Drugs.com - Monthly Update December 2025
This month, discover the Wegovy tablet, the first oral GLP-1 weight loss medication to be approved, Myqorzo's long-awaited treatment for obstructive hypertrophic cardiomyopathy, and several other exciting new FDA approvals. Explore these key stories and more in our December 2025 round-up.
* Wegovy [https://www.drugs.com/wegovy.html] (semaglutide) tablet, the first oral GLP-1 for weight loss, with significant efficacy in patient trials.
* Myqorzo [https://www.drugs.com/myqorzo.html] (aficamten), a long-awaited and major addition to obstructive hypertrophic cardiomyopathy treatment that improves exercise capacity.
* Exdensur [https://www.drugs.com/exdensur.html] (depemokimab-ulaa), a new long-term, add-on treatment for severe eosinophilic asthma with twice-yearly injections.
* Jaypirca [https://www.drugs.com/jaypirca.html] (pirtobrutinib), a non-covalent BTK inhibitor whose approval has been extended to include chronic lymphocytic leukemia and small lymphocytic lymphoma.
* Lerochol [https://www.drugs.com/lerochol.html] (lerodalcibep-liga), a third-generation, PCSK9 inhibitor for high cholesterol self-administered via a monthly injection.
* Breyanzi [https://www.drugs.com/breyanzi.html] (lisocabtagene maraleucel), a CAR T cell therapy with extended approval to include relapsed or refractory marginal zone lymphoma.
Chapters
* (00:00) - Intro
* (00:22) - Overview
* (00:34) - Wegovy
* (01:16) - Myqorzo
* (02:07) - Exdensur
* (02:56) - Jaypirca
* (03:31) - Lerochol
* (04:09) - Breyanzi
* (04:46) - Outro
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