguyen * Chiara Ricci-Tam * David W. Romero * Jonathan C. Schmok * Ali Taghibakhshi * Anton Vorontsov * Brandon Yang * Myra Deng * Liv Gorton * Nam Nguyen * Nicholas K. Wang * Michael T. Pearce * Elana Simon * Etowah Adams * Zachary J. Amador * Euan A. Ashley * Stephen A. Baccus * Haoyu Dai * Steven Dillmann * Stefano Ermon * Daniel Guo * Michael H. Herschl * Rajesh Ilango * Ken Janik * Amy X. Lu * Reshma Mehta * Mohammad R. K. Mofrad * Madelena Y. Ng * Jaspreet Pannu * Christopher Ré * John St. John * Jeremy Sullivan * Joseph Tey * Ben Viggiano * Kevin Zhu * Greg Zynda * Daniel Balsam * Patrick Collison * Anthony B. Costa * Tina Hernandez-Boussard * Eric Ho * Ming-Yu Liu * Thomas McGrath * Kimberly Powell * Sudarshan Pinglay * Dave P. Burke * Hani Goodarzi * Patrick D. Hsu * Brian L. Hie Affiliations: Arc Institute, Palo Alto, CA, USA. Evo 2 Core Team, Palo Alto, CA, USA. Stanford University, Stanford, CA, USA. University of California, Berkeley, Berkeley, CA, USA. Liquid AI, San Francisco, CA, USA. Independent Researcher, San Francisco, CA, USA. NVIDIA, Santa Clara, CA, USA. Goodfire, San Francisco, CA, USA. Columbia University, New York, NY, USA. University of Washington, Seattle, WA, USA. Johns Hopkins University, Baltimore, MD, USA. University of California, San Francisco, San Francisco, CA, USA. OpenAI, San Francisco, CA, USA.

NSD2 targeting reverses plasticity and drug resistance in prostate cancer

This article "NSD2 targeting reverses plasticity and drug resistance in prostate cancer" is published in Nature. Author: Jia J. Li Journal: Nature Year: 2025 Podcast type: Short The authors are: * Jia J. Li * Alessandro Vasciaveo * Dimitris Karagiannis * Zhen Sun * Kristjan H. Gretarsson * Xiao Chen * Ouathek Ouerfelli * Fabio Socciarelli * Ziv Frankenstein * Hanyang Dong * Min Zou * Wei Yuan * Guangli Yang * Gabriel M. Aizenman * Tania Pannellini * Xinjing Xu * Himisha Beltran * Yu Chen * Kevin Gardner * Brian D. Robinson * Johann de Bono * Or Gozani * Cory Abate-Shen * Mark A. Rubin * Massimo Loda * Charles L. Sawyers * Andrea Califano * Chao Lu * Michael M. Shen Affiliations: Jia J. Li, Cory Abate-Shen, Andrea Califano, Michael M. Shen, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Alessandro Vasciaveo, Cory Abate-Shen, Andrea Califano, Michael M. Shen, Department of Systems Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Dimitris Karagiannis, Kristjan H. Gretarsson, Xiao Chen, Chao Lu, Michael M. Shen, Department of Genetics and Development, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Cory Abate-Shen, Michael M. Shen, Department of Urology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Alessandro Vasciaveo, Dimitris Karagiannis, Kristjan H. Gretarsson, Xiao Chen, Ziv Frankenstein, Min Zou, Cory Abate-Shen, Andrea Califano, Chao Lu, Michael M. Shen, Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Center for Data Science and Artificial Intelligence, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Center for Therapeutics Discovery, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Zhen Sun, Yu Chen, Charles L. Sawyers, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA Ouathek Ouerfelli, Guangli Yang, Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA Fabio Socciarelli, Tania Pannellini, Brian D. Robinson, Massimo Loda, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA Ziv Frankenstein, Kevin Gardner, Cory Abate-Shen, Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Hanyang Dong, Or Gozani, Department of Biology, Stanford University, Stanford, CA, USA Min Zou, Cory Abate-Shen, Department of Molecular Pharmacology and Therapeutics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Wei Yuan, Johann de Bono, Division of Clinical Studies, The Institute of Cancer Research, London, UK Himisha Beltran, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA Yu Chen, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA Mark A. Rubin, Department of Biomedical Research, Bern Center for Precision Medicine, University of Bern, Bern, Switzerland Massimo Loda, Nuffield Department of Surgical Sciences, Lincoln College, University of Oxford, Oxford, UK Charles L. Sawyers, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA Andrea Califano, Department of Biomedical Informatics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Andrea Califano, Department of Biochemistry and Molecular Biophysics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA