Charlie James debates Democratic masculinity and is called by a listener.

A listener shares his diagnosis story; Charlie talks Trump and Biden's book.

During this segment of The Charlie James Show, a listener named Mike from Spartanburg called in to share his personal healthcare experience. He described how his persistent physical symptoms were repeatedly misdiagnosed by physicians who prescribed ineffective psychiatric medications. It wasn't until he researched his symptoms himself and successfully pushed for specific testing that he was correctly diagnosed with an H. pylori bacterial infection. Host Charlie James validated Mike's situation, agreeing that patients often intuitively understand their own bodies. James then previewed an upcoming national address by President Donald Trump, which he noted would detail specific evidence of Chinese interference in the 2020 election. The segment concluded with a humorous preview of a new book written by President Joe Biden, alongside criticism of Minnesota Governor Tim Walz.

A voter shares his views on Trump while an SC listener praises Ivermectin.

Dean, a caller from Hendersonville, stated he has voted for Trump three times and supports him, though he notes Trump missing a term may have allowed people to see the negative effects of the Biden administration on the economy before Trump's return. Host Charlie James then shared a recent study from the Fed attributing illegal immigration as a sole driver for a 30% increase in home prices and a 20% increase in rental prices, along with rising healthcare and auto insurance costs. Afterward, Barbara from Greenville called in to share her positive experience using the animal formulation of Ivermectin to treat her COVID-19 infection. She and James criticized Representative Davey Hiott for fighting against a bill that would have made the medication available over-the-counter and for making dismissive remarks telling citizens to go to a tractor supply store for horse paste.

SC Dem Sen candidate Dr. Andrews shares medical & policy views.

In this interview, South Carolina Democratic Senate candidate Dr. Annie Andrews explains that her decision to enter politics stemmed from witnessing systemic policy and healthcare issues firsthand during her 15-year career as a children's hospital pediatrician. She emphasizes that despite political divisions, South Carolinians share common goals like reducing living costs, improving roads, and securing quality education and affordable healthcare. While critiquing the profit-driven nature of the current healthcare system and calling for lower prescription drug costs, she favors pragmatic reforms over an immediate shift to a Medicare-for-All system. On social issues, Andrews supports reasonable abortion restrictions aligned with Roe v. Wade and views transgender care as a private matter between families and physicians. Additionally, she strongly supports funding law enforcement to help combat gun violence and advocates for comprehensive immigration reform that balances border security with humane treatment and clear paths to citizenship.

Charlie James analyzes how a lobbyist connection killed SC Ivermectin bill

Host Charlie James previews his upcoming interview with South Carolina Democratic Senate candidate Dr. Annie Andrews before revisiting the state's legislative battle over making Ivermectin an over-the-counter medication. Despite the bill passing nearly unanimously in both the House and Senate, it was ultimately sent back to the Agricultural Committee and effectively killed by Representative Davey Hiatt. Drawing on research from Diane Hardy of the Mom and Pop Alliance of South Carolina, James reveals that Representative Hiatt's son, Lander Hiatt, is a registered lobbyist for the Pharmaceutical Research and Manufacturers of America (PhRMA). He suggests that the bill's sudden defeat may have been directly influenced by this deep-seated lobbying connection to major pharmaceutical companies like Pfizer and Johnson & Johnson.

Charlie James debates Democratic masculinity and is called by a listener.

Host Charlie James begins the second hour of his Thursday afternoon show by playing a crowd chanting the Pledge of Allegiance and the national anthem, reminding listeners of his upcoming 4:35 PM interview with South Carolina Democratic Senate candidate Dr. Annie Andrews. He then launches into a segment arguing that the Democratic Party has a "man problem" and is struggling to appeal to male voters after years of promoting theories of "toxic masculinity". Highlighting an article from The Atlantic written by Russell Berman, James mocks progressive efforts to reclaim traditional masculinity by spotlighting blue-collar Democratic candidates like Brian Poindexter and utilizing running mates like Governor Tim Walz. He asserts that these depictions are nothing more than a superficial, theatrical pantomime of manhood. Finally, he takes a call from listener Dave in Spartanburg, who raises questions about how Dr. Andrews was recruited and whether she will remain a moderate or flip to progressive stances once elected.