Oncology for the Inquisitive Mind

183. ESMO Awards - Episode 3

For our third instalment of ESMO 2025, we explore lung cancer in all its glory, including small cell, mesothelioma and non-small cell lung cancer. Studies: DeLLphi-303 [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=tarlatamab_with_first_line_chemoimmunotherapy_for_] SOHO-01 [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=sevabertinib__bay_2927088__in_advanced_her2_mutant] ALBATROS [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=efficacy_of_lorlatinib_after_failure_of_a_first_li] PAULIEN [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=pembrolizumab_plus_chemotherapy__pem___ct__versus_] DREAM3R [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=primary_results_of_dream3r__durvalumab__medi4736__] OptiTROP-Lung04 [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=sacituzumab_tirumotecan__sac_tmt__vs_platinum_base] For more episodes, resources and blog posts, visit www.inquisitiveonc.com [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com] Please find us on Twitter @InquisitiveOnc! [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!] If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com [inquisitiveonc@gmail.com] Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice. Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. MSD provided virtual participation with ESMO. Our partners have access to the episode at the same time you do and have no editorial control over the content. ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

182. ESMO Awards - Episode 2

ESMO 2025 continues this week with coverage including early breast cancer, metastatic breast cancer and gynaecological malignancies. A mammoth episode covering giants and pioneers of the oncology world. Studies: SOLTI-RIBOLARIS [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=risk_of_recurrence__ror__after_neoadjuvant_ribocic] POSITIVE [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=n5_year_follow_up_results_from_the_positive__pregn] monarchE: [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=monarche__primary_overall_survival__os__results_of] DESTINY-Breast11 [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=destiny_breast11__neoadjuvant_trastuzumab_deruxtec] evERA [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=giredestrant__gire___an_oral_selective_oestrogen_r] ASCENT-03 [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=primary_results_from_ascent_03__a_randomized_phase] TROPION-Breast02 trial [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=first_line__1l__datopotamab_deruxtecan__dato_dxd___757d4a2] ROSELLA [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=rosella__gog3073__engotov72__apgot_ov10___relacori] DICE trial [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=dice_trial__an_international_multi_centre_randomis] ENGOT-ov65/KEYNOTE-B96 study [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=pembrolizumab_vs_placebo_plus_weekly_paclitaxel___] ROSELLA [https://oncologypro.esmo.org/congress-resources/esmo-congress-2025?presentation=rosella__gog3073__engotov72__apgot_ov10___relacori] For more episodes, resources and blog posts, visit www.inquisitiveonc.com [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com] Please find us on Twitter @InquisitiveOnc! [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!] If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com [inquisitiveonc@gmail.com] Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice. Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Virtual participation with ESMO was provided by MSD. Our partners have access to the episode at the same time you do and have no editorial control over the content. ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

182. ESMO Awards - Episode 1

After a short break for some pretty major life changes (more details in the episode), Josh and Michael return to tackle the best and brightest of ESMO 2025. With support from MSD, our dynamic duo play host to the inaugural Oncology for the Inquisitive Mind Awards. Today, they look at studies in pre-clinical science, supportive care and rare cancers to find their favourite studies amidst the goldmine that was this year's European Oncology Extravaganza. For more episodes, resources and blog posts, visit www.inquisitiveonc.com [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com] Please find us on Twitter @InquisitiveOnc! [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!] If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com [inquisitiveonc@gmail.com] Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice. Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Virtual participation with ESMO was provided by MSD. Our partners have access to the episode at the same time you do and have no editorial control over the content. ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

181. Back to Basics - Limited Stage Small Cell Lung Cancer

In this episode, the focus shifts away from the more "garden-variety" non-small cell lung cancer and to its less common, frequently more aggressive sibling, small cell lung cancer. Here, Josh and Michael examine the management of limited-stage small cell lung cancer, which while accounting for a minority of cases, is no less interesting and potentially confusing. Studies discussed in this episode: PCI Meta Analysis ADRIATIC For more episodes, resources and blog posts, visit www.inquisitiveonc.com [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com] Please find us on Twitter @InquisitiveOnc! [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!] If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com [inquisitiveonc@gmail.com] Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice. Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content. ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.

180. Back to Basics - Metastatic NSCLC feat. KRAS and MET mutations

On this week's episode, Josh and Michael exchange the established treatment landscape of EGFR and ALK mutant NSCLC for the developing management of disease harbouring KRAS and MET mutations. The most common mutation meets one of the least common in this battle of therapeutic tenacity. Studies discussed in this episode: INSIGHT-2 KRYSTAL-12 For more episodes, resources and blog posts, visit www.inquisitiveonc.com [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com] Please find us on Twitter @InquisitiveOnc! [https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!] If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com [inquisitiveonc@gmail.com] Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice. Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content. ---------------------------------------- Hosted on Acast. See acast.com/privacy [https://acast.com/privacy] for more information.