The GuideLine

Podcast by Guidehouse

English

Technology & science

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About The GuideLine

Not every organization gets to “move fast and break things.” In regulated industries, the momentum behind tech modernization must be balanced with mission, risk, and public trust. How do you walk that line? Hosted by Stuart Brown, Guidehouse Global Technology Leader, The GuideLine tackles that question through candid interviews with both the regulated and the regulators: industry executives managing complex systems, public sector innovators shaping oversight and mission outcomes, and senior technologists translating requirements into architecture. Together, they unpack what’s changing as AI and other emerging tools move into the daily operations of high-accountability enterprises. The focus stays practical: what to build, what to scale, and what to rethink. Expect a mix of big-picture strategy and technical depth, along with actionable advice for those moving fast, but carefully, with today’s tech.

All episodes

2 episodes

Moonshot first, then tools: The way to AI value

AI value doesn’t start with tools. It starts with a clear ambition for how work should change. In this episode of The GuideLine, recorded at the Microsoft Government BizApps + Copilot Summit, Stuart Brown sits down with Ryan Cunningham, Corporate Vice President of Power Platform at Microsoft, to explore why the biggest blocker to AI impact is often not technical at all. It’s organizational. Stu and Ryan unpack what it takes to turn AI ambition into operational value. They discuss why the best starting point is a concrete problem worth solving, rather than the next shiny technology, why culture can often be the biggest barrier to progress, and why AI can be especially powerful in regulated industries as a force for greater consistency and lower risk. Along the way, they make the case that AI can’t sit with one specialized team anymore and why, for most organizations, this is still the beginning of the AI journey.

11 May 2026 - 26 min

The enterprise is changing. Are we?

Agentic AI is rewriting the rules of work—and not in the way most organizations are talking about it. In this inaugural episode of The GuideLine, Stuart Brown (Stu) speaks with Microsoft Corporate Vice President Ulrich Homann (Uli) about why the agentic shift is bigger than a technology upgrade or even a change-management effort. At its core, Uli argues, it reshapes how decisions get made, how work gets done, and what an enterprise really is. Stu and Uli map the foundations behind AI, share a three part framework for understanding agentic systems, and explain what Microsoft calls the “frontier firm.” Along the way, they dig into the practical realities that leaders can’t ignore: data sovereignty, the enterprise memory layer, and the line between automating tasks and building truly intelligent workflows. They wrap with a candid look at what’s next for organizations, and for a workforce stepping into a world where AI agents are part of the team. The GuideLine is brought to you by Guidehouse. © 2026 Guidehouse.

13 Apr 2026 - 26 min

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