Heart Failure Beat

HFSA Presidential Voices: Leading the Modern Era of Heart Failure

Priya Umapathi, MD speaks with six HFSA past presidents live from ASM 2025. Nancy M. Albert, PhD, CCNS, CCRN, NE-BC, Biykem Bozkurt, MD, PhD, Jim Fang, MD, FHFSA, Mark H. Drazner, MD MSc, Michael Felker, MD, FHFSA, and Ken Margulies, MD, FHFSA discuss their journeys, achievements, and the future of heart failure — from prevention to precision medicine and AI.

Revisiting the Fundamentals: Hemodynamics at the Heart of Heart Failure Care

Guest editors Drs. Mak, Burkhoff, and Belkin join Heart Failure Beat to unpack the Journal of Cardiac Failure Hemodynamics Focus Issue. They discuss how renewed attention to pressure-volume loops, ECMO, and patient perspectives is reviving interest in hemodynamics as a vital foundation for heart failure care. Discover how simple physiological insights continue to drive complex innovations—and why now is the time to bring hemodynamics back to the center of cardiovascular practice. https://onlinejcf.com/current

Behind the Pages of the New Journal, JCF-Intersections

Meet the editorial team behind JCF-Intersections, HFSA’s and the JCF Family of Journal’s new open-access journal. Drs. Jason Katz and Nosheen Reza share their vision for a journal that sits at the crossroads of heart failure and innovation. From unique article types to early-career mentorship, this is a must-listen for anyone in cardiovascular care. Listen now and read the debut issue of JCF-Intersections, out now at onlinejcfi.org.

Gene Therapy Breakthroughs in Genetic Cardiomyopathies

In this episode of the Heart Failure Beat, Dr. Eric Adler of UC San Diego Health joins the show to discuss his landmark gene therapy trial for Danon disease, recently published in the New England Journal of Medicine. Dr. Adler recounts the powerful bedside-to-bench-to-bedside story that led to the development of a groundbreaking treatment for this severe, genetic cardiomyopathy. He explains the mechanics and evolution of gene therapy, its promise in treating monogenic heart failure syndromes, and the early but encouraging clinical outcomes—like dramatic reductions in troponins and heart mass. The episode also explores regulatory and safety challenges, delivery limitations, and the critical role of patient advocacy. Whether you’re a heart failure specialist or a translational researcher, this conversation offers compelling insights into the future of precision therapies in cardiology.

From Triage to Treatment: A Roadmap for Cardiogenic Shock Response

In this episode of Heart Failure Beat, Dr. Shashank Sinha—Medical Director of the CICU at Inova Fairfax—joins hosts Dr. Priya Umapathi and Dr. Michael Beasley to unpack the 2025 ACC Expert Consensus Statement on Cardiogenic Shock [https://www.jacc.org/doi/10.1016/j.jacc.2025.02.018]. Together, they explore the updated SHARC classification, staging systems, and the S.U.S.P.E.C.T. mnemonic for early recognition. Dr. Sinha shares practical insights on invasive hemodynamics, shock team composition, and new data on mechanical circulatory support. Plus, hear his “Top 10 Takeaways” for managing this complex and dynamic condition. Whether you work in a tertiary center or a community hospital, this episode delivers guidance for real-world care.